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The map label for this gene is xseA [H]

Identifier: 58616751

GI number: 58616751

Start: 28450

End: 29616

Strand: Reverse

Name: xseA [H]

Synonym: ERGA_CDS_00240

Alternate gene names: 58616751

Gene position: 29616-28450 (Counterclockwise)

Preceding gene: 58616752

Following gene: 58616749

Centisome position: 1.97

GC content: 29.22

Gene sequence:

>1167_bases
ATGATATTAGAATTTACCGTTAGTGAAATCACAAAAATTTTTCAAAATTTAGTACATGAAACATTTAATCATATAAAAGT
TAGAGGAGAAATCAGTAACCTATCACAACCAAAATCTGGACATACGTATTTCACATTAAAAGATCATCAAGCAGTACTTA
ATGCAGTATGTTGGAATAATACCAAAATTGAGATAGACCTTAAAAATGGACTAGAGGTGATATGTATTGGTTTTCTCACA
ACTTACCAGTCAAAATATCAAATAATAATAGAAAGTATGTTATTATCTGGTATAGGAAACTTAGAAATTATGCTTCAGCA
AAGAAAAGCAAAACTAGAAAAGGAAGGTCTGTTTGATCAGTCTCGAAAAAAAACATTACCTTTATTACCAAAAACTATAG
GTGTGATTACATCTACCACTGGTGCTGCTATCAACGACATATTAAACAGAGTAAAAAGTCGTTTTCCAAGTCATATAGTC
ATATTCCCAGTACTTGTGCAAGGTAATGATGCAGTAACACAAATTGTAAATGCAATACATAAATCAAATAACACAGAAAC
TGACTGTCCTGATGTTCTCATTATTGCCAGAGGAGGAGGCAGTGTAGAAGATTTATGGATTTTTAATGATGAACTGATAG
TAAGAGCAATAGCTAAATCTAGAATTCCCATAGTCTCTGCAATTGGGCATGAAACTGATTTTACACTAGTCGATTATGCA
GCAGATGTAAGAGCTCCTACTCCTACAGCTGCAGTAGAGATTATTTTACCAACAAAAATCCAAGTAACAGAATATATAAA
CAGCAAGTTCAATAAAATAAAAGCAGCATTGCACTATACTGTGAACACAAAAAGAAATAAGTTATTATATTTTCATAATC
AATTAGAAATAACCAGACATAAAATAAAAGTACTGAAATTACAGCTGTTCAAACACAAAAATAAAGTAGAAATTTTATTA
AAGGTAATATTATTAAACAAAAGACAATACTTAAATGATTTATATTATAAAATAAGTAAATATAATAAAGAAAAGAATTT
AGAATTAGGCTATGCTGTGATATATGATAAAAATCATCAACATATCAGTAGTGTCAAAAAGCTACAAAAAAATGACATAA
TATCAATTGAATTACAAGATGGCTTTATAAAGGCAATAGTACAGTAG

Upstream 100 bases:

>100_bases
CACAACCAAAATCTGGACATACATATTTTACATTAAAAGATCATCAAGCAGTACTTAATGCAGTATGCTGGAATAATATA
AAATTTGAAGTCGTTGTTTT

Downstream 100 bases:

>100_bases
AATAAATGCTATTATACTTAATTAATAGTCAAATAAAACAAATTACCGAATATTAATTGATTTGATACATATAGAATACT
AAAAGAAAATTCCTATATTT

Product: putative exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MILEFTVSEITKIFQNLVHETFNHIKVRGEISNLSQPKSGHTYFTLKDHQAVLNAVCWNNTKIEIDLKNGLEVICIGFLT
TYQSKYQIIIESMLLSGIGNLEIMLQQRKAKLEKEGLFDQSRKKTLPLLPKTIGVITSTTGAAINDILNRVKSRFPSHIV
IFPVLVQGNDAVTQIVNAIHKSNNTETDCPDVLIIARGGGSVEDLWIFNDELIVRAIAKSRIPIVSAIGHETDFTLVDYA
ADVRAPTPTAAVEIILPTKIQVTEYINSKFNKIKAALHYTVNTKRNKLLYFHNQLEITRHKIKVLKLQLFKHKNKVEILL
KVILLNKRQYLNDLYYKISKYNKEKNLELGYAVIYDKNHQHISSVKKLQKNDIISIELQDGFIKAIVQ

Sequences:

>Translated_388_residues
MILEFTVSEITKIFQNLVHETFNHIKVRGEISNLSQPKSGHTYFTLKDHQAVLNAVCWNNTKIEIDLKNGLEVICIGFLT
TYQSKYQIIIESMLLSGIGNLEIMLQQRKAKLEKEGLFDQSRKKTLPLLPKTIGVITSTTGAAINDILNRVKSRFPSHIV
IFPVLVQGNDAVTQIVNAIHKSNNTETDCPDVLIIARGGGSVEDLWIFNDELIVRAIAKSRIPIVSAIGHETDFTLVDYA
ADVRAPTPTAAVEIILPTKIQVTEYINSKFNKIKAALHYTVNTKRNKLLYFHNQLEITRHKIKVLKLQLFKHKNKVEILL
KVILLNKRQYLNDLYYKISKYNKEKNLELGYAVIYDKNHQHISSVKKLQKNDIISIELQDGFIKAIVQ
>Mature_388_residues
MILEFTVSEITKIFQNLVHETFNHIKVRGEISNLSQPKSGHTYFTLKDHQAVLNAVCWNNTKIEIDLKNGLEVICIGFLT
TYQSKYQIIIESMLLSGIGNLEIMLQQRKAKLEKEGLFDQSRKKTLPLLPKTIGVITSTTGAAINDILNRVKSRFPSHIV
IFPVLVQGNDAVTQIVNAIHKSNNTETDCPDVLIIARGGGSVEDLWIFNDELIVRAIAKSRIPIVSAIGHETDFTLVDYA
ADVRAPTPTAAVEIILPTKIQVTEYINSKFNKIKAALHYTVNTKRNKLLYFHNQLEITRHKIKVLKLQLFKHKNKVEILL
KVILLNKRQYLNDLYYKISKYNKEKNLELGYAVIYDKNHQHISSVKKLQKNDIISIELQDGFIKAIVQ

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=436, Percent_Identity=35.0917431192661, Blast_Score=260, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 44180; Mature: 44180

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILEFTVSEITKIFQNLVHETFNHIKVRGEISNLSQPKSGHTYFTLKDHQAVLNAVCWNN
CEEEEEHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEECHHHHHHHHHCCC
TKIEIDLKNGLEVICIGFLTTYQSKYQIIIESMLLSGIGNLEIMLQQRKAKLEKEGLFDQ
CEEEEEECCCCEEEEEEHHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCC
SRKKTLPLLPKTIGVITSTTGAAINDILNRVKSRFPSHIVIFPVLVQGNDAVTQIVNAIH
CCCCCCCCCCHHHHHEECCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHHHHHHH
KSNNTETDCPDVLIIARGGGSVEDLWIFNDELIVRAIAKSRIPIVSAIGHETDFTLVDYA
HCCCCCCCCCCEEEEECCCCCEEEEEEECHHHHHHHHHHCCCCEEEECCCCCCCEEEEEH
ADVRAPTPTAAVEIILPTKIQVTEYINSKFNKIKAALHYTVNTKRNKLLYFHNQLEITRH
HHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEEEEEEEECCCCEEEEEECCHHHHHH
KIKVLKLQLFKHKNKVEILLKVILLNKRQYLNDLYYKISKYNKEKNLELGYAVIYDKNHQ
HHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCH
HISSVKKLQKNDIISIELQDGFIKAIVQ
HHHHHHHHHCCCEEEEEECCCHHHHHCC
>Mature Secondary Structure
MILEFTVSEITKIFQNLVHETFNHIKVRGEISNLSQPKSGHTYFTLKDHQAVLNAVCWNN
CEEEEEHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEECHHHHHHHHHCCC
TKIEIDLKNGLEVICIGFLTTYQSKYQIIIESMLLSGIGNLEIMLQQRKAKLEKEGLFDQ
CEEEEEECCCCEEEEEEHHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCC
SRKKTLPLLPKTIGVITSTTGAAINDILNRVKSRFPSHIVIFPVLVQGNDAVTQIVNAIH
CCCCCCCCCCHHHHHEECCCCHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHHHHHHH
KSNNTETDCPDVLIIARGGGSVEDLWIFNDELIVRAIAKSRIPIVSAIGHETDFTLVDYA
HCCCCCCCCCCEEEEECCCCCEEEEEEECHHHHHHHHHHCCCCEEEECCCCCCCEEEEEH
ADVRAPTPTAAVEIILPTKIQVTEYINSKFNKIKAALHYTVNTKRNKLLYFHNQLEITRH
HHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEEEEEEEECCCCEEEEEECCHHHHHH
KIKVLKLQLFKHKNKVEILLKVILLNKRQYLNDLYYKISKYNKEKNLELGYAVIYDKNHQ
HHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCH
HISSVKKLQKNDIISIELQDGFIKAIVQ
HHHHHHHHHCCCEEEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA