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The map label for this gene is yisV [H]

Identifier: 56965694

GI number: 56965694

Start: 4092677

End: 4094152

Strand: Direct

Name: yisV [H]

Synonym: ABC3936

Alternate gene names: 56965694

Gene position: 4092677-4094152 (Clockwise)

Preceding gene: 56965690

Following gene: 56965695

Centisome position: 95.09

GC content: 40.38

Gene sequence:

>1476_bases
TTGAAAATAGAAATAAATCGGCATTCTGACATACCGATTGCCCAACAAATTCAAGAGAACATCGCTGACCGGATTCGCTC
CAACTTGCTCGAAGAAGGAAGCAAGTTACCATCTGTCCGTAAACTAGCAGAACAAACTGGAGTAAGTCTTATGACTGCAA
ACAAAGCTTATAACCATTTAGAGAAACAAGGGTTGATCGAAAAAGTCCAAGGAAAAGGGACTTTTGTCCGAAAAAGTAGC
GGGGCAAGCAAAACGGAAAACGAAAAAAAGCTGCTATCTTATGATTGGCAATTAACCGTTACTGATTACTTGCCACGTGC
TCAGTACATGCAATTTAATACAGGGAAAGAAAAAATCCAGTTTTCCTCCTCTAAGATATGGCCCAACTTACTTCCGAACC
GTTACCTCATAAAAGAAACAATACAGATCCTTTCGGAGGAACCATATATACTTTCTACTTATGGAGAAGGACGAGGAGAC
ATTACGCTAAGAAAAGAAATGTCCGCTTATTTAAAACATTTAAAGATAGCAATTGAACCAGACGATATCGTCATTACAAA
TGGGGTGCAACAAGGCATTGATATTGTTGCCCGTAGTTTTGTTGGCCCAGGAGACGTTGTGGTTACCGAGACTCCTACTT
ACTCGGCGGCAATTGACGTATTCAGAGGGAGAGGAGCATCGATTGTATCGATTCCAGTTGACGAGAACGGAATGAGAGTG
GATTTACTACCATCATTGAAAAATAAACCAAAGGTGATTTATACAATCCCCTCTTTTCAAAATCCAACTGGAACATTGCT
CAGTAAAAAGCGACGGCAACTACTGCTTGATTTTGCGCAATCGAACGAGATTATTATAATTGAAGACGATTCTTGGAGTG
AAATTTATTTTGACAGTAAACCCCCGCTGCCAATAAAAAGCTTAGATGAGTATGGTCATGTGATTTATTTGAAAGGATTA
AGCAAAACGCTGTCTCCAGGGTGTCGAATTGGGGTGATGGCTACTTCTGGTACGAATTTGAACAGAATCATAGCCGCCAA
AACTATTACCGATTTAGGCACTCCTCTATTAAACCAAAAGGCGGTGCTGTCTTTTTTACGTTCGAATCGAATGAAAGAGC
ATATAAAAAAGCTGCGGATCGCTTTAAAATTAAGAAGGGATCGCGTTATCGATCTTCTTACTGTATATGCCCCGAAGGAA
GTAACGTGGATTGTCCCAAAAGGAGGAGTCAATATTTGGATATCGCTGCCCCCTTGGGTCGATACCAATGAAATGCTGTT
TGAAGCAAAGAAATTTGGTATCTCCTTTCTCCCTGGATCTGCTTGCTATCCTAAAGAACCTGCCATGAATCACCTGCGGC
TGTGTTTTGCTGCTGTAGATGATCAATTATTAGAAACGGGCATCAAGACACTTTGTAAAATTTTTACGACCTTTATTGAA
GAACGCAATGAAGAATCAAACATGCCTCTTGTTTAA

Upstream 100 bases:

>100_bases
TCCACCTGTCAATTGTTATATGTTACAATTCATTTAAACTAATTTTAGAATAAGACTGTATAACAGTAAATAAACACACA
TAACAGATGGAGGTGTTTTT

Downstream 100 bases:

>100_bases
CCAAGTCATTCTGTAGACTTTCAGTCACTGAATGGCTATTTTTGCTGGGTATCCAGTAGCAAACATGCCAAAAAAGGAAC
GTTTAACTGTTATACATCAA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MKIEINRHSDIPIAQQIQENIADRIRSNLLEEGSKLPSVRKLAEQTGVSLMTANKAYNHLEKQGLIEKVQGKGTFVRKSS
GASKTENEKKLLSYDWQLTVTDYLPRAQYMQFNTGKEKIQFSSSKIWPNLLPNRYLIKETIQILSEEPYILSTYGEGRGD
ITLRKEMSAYLKHLKIAIEPDDIVITNGVQQGIDIVARSFVGPGDVVVTETPTYSAAIDVFRGRGASIVSIPVDENGMRV
DLLPSLKNKPKVIYTIPSFQNPTGTLLSKKRRQLLLDFAQSNEIIIIEDDSWSEIYFDSKPPLPIKSLDEYGHVIYLKGL
SKTLSPGCRIGVMATSGTNLNRIIAAKTITDLGTPLLNQKAVLSFLRSNRMKEHIKKLRIALKLRRDRVIDLLTVYAPKE
VTWIVPKGGVNIWISLPPWVDTNEMLFEAKKFGISFLPGSACYPKEPAMNHLRLCFAAVDDQLLETGIKTLCKIFTTFIE
ERNEESNMPLV

Sequences:

>Translated_491_residues
MKIEINRHSDIPIAQQIQENIADRIRSNLLEEGSKLPSVRKLAEQTGVSLMTANKAYNHLEKQGLIEKVQGKGTFVRKSS
GASKTENEKKLLSYDWQLTVTDYLPRAQYMQFNTGKEKIQFSSSKIWPNLLPNRYLIKETIQILSEEPYILSTYGEGRGD
ITLRKEMSAYLKHLKIAIEPDDIVITNGVQQGIDIVARSFVGPGDVVVTETPTYSAAIDVFRGRGASIVSIPVDENGMRV
DLLPSLKNKPKVIYTIPSFQNPTGTLLSKKRRQLLLDFAQSNEIIIIEDDSWSEIYFDSKPPLPIKSLDEYGHVIYLKGL
SKTLSPGCRIGVMATSGTNLNRIIAAKTITDLGTPLLNQKAVLSFLRSNRMKEHIKKLRIALKLRRDRVIDLLTVYAPKE
VTWIVPKGGVNIWISLPPWVDTNEMLFEAKKFGISFLPGSACYPKEPAMNHLRLCFAAVDDQLLETGIKTLCKIFTTFIE
ERNEESNMPLV
>Mature_491_residues
MKIEINRHSDIPIAQQIQENIADRIRSNLLEEGSKLPSVRKLAEQTGVSLMTANKAYNHLEKQGLIEKVQGKGTFVRKSS
GASKTENEKKLLSYDWQLTVTDYLPRAQYMQFNTGKEKIQFSSSKIWPNLLPNRYLIKETIQILSEEPYILSTYGEGRGD
ITLRKEMSAYLKHLKIAIEPDDIVITNGVQQGIDIVARSFVGPGDVVVTETPTYSAAIDVFRGRGASIVSIPVDENGMRV
DLLPSLKNKPKVIYTIPSFQNPTGTLLSKKRRQLLLDFAQSNEIIIIEDDSWSEIYFDSKPPLPIKSLDEYGHVIYLKGL
SKTLSPGCRIGVMATSGTNLNRIIAAKTITDLGTPLLNQKAVLSFLRSNRMKEHIKKLRIALKLRRDRVIDLLTVYAPKE
VTWIVPKGGVNIWISLPPWVDTNEMLFEAKKFGISFLPGSACYPKEPAMNHLRLCFAAVDDQLLETGIKTLCKIFTTFIE
ERNEESNMPLV

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=339, Percent_Identity=26.2536873156342, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI33469970, Length=339, Percent_Identity=26.2536873156342, Blast_Score=126, Evalue=5e-29,
Organism=Escherichia coli, GI1787710, Length=473, Percent_Identity=28.5412262156448, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1790797, Length=433, Percent_Identity=27.4826789838337, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1788722, Length=292, Percent_Identity=24.6575342465753, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321236, Length=358, Percent_Identity=25.1396648044693, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6321000, Length=390, Percent_Identity=25.1282051282051, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6321929, Length=228, Percent_Identity=24.1228070175439, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21356535, Length=361, Percent_Identity=24.3767313019391, Blast_Score=93, Evalue=5e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55280; Mature: 55280

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEINRHSDIPIAQQIQENIADRIRSNLLEEGSKLPSVRKLAEQTGVSLMTANKAYNHL
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEECHHHHHHH
EKQGLIEKVQGKGTFVRKSSGASKTENEKKLLSYDWQLTVTDYLPRAQYMQFNTGKEKIQ
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEECEEEEEHHHCCCCCEEEECCCCHHEE
FSSSKIWPNLLPNRYLIKETIQILSEEPYILSTYGEGRGDITLRKEMSAYLKHLKIAIEP
ECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHCEEEECC
DDIVITNGVQQGIDIVARSFVGPGDVVVTETPTYSAAIDVFRGRGASIVSIPVDENGMRV
CCEEEECCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCEE
DLLPSLKNKPKVIYTIPSFQNPTGTLLSKKRRQLLLDFAQSNEIIIIEDDSWSEIYFDSK
EECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCC
PPLPIKSLDEYGHVIYLKGLSKTLSPGCRIGVMATSGTNLNRIIAAKTITDLGTPLLNQK
CCCCCHHHHCCCCEEEEECCCHHCCCCCEEEEEEECCCCCCEEEEHHHHHHCCCCCCCHH
AVLSFLRSNRMKEHIKKLRIALKLRRDRVIDLLTVYAPKEVTWIVPKGGVNIWISLPPWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHEEECCCCEEEEEECCCCEEEEECCCCC
DTNEMLFEAKKFGISFLPGSACYPKEPAMNHLRLCFAAVDDQLLETGIKTLCKIFTTFIE
CCHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERNEESNMPLV
HCCCCCCCCCC
>Mature Secondary Structure
MKIEINRHSDIPIAQQIQENIADRIRSNLLEEGSKLPSVRKLAEQTGVSLMTANKAYNHL
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEECHHHHHHH
EKQGLIEKVQGKGTFVRKSSGASKTENEKKLLSYDWQLTVTDYLPRAQYMQFNTGKEKIQ
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEECEEEEEHHHCCCCCEEEECCCCHHEE
FSSSKIWPNLLPNRYLIKETIQILSEEPYILSTYGEGRGDITLRKEMSAYLKHLKIAIEP
ECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHCEEEECC
DDIVITNGVQQGIDIVARSFVGPGDVVVTETPTYSAAIDVFRGRGASIVSIPVDENGMRV
CCEEEECCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHCCCCCEEEEEEECCCCCEE
DLLPSLKNKPKVIYTIPSFQNPTGTLLSKKRRQLLLDFAQSNEIIIIEDDSWSEIYFDSK
EECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCC
PPLPIKSLDEYGHVIYLKGLSKTLSPGCRIGVMATSGTNLNRIIAAKTITDLGTPLLNQK
CCCCCHHHHCCCCEEEEECCCHHCCCCCEEEEEEECCCCCCEEEEHHHHHHCCCCCCCHH
AVLSFLRSNRMKEHIKKLRIALKLRRDRVIDLLTVYAPKEVTWIVPKGGVNIWISLPPWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHEEECCCCEEEEEECCCCEEEEECCCCC
DTNEMLFEAKKFGISFLPGSACYPKEPAMNHLRLCFAAVDDQLLETGIKTLCKIFTTFIE
CCHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERNEESNMPLV
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]