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The map label for this gene is galE [H]

Identifier: 56965580

GI number: 56965580

Start: 3982582

End: 3983598

Strand: Direct

Name: galE [H]

Synonym: ABC3822

Alternate gene names: 56965580

Gene position: 3982582-3983598 (Clockwise)

Preceding gene: 56965576

Following gene: 56965581

Centisome position: 92.53

GC content: 45.53

Gene sequence:

>1017_bases
ATGTCCATTCTCGTTACAGGCGGTGCCGGCTACATTGGCAGCCACACTTGCGTTGAACTTTTAACAGAAGGCTATGACGT
TATCATAGTTGATAATTTTTCCAACAGCGGACCTGATACGGTTAACCGCATTGAAGAAATTACTAGCAAAAAAGTGAAGA
CTTATGACATTAATTTGCTTGATTCCTCTCGTTTAGAAACGGTTTTCGCTGAAAACAACATTGAAGCGGTGATCCATTTT
GCCGGTTTAAAAGCTGTCGGCGAATCGGTCGAAAAACCGCTTCATTATTATGAAACGAACATCGGCAGCACGATTCAATT
ATGCAAAACGATGGAAAAATATGGTGTATACAAACTCGTTTTCAGTTCATCAGCAACCGTGTACGGATTGCCTGAACAAG
TTCCAATTGAAGAAAACGCGCCGTTAAAAGCCGTCAACCCTTACGGCAATACCAAAATCATTATTGAGGACATGCTACGT
GATTTAGCGACTTCTAATAACAACTGGCGCATTTCACTACTACGCTATTTTAACCCAATCGGCGCCCATAAAAGCGGCCT
GATTGGCGAAGAGCCAAGCGGGATCCCAAATAATTTGATGCCTTATATTACCCAGGTTGCTGCCGGCGTGCGTGAACAAC
TGTCTGTTTTTGGCGATGATTACCCGACAAAAGATGGGACATGCATCCGCGACTACATCCATGTTGTTGACCTTGCTTTG
GGCCACTTGCAAGCGCTCAAAAAAATCGAAACATATACAGGTGTGCAAGCATATAACTTGGGAACAGGCACCGGCTACAG
CGTTCTTGAAGTGGTTGACGCCTTTGAAAAAGCGACTGGCATCACGATTCCGAAAAAAATCGGCCCCCGTCGTCCAGGTG
ATGCCCCTGTCAGCTATGCCGACCCCACGAAAGCAAGAACCGAACTTCAGTGGGAAGCAAAGCGGACGCTTATAGAAATG
TGTGAAGACTCTTGGCGTTGGCAAGTCCACCGCAAAGCACAGCTTGAAAGCAAGTAA

Upstream 100 bases:

>100_bases
TTTCCTCAAGATTGTTCGTTCTTTCTTCTATATTTTGTTTTTTGCATTTCTGGTATACTAGAGTGAATAACACTTACTTT
GTATACCGTGGAGGGATACT

Downstream 100 bases:

>100_bases
ATAAAGGTCAATCGTTGTTAAATGGAAATGGAGCCTTTCATAGGGAAGGCTCCATTTCCAGATTGAACCAAACCGCCTCA
ACCGAAAATAGCTTGAATAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSILVTGGAGYIGSHTCVELLTEGYDVIIVDNFSNSGPDTVNRIEEITSKKVKTYDINLLDSSRLETVFAENNIEAVIHF
AGLKAVGESVEKPLHYYETNIGSTIQLCKTMEKYGVYKLVFSSSATVYGLPEQVPIEENAPLKAVNPYGNTKIIIEDMLR
DLATSNNNWRISLLRYFNPIGAHKSGLIGEEPSGIPNNLMPYITQVAAGVREQLSVFGDDYPTKDGTCIRDYIHVVDLAL
GHLQALKKIETYTGVQAYNLGTGTGYSVLEVVDAFEKATGITIPKKIGPRRPGDAPVSYADPTKARTELQWEAKRTLIEM
CEDSWRWQVHRKAQLESK

Sequences:

>Translated_338_residues
MSILVTGGAGYIGSHTCVELLTEGYDVIIVDNFSNSGPDTVNRIEEITSKKVKTYDINLLDSSRLETVFAENNIEAVIHF
AGLKAVGESVEKPLHYYETNIGSTIQLCKTMEKYGVYKLVFSSSATVYGLPEQVPIEENAPLKAVNPYGNTKIIIEDMLR
DLATSNNNWRISLLRYFNPIGAHKSGLIGEEPSGIPNNLMPYITQVAAGVREQLSVFGDDYPTKDGTCIRDYIHVVDLAL
GHLQALKKIETYTGVQAYNLGTGTGYSVLEVVDAFEKATGITIPKKIGPRRPGDAPVSYADPTKARTELQWEAKRTLIEM
CEDSWRWQVHRKAQLESK
>Mature_337_residues
SILVTGGAGYIGSHTCVELLTEGYDVIIVDNFSNSGPDTVNRIEEITSKKVKTYDINLLDSSRLETVFAENNIEAVIHFA
GLKAVGESVEKPLHYYETNIGSTIQLCKTMEKYGVYKLVFSSSATVYGLPEQVPIEENAPLKAVNPYGNTKIIIEDMLRD
LATSNNNWRISLLRYFNPIGAHKSGLIGEEPSGIPNNLMPYITQVAAGVREQLSVFGDDYPTKDGTCIRDYIHVVDLALG
HLQALKKIETYTGVQAYNLGTGTGYSVLEVVDAFEKATGITIPKKIGPRRPGDAPVSYADPTKARTELQWEAKRTLIEMC
EDSWRWQVHRKAQLESK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=333, Percent_Identity=55.8558558558559, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI56118217, Length=333, Percent_Identity=55.8558558558559, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI189083684, Length=333, Percent_Identity=55.8558558558559, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI7657641, Length=272, Percent_Identity=24.2647058823529, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1786974, Length=329, Percent_Identity=51.3677811550152, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI48994969, Length=357, Percent_Identity=26.3305322128852, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788353, Length=350, Percent_Identity=24.8571428571429, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790049, Length=287, Percent_Identity=26.1324041811847, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=338, Percent_Identity=51.1834319526627, Blast_Score=355, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI71982038, Length=340, Percent_Identity=50.5882352941176, Blast_Score=352, Evalue=1e-97,
Organism=Saccharomyces cerevisiae, GI6319493, Length=334, Percent_Identity=53.5928143712575, Blast_Score=364, Evalue=1e-102,
Organism=Drosophila melanogaster, GI19923002, Length=336, Percent_Identity=53.2738095238095, Blast_Score=360, Evalue=1e-100,
Organism=Drosophila melanogaster, GI21356223, Length=317, Percent_Identity=25.5520504731861, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37425; Mature: 37294

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVTGGAGYIGSHTCVELLTEGYDVIIVDNFSNSGPDTVNRIEEITSKKVKTYDINLL
CEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEEC
DSSRLETVFAENNIEAVIHFAGLKAVGESVEKPLHYYETNIGSTIQLCKTMEKYGVYKLV
CCCHHHEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEE
FSSSATVYGLPEQVPIEENAPLKAVNPYGNTKIIIEDMLRDLATSNNNWRISLLRYFNPI
ECCCCEEEECCCCCCCCCCCCCEEECCCCCCEEEHHHHHHHHHCCCCCEEEEEEHHCCCC
GAHKSGLIGEEPSGIPNNLMPYITQVAAGVREQLSVFGDDYPTKDGTCIRDYIHVVDLAL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
GHLQALKKIETYTGVQAYNLGTGTGYSVLEVVDAFEKATGITIPKKIGPRRPGDAPVSYA
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCC
DPTKARTELQWEAKRTLIEMCEDSWRWQVHRKAQLESK
CCCCHHHHHHHHHHHHHHHHHHCCHHEEEEHHHCCCCC
>Mature Secondary Structure 
SILVTGGAGYIGSHTCVELLTEGYDVIIVDNFSNSGPDTVNRIEEITSKKVKTYDINLL
EEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCEEEEEEEEC
DSSRLETVFAENNIEAVIHFAGLKAVGESVEKPLHYYETNIGSTIQLCKTMEKYGVYKLV
CCCHHHEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEE
FSSSATVYGLPEQVPIEENAPLKAVNPYGNTKIIIEDMLRDLATSNNNWRISLLRYFNPI
ECCCCEEEECCCCCCCCCCCCCEEECCCCCCEEEHHHHHHHHHCCCCCEEEEEEHHCCCC
GAHKSGLIGEEPSGIPNNLMPYITQVAAGVREQLSVFGDDYPTKDGTCIRDYIHVVDLAL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
GHLQALKKIETYTGVQAYNLGTGTGYSVLEVVDAFEKATGITIPKKIGPRRPGDAPVSYA
HHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCC
DPTKARTELQWEAKRTLIEMCEDSWRWQVHRKAQLESK
CCCCHHHHHHHHHHHHHHHHHHCCHHEEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]