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The map label for this gene is yraN [H]

Identifier: 56965424

GI number: 56965424

Start: 3819790

End: 3820665

Strand: Direct

Name: yraN [H]

Synonym: ABC3662

Alternate gene names: 56965424

Gene position: 3819790-3820665 (Clockwise)

Preceding gene: 56965414

Following gene: 56965428

Centisome position: 88.75

GC content: 39.61

Gene sequence:

>876_bases
ATGAACGAAAAAGATTGGGAACTGTTGCAGACATTATATGAAATGAAAAACATAACGAAAGCGGCCGAAAAATTGTTTAT
TTCACAACCTGCCTTGACGTACAGACTAAGAAGTTTGGAAAATGAGTTTGGGGTTGAAATTGCCAAACGGGGAACGAAAA
GACTGCAGTTTACAAGCGAAGGCGAGTATTTAGTCGAATATTCAAGGAAAATGTTAAATGAATTAGCCAAAACAAAAGAC
CAACTGCTAAACATGGCCGGAAACATCCAAGGCCACTTGCGGATCGGTGTTTCCAGTCATTTCGCCCACTATCGATTACC
AACGATTTTAAAAGATTTTCTTGCGGTCTATCCCAATGTACAAGTAAACGTTACAACTGGCTGGAGTACAAAAATATCAC
AAAAACTAGAAAGAAAAGAAGTGCATATTGGCATTATCCGTGGAAGCTACGAATGGAAAGAACAAAGTATACTTCTTAAC
GAAGAAAATGTGTGTTTAATTTCAAAGAATAAGATTCATATGGGTGATCTCCCTTCTATTGGAAGGATATCCTATAAAAC
CGATCCAATCTTTGATAATATGATCAAAGACTGGTGGAACCATCATTTTAGCCAGCCACCAATGGTAACGATGGAAGTCG
ACCGTATCGAGACTTGCAAAGAAATGGTACGCAATGGCTTAGGATACGCAATCATCCCTCAAATTTCCCTTCGTCCGCAT
GACCAATTATACAACCGCATCCTTGCCATTGATAACCACCCACTATTAAGAAAAACGTGGTTAATCTATTCCAATTCCGC
ACTCGACCTTTCAGTCGTCAAAGCGTTTGTCCAATTCGTTACAACCCAATTGCGCCAGCAAGCACATTCGCTTTAA

Upstream 100 bases:

>100_bases
AGGTCATCTATTTTCTTCCCGGTCCAATATGATCCCTTCTTGTTTCTGCTTTTTTAAAGTAAAATGAAAGATATTTCAAA
AAACATTAGGGGAGGCCGCA

Downstream 100 bases:

>100_bases
TGGCTACGCCATTTTGCACTCTCCACACGGGAATGGTAGTTGCATTTATCCAAAAGACCTTTTACAAGAAGAAAATGGGT
TTGTTAGGAAAGGAATCAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNEKDWELLQTLYEMKNITKAAEKLFISQPALTYRLRSLENEFGVEIAKRGTKRLQFTSEGEYLVEYSRKMLNELAKTKD
QLLNMAGNIQGHLRIGVSSHFAHYRLPTILKDFLAVYPNVQVNVTTGWSTKISQKLERKEVHIGIIRGSYEWKEQSILLN
EENVCLISKNKIHMGDLPSIGRISYKTDPIFDNMIKDWWNHHFSQPPMVTMEVDRIETCKEMVRNGLGYAIIPQISLRPH
DQLYNRILAIDNHPLLRKTWLIYSNSALDLSVVKAFVQFVTTQLRQQAHSL

Sequences:

>Translated_291_residues
MNEKDWELLQTLYEMKNITKAAEKLFISQPALTYRLRSLENEFGVEIAKRGTKRLQFTSEGEYLVEYSRKMLNELAKTKD
QLLNMAGNIQGHLRIGVSSHFAHYRLPTILKDFLAVYPNVQVNVTTGWSTKISQKLERKEVHIGIIRGSYEWKEQSILLN
EENVCLISKNKIHMGDLPSIGRISYKTDPIFDNMIKDWWNHHFSQPPMVTMEVDRIETCKEMVRNGLGYAIIPQISLRPH
DQLYNRILAIDNHPLLRKTWLIYSNSALDLSVVKAFVQFVTTQLRQQAHSL
>Mature_291_residues
MNEKDWELLQTLYEMKNITKAAEKLFISQPALTYRLRSLENEFGVEIAKRGTKRLQFTSEGEYLVEYSRKMLNELAKTKD
QLLNMAGNIQGHLRIGVSSHFAHYRLPTILKDFLAVYPNVQVNVTTGWSTKISQKLERKEVHIGIIRGSYEWKEQSILLN
EENVCLISKNKIHMGDLPSIGRISYKTDPIFDNMIKDWWNHHFSQPPMVTMEVDRIETCKEMVRNGLGYAIIPQISLRPH
DQLYNRILAIDNHPLLRKTWLIYSNSALDLSVVKAFVQFVTTQLRQQAHSL

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=281, Percent_Identity=25.9786476868327, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787530, Length=238, Percent_Identity=25.6302521008403, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788296, Length=130, Percent_Identity=31.5384615384615, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790399, Length=146, Percent_Identity=27.3972602739726, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787806, Length=299, Percent_Identity=22.0735785953177, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367136, Length=242, Percent_Identity=24.7933884297521, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=264, Percent_Identity=22.7272727272727, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788481, Length=272, Percent_Identity=25, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789204, Length=245, Percent_Identity=23.265306122449, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33860; Mature: 33860

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKDWELLQTLYEMKNITKAAEKLFISQPALTYRLRSLENEFGVEIAKRGTKRLQFTSE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHCCCCEEEECCC
GEYLVEYSRKMLNELAKTKDQLLNMAGNIQGHLRIGVSSHFAHYRLPTILKDFLAVYPNV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCC
QVNVTTGWSTKISQKLERKEVHIGIIRGSYEWKEQSILLNEENVCLISKNKIHMGDLPSI
EEEEECCCCHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCCCEEEEECCEEECCCCCCC
GRISYKTDPIFDNMIKDWWNHHFSQPPMVTMEVDRIETCKEMVRNGLGYAIIPQISLRPH
CCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCEEEECCCCCCCH
DQLYNRILAIDNHPLLRKTWLIYSNSALDLSVVKAFVQFVTTQLRQQAHSL
HHHHHHHEEECCCCCHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNEKDWELLQTLYEMKNITKAAEKLFISQPALTYRLRSLENEFGVEIAKRGTKRLQFTSE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHCCCCEEEECCC
GEYLVEYSRKMLNELAKTKDQLLNMAGNIQGHLRIGVSSHFAHYRLPTILKDFLAVYPNV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCC
QVNVTTGWSTKISQKLERKEVHIGIIRGSYEWKEQSILLNEENVCLISKNKIHMGDLPSI
EEEEECCCCHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCCCEEEEECCEEECCCCCCC
GRISYKTDPIFDNMIKDWWNHHFSQPPMVTMEVDRIETCKEMVRNGLGYAIIPQISLRPH
CCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCEEEECCCCCCCH
DQLYNRILAIDNHPLLRKTWLIYSNSALDLSVVKAFVQFVTTQLRQQAHSL
HHHHHHHEEECCCCCHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9308178; 9384377 [H]