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The map label for this gene is nrdF [H]

Identifier: 56964873

GI number: 56964873

Start: 3236507

End: 3237511

Strand: Direct

Name: nrdF [H]

Synonym: ABC3109

Alternate gene names: 56964873

Gene position: 3236507-3237511 (Clockwise)

Preceding gene: 56964872

Following gene: 56964874

Centisome position: 75.2

GC content: 43.08

Gene sequence:

>1005_bases
ATGACGCACGTCTACGATGCGGCCAACTGGTCCAAGCATGAAGATGATTTTACGCAAATGTTTTATAACCAAAACGTCAA
ACAGTTTTGGCTTCCCGAGGAAGTCGCCTTAAATGGCGACCTTCTCACGTGGAAGTATTTGACGCCTGCCGAAAAAGACA
CGTATATGAAAGTGCTTGCCGGCTTGACGTTGCTCGACACCGAACAAGGAAACACTGGCATGCCTCTTGTGGCAGAACAC
GTCCAAGGCCACCAACGCAAAGCGGTTTTGAACTTTATGGCAATGATGGAAAACGCCGTCCATGCCAAGTCTTATTCAAA
CATTTTCATGACGCTTGCTACATCAGAAGAAATCAATGATTTGTTTGAATGGGTCAAAGTCAACCCCCGCCTCCAAAAAA
AGGCCAATACAATCGTCTCGATTTACAAAGACATTAAACGCGGCGACGACATTTCTCTTTTTAAAGCACTAGTCGCTTCT
GTCTACTTAGAAAGCTTTTTGTTCTACAGCGGTTTCTACTACCCGCTTTATTTCTATGGCCAAGGAAAGTTGATGCAAAG
CGGTGAAATTATTAACCTCATTCTTCGCGATGAAGCAATCCATGGCGTATACATTGGGCTGCTGGCACAAGAGATTTACA
ACAAGCAATCTCCTGATACACAAAAGGAACTGCACCAATTTGCGATTGAGCTTTTAGATGAACTGTATAAAAATGAGCTC
CTCTATACGGAAGATCTGTATGATCAAGTGGGGCTTTCCCATGATGTAAAAAAATTCATTCGCTACAATGCCAATAAAGC
GTTAATGAACCTTGGCTTTGATCCTTATTTTGAAGACGAGGACATCAACCCGATCGTCCTCAATGGACTGAATACAAAAA
CGAAGTCACATGACTTTTTCTCGATGAAAGGAAACGGCTACAAAAAAGCAACGGTTGAACCCCTCCGTGATGAGGATTTC
TTCTTTCCAGAAGCAGAGGAAAAAGCAAAGCAAGAGCAGCGTTAA

Upstream 100 bases:

>100_bases
AACCCTTTACTACGCGCGCACAAAAGATACAGGGCAAGACAACTGCCTTTCTTGTGTCGTTTAACAAAGTTTAAATGCAA
CCTAAAAAGGAGAGTGCCTA

Downstream 100 bases:

>100_bases
TCGTGGGTTATCGACCTTGTCGATAACCTTCCAAGAGCAGGATGAATCGCCTGCTCTTCCTTTTTGCTTTTCGCAAAGTT
AAAAAAATCCTCTTGCTTTG

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTHVYDAANWSKHEDDFTQMFYNQNVKQFWLPEEVALNGDLLTWKYLTPAEKDTYMKVLAGLTLLDTEQGNTGMPLVAEH
VQGHQRKAVLNFMAMMENAVHAKSYSNIFMTLATSEEINDLFEWVKVNPRLQKKANTIVSIYKDIKRGDDISLFKALVAS
VYLESFLFYSGFYYPLYFYGQGKLMQSGEIINLILRDEAIHGVYIGLLAQEIYNKQSPDTQKELHQFAIELLDELYKNEL
LYTEDLYDQVGLSHDVKKFIRYNANKALMNLGFDPYFEDEDINPIVLNGLNTKTKSHDFFSMKGNGYKKATVEPLRDEDF
FFPEAEEKAKQEQR

Sequences:

>Translated_334_residues
MTHVYDAANWSKHEDDFTQMFYNQNVKQFWLPEEVALNGDLLTWKYLTPAEKDTYMKVLAGLTLLDTEQGNTGMPLVAEH
VQGHQRKAVLNFMAMMENAVHAKSYSNIFMTLATSEEINDLFEWVKVNPRLQKKANTIVSIYKDIKRGDDISLFKALVAS
VYLESFLFYSGFYYPLYFYGQGKLMQSGEIINLILRDEAIHGVYIGLLAQEIYNKQSPDTQKELHQFAIELLDELYKNEL
LYTEDLYDQVGLSHDVKKFIRYNANKALMNLGFDPYFEDEDINPIVLNGLNTKTKSHDFFSMKGNGYKKATVEPLRDEDF
FFPEAEEKAKQEQR
>Mature_333_residues
THVYDAANWSKHEDDFTQMFYNQNVKQFWLPEEVALNGDLLTWKYLTPAEKDTYMKVLAGLTLLDTEQGNTGMPLVAEHV
QGHQRKAVLNFMAMMENAVHAKSYSNIFMTLATSEEINDLFEWVKVNPRLQKKANTIVSIYKDIKRGDDISLFKALVASV
YLESFLFYSGFYYPLYFYGQGKLMQSGEIINLILRDEAIHGVYIGLLAQEIYNKQSPDTQKELHQFAIELLDELYKNELL
YTEDLYDQVGLSHDVKKFIRYNANKALMNLGFDPYFEDEDINPIVLNGLNTKTKSHDFFSMKGNGYKKATVEPLRDEDFF
FPEAEEKAKQEQR

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Homo sapiens, GI42544136, Length=300, Percent_Identity=26.3333333333333, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI289177074, Length=300, Percent_Identity=26.3333333333333, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4557845, Length=303, Percent_Identity=24.7524752475248, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI260064013, Length=303, Percent_Identity=24.7524752475248, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789031, Length=319, Percent_Identity=44.8275862068966, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI1788567, Length=313, Percent_Identity=22.0447284345048, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322434, Length=296, Percent_Identity=23.9864864864865, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 38789; Mature: 38658

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00368 RIBORED_SMALL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHVYDAANWSKHEDDFTQMFYNQNVKQFWLPEEVALNGDLLTWKYLTPAEKDTYMKVLA
CCCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCHHHEECCCEEEEEECCCCCHHHHHHHHH
GLTLLDTEQGNTGMPLVAEHVQGHQRKAVLNFMAMMENAVHAKSYSNIFMTLATSEEIND
CCCEEECCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHH
LFEWVKVNPRLQKKANTIVSIYKDIKRGDDISLFKALVASVYLESFLFYSGFYYPLYFYG
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
QGKLMQSGEIINLILRDEAIHGVYIGLLAQEIYNKQSPDTQKELHQFAIELLDELYKNEL
CCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
LYTEDLYDQVGLSHDVKKFIRYNANKALMNLGFDPYFEDEDINPIVLNGLNTKTKSHDFF
EEHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEE
SMKGNGYKKATVEPLRDEDFFFPEAEEKAKQEQR
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
THVYDAANWSKHEDDFTQMFYNQNVKQFWLPEEVALNGDLLTWKYLTPAEKDTYMKVLA
CCCCCCCCCCCCHHHHHHHHHHCCCHHHCCCHHHEECCCEEEEEECCCCCHHHHHHHHH
GLTLLDTEQGNTGMPLVAEHVQGHQRKAVLNFMAMMENAVHAKSYSNIFMTLATSEEIND
CCCEEECCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHH
LFEWVKVNPRLQKKANTIVSIYKDIKRGDDISLFKALVASVYLESFLFYSGFYYPLYFYG
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
QGKLMQSGEIINLILRDEAIHGVYIGLLAQEIYNKQSPDTQKELHQFAIELLDELYKNEL
CCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
LYTEDLYDQVGLSHDVKKFIRYNANKALMNLGFDPYFEDEDINPIVLNGLNTKTKSHDFF
EEHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEE
SMKGNGYKKATVEPLRDEDFFFPEAEEKAKQEQR
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969495; 9384377 [H]