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The map label for this gene is bmrU [H]

Identifier: 56965732

GI number: 56965732

Start: 4135953

End: 4136864

Strand: Direct

Name: bmrU [H]

Synonym: ABC3974

Alternate gene names: 56965732

Gene position: 4135953-4136864 (Clockwise)

Preceding gene: 56965731

Following gene: 56965735

Centisome position: 96.1

GC content: 46.6

Gene sequence:

>912_bases
ATGCCCCGTTACGAAAAAGCCATTCTGCTCTACAATAGGAACGCAGGGCAAGGAGACGTCAACGAACTGCTGCAACAAAC
ATTGGCAACACTTGCCCCTGAAGTAATAGAGCTGACATTGATCCAGACGCAAGCGCCAGGCGAAGCAAAACAACGATGCA
AACAGTTGCCTGAGGACATCGAACTATTGATCATCGTGGGCGGCGACGGCACCGTCCATGAATGCGTCAACGGGTTGATG
GCAGGAAACAACCAACCAACTGTGGCAATTGTGCCAGCTGGCACGTGCAATGACTTGGCTCGAAGCTTGCAAATTCCTAC
AGTAGACGACGCCCTCACAGCAATTGTAAACGGCACAACTGTTGCGATTGACATCGGCCAACAAAACGACAGCTACTTTG
CCAACTTTTCTGGAGTAGGCATGATTGTCGAGGCTTCAAAAGAAATAGAAGCAGAAACAAAAGCACGTTTTGGAAAACTT
GGGTATATCATTAGCGCAATTCGATCGATCAAAGAACCAAAACCATTTTCGTACACGATCACAACAGCAAAAGGAGAAAC
ATCTAGCGGCGATGCCGTTATGATCTTAGCGATGAACGGCCAATACATTGGCACAATCGGCCTATTCTTAAAAGACATCT
CCCTTTCAGACGGCAAACTTCATCTGTTTATTGTCAAGGAGGCAGGCTTCACGCTCTTAAAAAATATGTACAGCCACGCT
TTCACCGATGAAAATTGGCTTAACGACGCAGAAGGGATCGAAGCACTCGAACTCGATCAATTTACACTCACATGCCGCCA
AACGCTCGATGTCGACAGCGATGGCGAAATCAATGAACAGACACCCGTCTCCTATACACTTCATCAACAGGCCCTTACTT
TTATTACTACAGAACAACAAGAAAAAGACTGA

Upstream 100 bases:

>100_bases
CTAAAATGCTTAAAAACGGGTACATGTATGACAAAGCATGGAAAACGATTCCTTCGTTTTCCAATTGGAAAGTGATCTTA
AGCTGAAAGGTGGACATGGC

Downstream 100 bases:

>100_bases
GGATGCGATGAGGATAGGGAAACCGGTTTGTTTGATCGTTGGCGTTAAAAAGAAGACATTGGGAGCGAAATGGGCTAGGC
CGCAAACGTGTTTGCGGCCT

Product: multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPRYEKAILLYNRNAGQGDVNELLQQTLATLAPEVIELTLIQTQAPGEAKQRCKQLPEDIELLIIVGGDGTVHECVNGLM
AGNNQPTVAIVPAGTCNDLARSLQIPTVDDALTAIVNGTTVAIDIGQQNDSYFANFSGVGMIVEASKEIEAETKARFGKL
GYIISAIRSIKEPKPFSYTITTAKGETSSGDAVMILAMNGQYIGTIGLFLKDISLSDGKLHLFIVKEAGFTLLKNMYSHA
FTDENWLNDAEGIEALELDQFTLTCRQTLDVDSDGEINEQTPVSYTLHQQALTFITTEQQEKD

Sequences:

>Translated_303_residues
MPRYEKAILLYNRNAGQGDVNELLQQTLATLAPEVIELTLIQTQAPGEAKQRCKQLPEDIELLIIVGGDGTVHECVNGLM
AGNNQPTVAIVPAGTCNDLARSLQIPTVDDALTAIVNGTTVAIDIGQQNDSYFANFSGVGMIVEASKEIEAETKARFGKL
GYIISAIRSIKEPKPFSYTITTAKGETSSGDAVMILAMNGQYIGTIGLFLKDISLSDGKLHLFIVKEAGFTLLKNMYSHA
FTDENWLNDAEGIEALELDQFTLTCRQTLDVDSDGEINEQTPVSYTLHQQALTFITTEQQEKD
>Mature_302_residues
PRYEKAILLYNRNAGQGDVNELLQQTLATLAPEVIELTLIQTQAPGEAKQRCKQLPEDIELLIIVGGDGTVHECVNGLMA
GNNQPTVAIVPAGTCNDLARSLQIPTVDDALTAIVNGTTVAIDIGQQNDSYFANFSGVGMIVEASKEIEAETKARFGKLG
YIISAIRSIKEPKPFSYTITTAKGETSSGDAVMILAMNGQYIGTIGLFLKDISLSDGKLHLFIVKEAGFTLLKNMYSHAF
TDENWLNDAEGIEALELDQFTLTCRQTLDVDSDGEINEQTPVSYTLHQQALTFITTEQQEKD

Specific function: May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro [H]

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

Organism=Escherichia coli, GI1788402, Length=283, Percent_Identity=27.5618374558304, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: NA

Molecular weight: Translated: 32979; Mature: 32848

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRYEKAILLYNRNAGQGDVNELLQQTLATLAPEVIELTLIQTQAPGEAKQRCKQLPEDI
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCHHHEEEEEEEECCCCHHHHHHHHCCCCE
ELLIIVGGDGTVHECVNGLMAGNNQPTVAIVPAGTCNDLARSLQIPTVDDALTAIVNGTT
EEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHCCCEE
VAIDIGQQNDSYFANFSGVGMIVEASKEIEAETKARFGKLGYIISAIRSIKEPKPFSYTI
EEEEECCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TTAKGETSSGDAVMILAMNGQYIGTIGLFLKDISLSDGKLHLFIVKEAGFTLLKNMYSHA
EECCCCCCCCCEEEEEEECCCEEEEHHHHHEECCCCCCEEEEEEEECCCHHHHHHHHHHH
FTDENWLNDAEGIEALELDQFTLTCRQTLDVDSDGEINEQTPVSYTLHQQALTFITTEQQ
CCCCCCCCCCCCCCEEEECCEEEEEHHHCCCCCCCCCCCCCCCEEEEHHHHEEEEECCCC
EKD
CCC
>Mature Secondary Structure 
PRYEKAILLYNRNAGQGDVNELLQQTLATLAPEVIELTLIQTQAPGEAKQRCKQLPEDI
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHCHHHEEEEEEEECCCCHHHHHHHHCCCCE
ELLIIVGGDGTVHECVNGLMAGNNQPTVAIVPAGTCNDLARSLQIPTVDDALTAIVNGTT
EEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHCCCEE
VAIDIGQQNDSYFANFSGVGMIVEASKEIEAETKARFGKLGYIISAIRSIKEPKPFSYTI
EEEEECCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TTAKGETSSGDAVMILAMNGQYIGTIGLFLKDISLSDGKLHLFIVKEAGFTLLKNMYSHA
EECCCCCCCCCEEEEEEECCCEEEEHHHHHEECCCCCCEEEEEEEECCCHHHHHHHHHHH
FTDENWLNDAEGIEALELDQFTLTCRQTLDVDSDGEINEQTPVSYTLHQQALTFITTEQQ
CCCCCCCCCCCCCCEEEECCEEEEEHHHCCCCCCCCCCCCCCCEEEEHHHHEEEEECCCC
EKD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7961792; 8969508; 9384377 [H]