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The map label for this gene is yhcY [H]

Identifier: 56964905

GI number: 56964905

Start: 3267996

End: 3269108

Strand: Direct

Name: yhcY [H]

Synonym: ABC3141

Alternate gene names: 56964905

Gene position: 3267996-3269108 (Clockwise)

Preceding gene: 56964902

Following gene: 56964906

Centisome position: 75.93

GC content: 46.09

Gene sequence:

>1113_bases
ATGAGCCATCTCCACACGCTAAAACAAATTTCCCAGACATTAAATGCCGAGAATGACTTAAAACGTATGCTTGATAACGT
GTTGCACACATTGCTTGCGGAGCTCGATTTTTCGAGCGGCTGGATTTTTTTAATTGACCAAATGGGAAACCATACCCTTT
ATGCTGCAAGCGGCATTCCGCCAGGACTTTCACGAAAAAATTGCACCCCGTTAAAAGAGGGCGGTTGCTGGTGCAAAAAC
CAATTCCTACATGGGACATTGGAACGGGCTGTTAATATGATTGAATGCCAACGTTTGGAACGGGCGATTGAACGAGGCTG
GGGCGAAACAAACGGCATTACCCATCACGCTACCGTTCCCATCTATGCAGGTGAAGAGCCACTTGGCATCTTAAACGTGG
CCCATCCCCAAAAACACCATTATGCACAAGATGAACTGGAGTTGTTAGAACTCATTGCTTTGCAAATCGGAACAGCGATC
AAACGTGTGGAGCTTGTTGCCTTTGAAGCGGAACAGGCTGAATTGAATGAACGGCAACGCCTATCCCAGGATCTCCATGA
TTCAGTCAACCAATTGCTTTTTTCCGTTAACATGACGTTGCAAGGGATGGCTATTCGGACAAAAGACGAGGAAATGAAAG
AGAAAATGTCTGACGTTTCCAAATTAGTTAGCGCCGCATTAGGTGAGCTTCGGGCCATTATACGAGGCCATTCAGGAGAG
GAATTAGAGGCTGGACTGGCACAAGCAGTCGAACAGTACAGCCGCTTAATCGGCATTTCTGTACGCCTCCTCCTTCCTAC
TGAGGTTGACTGGCCAGCAAAAACAGAGTTAGCTACTTACCGAATCATCCAAGAAGCATTAAACAATTGTAAAAAACATG
CTGGCGTGAAAGAAGCAACGATTTCTTTAACAAAAGCACAAGGGGAATGGCTTTTAACCATTTCTGATCAAGGCGAAGGC
TTTGAAACAAACCATGTTAGCCGCAGACAAGGACTTGATTCAATCCGCAAACGGGCAAAAGAACTAGGCGGGCAGGCGTT
ATTGATATCAGCACCAGGGAGTGGCACGACGTGGGAAATTCGCTTTCCTGATAAAAAGGGGGAAAAGGAATGA

Upstream 100 bases:

>100_bases
TGCTGTTTGTTTAAACATCATAAACGCACGGCAAAGAACTCCTATGCTAAACTAGAAAGAGGAATTCACACTGTACCTTT
TCACCAAAGGAGTTTATATA

Downstream 100 bases:

>100_bases
GAATTTTGCTAGCTGACGACCACCATGTTGTCCGTAAAGGGCTTGCCTATTTCTTAGAAGCCCATCCCGACATTGAGATT
GTTGCTGAAGCAAGCAATGG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSHLHTLKQISQTLNAENDLKRMLDNVLHTLLAELDFSSGWIFLIDQMGNHTLYAASGIPPGLSRKNCTPLKEGGCWCKN
QFLHGTLERAVNMIECQRLERAIERGWGETNGITHHATVPIYAGEEPLGILNVAHPQKHHYAQDELELLELIALQIGTAI
KRVELVAFEAEQAELNERQRLSQDLHDSVNQLLFSVNMTLQGMAIRTKDEEMKEKMSDVSKLVSAALGELRAIIRGHSGE
ELEAGLAQAVEQYSRLIGISVRLLLPTEVDWPAKTELATYRIIQEALNNCKKHAGVKEATISLTKAQGEWLLTISDQGEG
FETNHVSRRQGLDSIRKRAKELGGQALLISAPGSGTTWEIRFPDKKGEKE

Sequences:

>Translated_370_residues
MSHLHTLKQISQTLNAENDLKRMLDNVLHTLLAELDFSSGWIFLIDQMGNHTLYAASGIPPGLSRKNCTPLKEGGCWCKN
QFLHGTLERAVNMIECQRLERAIERGWGETNGITHHATVPIYAGEEPLGILNVAHPQKHHYAQDELELLELIALQIGTAI
KRVELVAFEAEQAELNERQRLSQDLHDSVNQLLFSVNMTLQGMAIRTKDEEMKEKMSDVSKLVSAALGELRAIIRGHSGE
ELEAGLAQAVEQYSRLIGISVRLLLPTEVDWPAKTELATYRIIQEALNNCKKHAGVKEATISLTKAQGEWLLTISDQGEG
FETNHVSRRQGLDSIRKRAKELGGQALLISAPGSGTTWEIRFPDKKGEKE
>Mature_369_residues
SHLHTLKQISQTLNAENDLKRMLDNVLHTLLAELDFSSGWIFLIDQMGNHTLYAASGIPPGLSRKNCTPLKEGGCWCKNQ
FLHGTLERAVNMIECQRLERAIERGWGETNGITHHATVPIYAGEEPLGILNVAHPQKHHYAQDELELLELIALQIGTAIK
RVELVAFEAEQAELNERQRLSQDLHDSVNQLLFSVNMTLQGMAIRTKDEEMKEKMSDVSKLVSAALGELRAIIRGHSGEE
LEAGLAQAVEQYSRLIGISVRLLLPTEVDWPAKTELATYRIIQEALNNCKKHAGVKEATISLTKAQGEWLLTISDQGEGF
ETNHVSRRQGLDSIRKRAKELGGQALLISAPGSGTTWEIRFPDKKGEKE

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation [H]

COG id: COG2203

COG function: function code T; FOG: GAF domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=251, Percent_Identity=26.6932270916335, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788812, Length=207, Percent_Identity=28.5024154589372, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41246; Mature: 41114

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLHTLKQISQTLNAENDLKRMLDNVLHTLLAELDFSSGWIFLIDQMGNHTLYAASGIP
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCC
PGLSRKNCTPLKEGGCWCKNQFLHGTLERAVNMIECQRLERAIERGWGETNGITHHATVP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
IYAGEEPLGILNVAHPQKHHYAQDELELLELIALQIGTAIKRVELVAFEAEQAELNERQR
EEECCCCCEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHH
LSQDLHDSVNQLLFSVNMTLQGMAIRTKDEEMKEKMSDVSKLVSAALGELRAIIRGHSGE
HHHHHHHHHHHHHHHHCCEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ELEAGLAQAVEQYSRLIGISVRLLLPTEVDWPAKTELATYRIIQEALNNCKKHAGVKEAT
HHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
ISLTKAQGEWLLTISDQGEGFETNHVSRRQGLDSIRKRAKELGGQALLISAPGSGTTWEI
EEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEE
RFPDKKGEKE
ECCCCCCCCC
>Mature Secondary Structure 
SHLHTLKQISQTLNAENDLKRMLDNVLHTLLAELDFSSGWIFLIDQMGNHTLYAASGIP
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCC
PGLSRKNCTPLKEGGCWCKNQFLHGTLERAVNMIECQRLERAIERGWGETNGITHHATVP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
IYAGEEPLGILNVAHPQKHHYAQDELELLELIALQIGTAIKRVELVAFEAEQAELNERQR
EEECCCCCEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHH
LSQDLHDSVNQLLFSVNMTLQGMAIRTKDEEMKEKMSDVSKLVSAALGELRAIIRGHSGE
HHHHHHHHHHHHHHHHCCEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ELEAGLAQAVEQYSRLIGISVRLLLPTEVDWPAKTELATYRIIQEALNNCKKHAGVKEAT
HHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
ISLTKAQGEWLLTISDQGEGFETNHVSRRQGLDSIRKRAKELGGQALLISAPGSGTTWEI
EEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEE
RFPDKKGEKE
ECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]