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The map label for this gene is yhcZ [H]

Identifier: 56964906

GI number: 56964906

Start: 3269105

End: 3269764

Strand: Direct

Name: yhcZ [H]

Synonym: ABC3142

Alternate gene names: 56964906

Gene position: 3269105-3269764 (Clockwise)

Preceding gene: 56964905

Following gene: 56964910

Centisome position: 75.96

GC content: 47.42

Gene sequence:

>660_bases
ATGAGAATTTTGCTAGCTGACGACCACCATGTTGTCCGTAAAGGGCTTGCCTATTTCTTAGAAGCCCATCCCGACATTGA
GATTGTTGCTGAAGCAAGCAATGGCGAAGAAGCGGTAGCATTGTACGAACGCCACCGCCCCGACATTCTGTTAATGGACA
TTGACATGCCAGTCATGGATGGTATTCAGGCGACACACGTCATATTACGCAATCATCCACAGGCAAAAGTGTTTATGTTG
TCAGGCTATGGAGAAAAAGACTTTGTGATCCAAGCACTGCAAGCAGGAGCTTGTGGCTATCAGCTAAAAGATGTGGAACC
TGATGTGTTGATCTACACGATTCAGGCCGCTAATAGCGGGGAACTTCCTCTTGACCCCCGGATTATGAAGCATGTGCTTA
CCCATGTCGCGCGCTCGGCCAATTCTGTCGCTGACAAAGTGAACCGTTTGACAGACAGGGAAGTCGACGTGCTGAAAGAA
ATTAGCACTGGCAAGAGCAATAAAGAAATCGCAGCTGCGCTGTTTATTTCCGAGAAAACGGTAAAGACCCATGTTTCCAA
TCTCCTTGGCAAATTGGAGCTTCAGGATCGGACGCAAGCTGCGTTGTTTGCGATCCAAGCAGGGATTGCTAAGCCCATTT
CATTTTTGGATGAACAATAA

Upstream 100 bases:

>100_bases
AACGGGCAAAAGAACTAGGCGGGCAGGCGTTATTGATATCAGCACCAGGGAGTGGCACGACGTGGGAAATTCGCTTTCCT
GATAAAAAGGGGGAAAAGGA

Downstream 100 bases:

>100_bases
ATTCCACTTCTTCCCCATTTGGATGGACAAAATAAAGCGACTCTTCGTCTCGATTAAGGAGAAACCGCTCGGTAAGCGCA
AAGCCGCGTTTTTTGGTATT

Product: two-component response regulator of extracellular proteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MRILLADDHHVVRKGLAYFLEAHPDIEIVAEASNGEEAVALYERHRPDILLMDIDMPVMDGIQATHVILRNHPQAKVFML
SGYGEKDFVIQALQAGACGYQLKDVEPDVLIYTIQAANSGELPLDPRIMKHVLTHVARSANSVADKVNRLTDREVDVLKE
ISTGKSNKEIAAALFISEKTVKTHVSNLLGKLELQDRTQAALFAIQAGIAKPISFLDEQ

Sequences:

>Translated_219_residues
MRILLADDHHVVRKGLAYFLEAHPDIEIVAEASNGEEAVALYERHRPDILLMDIDMPVMDGIQATHVILRNHPQAKVFML
SGYGEKDFVIQALQAGACGYQLKDVEPDVLIYTIQAANSGELPLDPRIMKHVLTHVARSANSVADKVNRLTDREVDVLKE
ISTGKSNKEIAAALFISEKTVKTHVSNLLGKLELQDRTQAALFAIQAGIAKPISFLDEQ
>Mature_219_residues
MRILLADDHHVVRKGLAYFLEAHPDIEIVAEASNGEEAVALYERHRPDILLMDIDMPVMDGIQATHVILRNHPQAKVFML
SGYGEKDFVIQALQAGACGYQLKDVEPDVLIYTIQAANSGELPLDPRIMKHVLTHVARSANSVADKVNRLTDREVDVLKE
ISTGKSNKEIAAALFISEKTVKTHVSNLLGKLELQDRTQAALFAIQAGIAKPISFLDEQ

Specific function: Member of the two-component regulatory system yhcY/yhcZ [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=35.9223300970874, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787473, Length=208, Percent_Identity=38.4615384615385, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=30.3317535545024, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=33.5, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1786747, Length=193, Percent_Identity=31.0880829015544, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=30.5825242718447, Blast_Score=90, Evalue=9e-20,
Organism=Escherichia coli, GI1787277, Length=106, Percent_Identity=36.7924528301887, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082052, Length=106, Percent_Identity=33.9622641509434, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=34.7457627118644, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24213; Mature: 24213

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLADDHHVVRKGLAYFLEAHPDIEIVAEASNGEEAVALYERHRPDILLMDIDMPVMD
CEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCCEEEEECCCHHHC
GIQATHVILRNHPQAKVFMLSGYGEKDFVIQALQAGACGYQLKDVEPDVLIYTIQAANSG
CHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCEECCCCCCEEEEEEEECCCC
ELPLDPRIMKHVLTHVARSANSVADKVNRLTDREVDVLKEISTGKSNKEIAAALFISEKT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEECHHH
VKTHVSNLLGKLELQDRTQAALFAIQAGIAKPISFLDEQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRILLADDHHVVRKGLAYFLEAHPDIEIVAEASNGEEAVALYERHRPDILLMDIDMPVMD
CEEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHCCCCCEEEEECCCHHHC
GIQATHVILRNHPQAKVFMLSGYGEKDFVIQALQAGACGYQLKDVEPDVLIYTIQAANSG
CHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCEECCCCCCEEEEEEEECCCC
ELPLDPRIMKHVLTHVARSANSVADKVNRLTDREVDVLKEISTGKSNKEIAAALFISEKT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEECHHH
VKTHVSNLLGKLELQDRTQAALFAIQAGIAKPISFLDEQ
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]