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The map label for this gene is ybfF [C]

Identifier: 56965198

GI number: 56965198

Start: 3564082

End: 3564993

Strand: Direct

Name: ybfF [C]

Synonym: ABC3436

Alternate gene names: 56965198

Gene position: 3564082-3564993 (Clockwise)

Preceding gene: 56965196

Following gene: 56965207

Centisome position: 82.81

GC content: 43.64

Gene sequence:

>912_bases
ATGGATGCTTGGAATGATTTTCAGTTATGCCAACTGAAGCATCGCTATGCTCACGTGAATGGGATTCAACTACACTATGT
TGAAGGAGGGGAGCAGCATTCTAATACGGTTGTCTTATTGCATGGCTTCCCACAAAGTTGGGTCTTATGGAGGTTCGTTA
TTCCCGATTTAGTAAAGCGTTATCGTGTACTCGCTGTCGATTTGAGAGGCTATGGGGATTCGGATAAACCAGAAGGAATA
GAAGGCTATACGAAAGCGAACATGGCCAAAGATATTTATGACCTTGTGACCCATTTACGATTAGAAAAAGTGACTTTGAT
TGGGCATGACCGTGGGGCTAGAGTAGCCAGAAGATTCGCCTTAGATTATCCTGACTATGTAGCAAGCCTTTGCCTCATCG
ATATTCTTCCTTTGGAATATGTTTATGACAACCTTTCTGCCTCGGAAGCTGCTAAAAAATATTGGCATTGGGTTTTTCAA
GTAGTCGCAGAGTTGCCTGAAGCGCTCATTGAAGGTCGGGAAGAGGTTTATCTTGGGGCTTTGTTTAAACGAACGCCCCA
TTTACTGGAGCAATTAAAAGCTGACGGAGTTTGGGATGAATACGTACGTATTTGGAAGCAACCAGGTGGTTTTCAAGCCG
CTCTGAACGATTATCGTGCGGCGCACAAGCTTGATTTACCGAACTATCGAGTAGAAAAAGAAATGAATAAAAACATCAAT
CAACCTTGTTTGCTGCTTTGGGGGGAAAACGGGAATTTGGCTGGTCAGCCTGTGCTTACGATATGGAAAGAAGTAGCGAC
GATGGTTACAGGGAAAGAGCTTGCTGGTTGTGGTCATTATGTTCCTGAAGAGCAGCCAGACGCTATGATGCAAGAGCTTG
TGCCATTTTTAGAAGACATTTATCAAACATAG

Upstream 100 bases:

>100_bases
ATGATCGATACCTTTAAATTTAATCATTTTAAATTATAAAGGAAAGGGCTTACAATGCAATTGTATTGCTATAAAGATAG
CAAAAGGAGGCGCTAGACAA

Downstream 100 bases:

>100_bases
CAGGCATAATCCATGAGAAACCTCATTTAGACGAATAGAAAAACTTGTCTCCAGGCTGCAACATGGAGCGCGACCATTGC
GCTCCATGTTTGAGGTTGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDAWNDFQLCQLKHRYAHVNGIQLHYVEGGEQHSNTVVLLHGFPQSWVLWRFVIPDLVKRYRVLAVDLRGYGDSDKPEGI
EGYTKANMAKDIYDLVTHLRLEKVTLIGHDRGARVARRFALDYPDYVASLCLIDILPLEYVYDNLSASEAAKKYWHWVFQ
VVAELPEALIEGREEVYLGALFKRTPHLLEQLKADGVWDEYVRIWKQPGGFQAALNDYRAAHKLDLPNYRVEKEMNKNIN
QPCLLLWGENGNLAGQPVLTIWKEVATMVTGKELAGCGHYVPEEQPDAMMQELVPFLEDIYQT

Sequences:

>Translated_303_residues
MDAWNDFQLCQLKHRYAHVNGIQLHYVEGGEQHSNTVVLLHGFPQSWVLWRFVIPDLVKRYRVLAVDLRGYGDSDKPEGI
EGYTKANMAKDIYDLVTHLRLEKVTLIGHDRGARVARRFALDYPDYVASLCLIDILPLEYVYDNLSASEAAKKYWHWVFQ
VVAELPEALIEGREEVYLGALFKRTPHLLEQLKADGVWDEYVRIWKQPGGFQAALNDYRAAHKLDLPNYRVEKEMNKNIN
QPCLLLWGENGNLAGQPVLTIWKEVATMVTGKELAGCGHYVPEEQPDAMMQELVPFLEDIYQT
>Mature_303_residues
MDAWNDFQLCQLKHRYAHVNGIQLHYVEGGEQHSNTVVLLHGFPQSWVLWRFVIPDLVKRYRVLAVDLRGYGDSDKPEGI
EGYTKANMAKDIYDLVTHLRLEKVTLIGHDRGARVARRFALDYPDYVASLCLIDILPLEYVYDNLSASEAAKKYWHWVFQ
VVAELPEALIEGREEVYLGALFKRTPHLLEQLKADGVWDEYVRIWKQPGGFQAALNDYRAAHKLDLPNYRVEKEMNKNIN
QPCLLLWGENGNLAGQPVLTIWKEVATMVTGKELAGCGHYVPEEQPDAMMQELVPFLEDIYQT

Specific function: Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has low activity towards chloroacetate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=286, Percent_Identity=30.4195804195804, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI13376164, Length=286, Percent_Identity=30.4195804195804, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI218777837, Length=299, Percent_Identity=29.7658862876254, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27597073, Length=316, Percent_Identity=26.8987341772152, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI189027141, Length=306, Percent_Identity=27.4509803921569, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562298, Length=297, Percent_Identity=27.6094276094276, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17554012, Length=287, Percent_Identity=26.1324041811847, Blast_Score=118, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6324392, Length=118, Percent_Identity=30.5084745762712, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646055, Length=188, Percent_Identity=27.1276595744681, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 34885; Mature: 34885

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAWNDFQLCQLKHRYAHVNGIQLHYVEGGEQHSNTVVLLHGFPQSWVLWRFVIPDLVKR
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
YRVLAVDLRGYGDSDKPEGIEGYTKANMAKDIYDLVTHLRLEKVTLIGHDRGARVARRFA
HHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHH
LDYPDYVASLCLIDILPLEYVYDNLSASEAAKKYWHWVFQVVAELPEALIEGREEVYLGA
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LFKRTPHLLEQLKADGVWDEYVRIWKQPGGFQAALNDYRAAHKLDLPNYRVEKEMNKNIN
HHHCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
QPCLLLWGENGNLAGQPVLTIWKEVATMVTGKELAGCGHYVPEEQPDAMMQELVPFLEDI
CCEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
YQT
HCC
>Mature Secondary Structure
MDAWNDFQLCQLKHRYAHVNGIQLHYVEGGEQHSNTVVLLHGFPQSWVLWRFVIPDLVKR
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
YRVLAVDLRGYGDSDKPEGIEGYTKANMAKDIYDLVTHLRLEKVTLIGHDRGARVARRFA
HHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHH
LDYPDYVASLCLIDILPLEYVYDNLSASEAAKKYWHWVFQVVAELPEALIEGREEVYLGA
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LFKRTPHLLEQLKADGVWDEYVRIWKQPGGFQAALNDYRAAHKLDLPNYRVEKEMNKNIN
HHHCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
QPCLLLWGENGNLAGQPVLTIWKEVATMVTGKELAGCGHYVPEEQPDAMMQELVPFLEDI
CCEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
YQT
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA