Click here to switch to the map view.

The map label for this gene is glmS [H]

Identifier: 56965832

GI number: 56965832

Start: 4250129

End: 4251223

Strand: Direct

Name: glmS [H]

Synonym: ABC4074

Alternate gene names: 56965832

Gene position: 4250129-4251223 (Clockwise)

Preceding gene: 56965831

Following gene: 56965833

Centisome position: 98.75

GC content: 42.19

Gene sequence:

>1095_bases
GTGAAAACACAAGTTGATAATAAAGTAAGAGCGTATATTGGTGAGACACCTGTTGTATTATCAAGGATTTTAGAAGAAAG
ACAGTCTATTCTTTCTGAACTTGTCGATCTCGTTACAGGTCAAGACGTCTCAAACATATTGATTGTTGGATCTGGTTCTT
CTTATCACTCGGCCGTAGCTGTCCAAGCTTTCGTAGAAAAAAGCTTACAAATGGCAGTGAAGGTTCAGTATCCAACACGT
TTCACAAATGAAGTGATTGCGCCTGAAAAAGGGACGCTAGTCATTGGCATTTCGCAGGGAGGAAAGAGTTTATCGACATT
AAGAGCGATTTCTAAAGCACAGGAAGGTGGGCTGAAAACCGTCGGCATCACGGCTACAAAGGATAGTGAACTTGCTAAGA
GACCTGACCTTTTTGTACCAATTGCATGCGGAGAAGAACAAGCAGGTGCAAAAACAAAAGGTGTGGCAGCAACGATGCTG
ACTTTATTGTTATTAGGGCTAGAAGTCGGGAAAAAGCAAGGGTATTATGAGGAACAGGCCTATCAAGAATGGATTCGTAA
GATAGAAGCGACAATTGAAAATTTGCCTGTTGTAATAGCATCTGCAGAAAGTTGGGTCAACCAATACATGAATGAATTTT
CCGTTGCCCCACAATTGATGGTCATTGGCTACGGCCCCCATTATGCAATAGCTCTAGAAGGCGGGCTAAAGATTTTAGAA
ACTGTTCGTATTCCAGCTCTAGGCTACGAGATGGAAGAGTACATGCACGGAATTTATAATTGTATCAATGAAGACAATCA
CCTGATCTTCTTGGCAAGTGAAGGAGCAGCAGAAGAACAGAGGCGTTTGCTTAAGATGAGAAAGTTCTTAGGCGAACATA
CGTTAAAGACTTATGTTATCGGCGGAAAAGACATTCAAAGGGAGAGTGGCAGGGACTTGCTAATGCCACTGGTAAATGAC
CCTATACTATCCATATTCGAGTATCTTATACCACTTCAGCTCATAGCGGCTCTGGTGCCTTTAAAGAAAGGAATTAACCC
TGCCATTCCTAAGTTTACATCGTTCCATCAACAGATGGGCAGCAAGCTCCAATAA

Upstream 100 bases:

>100_bases
AAGAACGTGAAAGTCAATTACATTATGTTAGGCATAATTGCCCTTGGCATTCTCGGAACGTGGGTTGGAATTTTATAATA
TGAAAATGGAGGAATGTAAA

Downstream 100 bases:

>100_bases
AAAGTTGGGGGTGGGTAGCCAGTTTATTGCTCACCCCCTAAATATATCAATCGAGTAAGGATAGATAAGGTTGGTGACTC
ATGAAAACTCAGATCCTACA

Product: hypothetical protein

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKTQVDNKVRAYIGETPVVLSRILEERQSILSELVDLVTGQDVSNILIVGSGSSYHSAVAVQAFVEKSLQMAVKVQYPTR
FTNEVIAPEKGTLVIGISQGGKSLSTLRAISKAQEGGLKTVGITATKDSELAKRPDLFVPIACGEEQAGAKTKGVAATML
TLLLLGLEVGKKQGYYEEQAYQEWIRKIEATIENLPVVIASAESWVNQYMNEFSVAPQLMVIGYGPHYAIALEGGLKILE
TVRIPALGYEMEEYMHGIYNCINEDNHLIFLASEGAAEEQRRLLKMRKFLGEHTLKTYVIGGKDIQRESGRDLLMPLVND
PILSIFEYLIPLQLIAALVPLKKGINPAIPKFTSFHQQMGSKLQ

Sequences:

>Translated_364_residues
MKTQVDNKVRAYIGETPVVLSRILEERQSILSELVDLVTGQDVSNILIVGSGSSYHSAVAVQAFVEKSLQMAVKVQYPTR
FTNEVIAPEKGTLVIGISQGGKSLSTLRAISKAQEGGLKTVGITATKDSELAKRPDLFVPIACGEEQAGAKTKGVAATML
TLLLLGLEVGKKQGYYEEQAYQEWIRKIEATIENLPVVIASAESWVNQYMNEFSVAPQLMVIGYGPHYAIALEGGLKILE
TVRIPALGYEMEEYMHGIYNCINEDNHLIFLASEGAAEEQRRLLKMRKFLGEHTLKTYVIGGKDIQRESGRDLLMPLVND
PILSIFEYLIPLQLIAALVPLKKGINPAIPKFTSFHQQMGSKLQ
>Mature_364_residues
MKTQVDNKVRAYIGETPVVLSRILEERQSILSELVDLVTGQDVSNILIVGSGSSYHSAVAVQAFVEKSLQMAVKVQYPTR
FTNEVIAPEKGTLVIGISQGGKSLSTLRAISKAQEGGLKTVGITATKDSELAKRPDLFVPIACGEEQAGAKTKGVAATML
TLLLLGLEVGKKQGYYEEQAYQEWIRKIEATIENLPVVIASAESWVNQYMNEFSVAPQLMVIGYGPHYAIALEGGLKILE
TVRIPALGYEMEEYMHGIYNCINEDNHLIFLASEGAAEEQRRLLKMRKFLGEHTLKTYVIGGKDIQRESGRDLLMPLVND
PILSIFEYLIPLQLIAALVPLKKGINPAIPKFTSFHQQMGSKLQ

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=311, Percent_Identity=26.3665594855305, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI205277386, Length=318, Percent_Identity=23.8993710691824, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1790167, Length=317, Percent_Identity=26.813880126183, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17539970, Length=252, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17532899, Length=222, Percent_Identity=25.2252252252252, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17532897, Length=222, Percent_Identity=25.2252252252252, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322745, Length=326, Percent_Identity=22.3926380368098, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357745, Length=308, Percent_Identity=24.6753246753247, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 40079; Mature: 40079

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQVDNKVRAYIGETPVVLSRILEERQSILSELVDLVTGQDVSNILIVGSGSSYHSAVA
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHH
VQAFVEKSLQMAVKVQYPTRFTNEVIAPEKGTLVIGISQGGKSLSTLRAISKAQEGGLKT
HHHHHHHHHHEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEE
VGITATKDSELAKRPDLFVPIACGEEQAGAKTKGVAATMLTLLLLGLEVGKKQGYYEEQA
EEEEECCCCHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
YQEWIRKIEATIENLPVVIASAESWVNQYMNEFSVAPQLMVIGYGPHYAIALEGGLKILE
HHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHH
TVRIPALGYEMEEYMHGIYNCINEDNHLIFLASEGAAEEQRRLLKMRKFLGEHTLKTYVI
HHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHEEEEE
GGKDIQRESGRDLLMPLVNDPILSIFEYLIPLQLIAALVPLKKGINPAIPKFTSFHQQMG
CCCHHHHCCCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
SKLQ
CCCC
>Mature Secondary Structure
MKTQVDNKVRAYIGETPVVLSRILEERQSILSELVDLVTGQDVSNILIVGSGSSYHSAVA
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHH
VQAFVEKSLQMAVKVQYPTRFTNEVIAPEKGTLVIGISQGGKSLSTLRAISKAQEGGLKT
HHHHHHHHHHEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEE
VGITATKDSELAKRPDLFVPIACGEEQAGAKTKGVAATMLTLLLLGLEVGKKQGYYEEQA
EEEEECCCCHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
YQEWIRKIEATIENLPVVIASAESWVNQYMNEFSVAPQLMVIGYGPHYAIALEGGLKILE
HHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHH
TVRIPALGYEMEEYMHGIYNCINEDNHLIFLASEGAAEEQRRLLKMRKFLGEHTLKTYVI
HHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHEEEEE
GGKDIQRESGRDLLMPLVNDPILSIFEYLIPLQLIAALVPLKKGINPAIPKFTSFHQQMG
CCCHHHHCCCCCEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
SKLQ
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA