Click here to switch to the map view.

The map label for this gene is desR [H]

Identifier: 56965096

GI number: 56965096

Start: 3460089

End: 3460694

Strand: Direct

Name: desR [H]

Synonym: ABC3334

Alternate gene names: 56965096

Gene position: 3460089-3460694 (Clockwise)

Preceding gene: 56965095

Following gene: 56965097

Centisome position: 80.39

GC content: 48.68

Gene sequence:

>606_bases
ATGATTCAAATATTAATTGCTGAAGATCAAACGATTTTGCGCAATGCGCTTGAGTCACTGCTTAACTTAGAAAAAGACAT
TCATGTAGCCGGAGCCGTTCCTAGCGGCGCTTCAGTCCGCTCGTTTCCCGGCCTTTGGGAGCTAGATTTGCTTCTCATGG
ATATCGAAATGCCTGATGGGACAGGGCTCGAGACAGCGAAATACATGAAACAGCATGGCTTCAGAGGGAAAATTGCGCTG
TTGACGACCTTTTCGCGGCCAGGCTATATTGAACAAGCGATGAAACTTGGCGTGGACGGCTATTTGCTTAAAGATGACCC
GATTGATCAATTGATTGTAGCGATCCGCCGCATTGTAGCTGGCGAACACGTCATCTCTCCGGCCCTTAGCAACATGTTGT
TTCGTTTGCAGCCCAACCCATTAAATGACCGTGAACAAGAGATGCTCCGGCGAGTGCGCAATGGCGAAAGCACAGAAACG
ATCGCCTCTGCCATGCACCTTTCCCTCGGAACAGTCCGCAACTATTTATCATCTGCGATGCAAAAACTTGAAACGACTAA
CCGCCACGACGCATTGCGGATCGCAGAAGAGAAAGGATGGATATAA

Upstream 100 bases:

>100_bases
GCATGCGCCTCGTTGGCGGCACATGTTTATGGGAAAGCGGTAGCTCAGGCACAACGGTTACGTTGACCGTGCCAACTTGA
CACGTAAAAGGAGAAGGAAA

Downstream 100 bases:

>100_bases
GACATGCATGCAATGGAAGGAATTATCGAATTTGCCGCACCCCTTTTTATTGCAATGGAACTTGCATCGCTCGTTTGCCT
GCTTTTGTTTGGCGTGGTCC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MIQILIAEDQTILRNALESLLNLEKDIHVAGAVPSGASVRSFPGLWELDLLLMDIEMPDGTGLETAKYMKQHGFRGKIAL
LTTFSRPGYIEQAMKLGVDGYLLKDDPIDQLIVAIRRIVAGEHVISPALSNMLFRLQPNPLNDREQEMLRRVRNGESTET
IASAMHLSLGTVRNYLSSAMQKLETTNRHDALRIAEEKGWI

Sequences:

>Translated_201_residues
MIQILIAEDQTILRNALESLLNLEKDIHVAGAVPSGASVRSFPGLWELDLLLMDIEMPDGTGLETAKYMKQHGFRGKIAL
LTTFSRPGYIEQAMKLGVDGYLLKDDPIDQLIVAIRRIVAGEHVISPALSNMLFRLQPNPLNDREQEMLRRVRNGESTET
IASAMHLSLGTVRNYLSSAMQKLETTNRHDALRIAEEKGWI
>Mature_201_residues
MIQILIAEDQTILRNALESLLNLEKDIHVAGAVPSGASVRSFPGLWELDLLLMDIEMPDGTGLETAKYMKQHGFRGKIAL
LTTFSRPGYIEQAMKLGVDGYLLKDDPIDQLIVAIRRIVAGEHVISPALSNMLFRLQPNPLNDREQEMLRRVRNGESTET
IASAMHLSLGTVRNYLSSAMQKLETTNRHDALRIAEEKGWI

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=188, Percent_Identity=29.2553191489362, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=28.2051282051282, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788222, Length=192, Percent_Identity=25.5208333333333, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787473, Length=198, Percent_Identity=28.2828282828283, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22491; Mature: 22491

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQILIAEDQTILRNALESLLNLEKDIHVAGAVPSGASVRSFPGLWELDLLLMDIEMPDG
CEEEEEECCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCEEEEEEEEEECCCC
TGLETAKYMKQHGFRGKIALLTTFSRPGYIEQAMKLGVDGYLLKDDPIDQLIVAIRRIVA
CCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHH
GEHVISPALSNMLFRLQPNPLNDREQEMLRRVRNGESTETIASAMHLSLGTVRNYLSSAM
CHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
QKLETTNRHDALRIAEEKGWI
HHHHHCCCHHHHEEHHCCCCC
>Mature Secondary Structure
MIQILIAEDQTILRNALESLLNLEKDIHVAGAVPSGASVRSFPGLWELDLLLMDIEMPDG
CEEEEEECCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCEEEEEEEEEECCCC
TGLETAKYMKQHGFRGKIALLTTFSRPGYIEQAMKLGVDGYLLKDDPIDQLIVAIRRIVA
CCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHH
GEHVISPALSNMLFRLQPNPLNDREQEMLRRVRNGESTETIASAMHLSLGTVRNYLSSAM
CHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
QKLETTNRHDALRIAEEKGWI
HHHHHCCCHHHHEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]