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The map label for this gene is ykvY [H]

Identifier: 56964497

GI number: 56964497

Start: 2866911

End: 2868020

Strand: Direct

Name: ykvY [H]

Synonym: ABC2732

Alternate gene names: 56964497

Gene position: 2866911-2868020 (Clockwise)

Preceding gene: 56964493

Following gene: 56964508

Centisome position: 66.61

GC content: 47.39

Gene sequence:

>1110_bases
TTGAAATTGGAACGGCTGCAAACATTGCAAAGGCAAATGGGAGAAAAGCAAGCTTGGTTTGCGTTTATAACAAGCAAAGA
AAATGTCTTTTATTTAACCGGTTACCGTACGGACCCCCATGAACGCCTCATTGCCTTTTTTGTTTTTCCAAATAGCCATT
TTCTTGTTGTTCCTAAAATGGAAGAAAGCATGGTCAGAAAAGCTGGATACGAAGGCGATATTCTTTCATATAGTGATAAT
GAAAATGTTTGGGAAAACATCTATGCCCGCATTCCCGAGCACGAGCCCCGTAACTTGCCACTTATATGTGTGGAAGAACG
GCTTGTCTCTTTTGAACGGATTCGCGCTTTACAAGCCCTTGATAAACAGGTTTCGTTTACTGACTGTGAAGGACTTTTAA
TGGAGCAGCGCCTTCAGAAAACGAATGAAGAACTGCAAACATTGCGTGCTGCCGCTGCTTTTGCTGATAGAGGGGTAGAG
TTAGGCGTAGCCGCATTAAAAACAGGCGTAACCGAAATGGAAGTCGTCGCGGCGATTGAATATGGCCTGAAACAACAAGG
CATCCGGGAAATGTCATTCCAGACAACCGTCCTCTTTGGCGACCATGCGAGCGCACCACATGGAAAGCCAGGCAATCGCC
AATTGCAAGAAGGCGAGTTTGTCCTTTTTGACCTTGGCGTCGTTTTAGAGGGCTACTGCTCCGACATTACTAGGACCGTT
GCCTACGGAAACGTTTCCGAACAGGAGGCCACTATTTACCATACAGTCCTTAAAGCGCAAGAAGCGGCGCTCGCTGCTGC
GAAGCCAGGTGCAGTCATTGGCGCTGTTGACCAAGCTGCACGCCATGTGATCACAGAAGCTGGCTATGGCGCGTTTTTTC
CACACCGACTTGGACACGGGTTAGGCATTGATGTACATGAGTCTCCCTCCATGCACCAAGACAACCAAAACCATTTAAAA
GAACGGATGACCTTTACAGTAGAACCTGGCATCTACATACCAGATCGTTGCGGTGTACGAATTGAAGACGATGTTGTTAT
TACAGCCGCTGGGTGCGAGGTAATGACAAGCTACCCGAAAACGCTGGACCCTGTGCCTGTTCGCTTATAA

Upstream 100 bases:

>100_bases
AAGCGCTCCTTTCGAATGTTTGTCTCTTTTTGATTTATAGCCGAATTTCTTTCGACTAAAACTATTTTACCGTATACTTA
AAGAAAGGAGGAGGATTCAT

Downstream 100 bases:

>100_bases
CCGCTCTGTCCAGCTCGTAAAAACGCAAAGTGGCCTTCTCCTCGCAGGCCACTTTGCTTTACCCTTTTTTATTCGCTTAC
TTTGTCCATAACCATGTAAA

Product: Xaa-Pro dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MKLERLQTLQRQMGEKQAWFAFITSKENVFYLTGYRTDPHERLIAFFVFPNSHFLVVPKMEESMVRKAGYEGDILSYSDN
ENVWENIYARIPEHEPRNLPLICVEERLVSFERIRALQALDKQVSFTDCEGLLMEQRLQKTNEELQTLRAAAAFADRGVE
LGVAALKTGVTEMEVVAAIEYGLKQQGIREMSFQTTVLFGDHASAPHGKPGNRQLQEGEFVLFDLGVVLEGYCSDITRTV
AYGNVSEQEATIYHTVLKAQEAALAAAKPGAVIGAVDQAARHVITEAGYGAFFPHRLGHGLGIDVHESPSMHQDNQNHLK
ERMTFTVEPGIYIPDRCGVRIEDDVVITAAGCEVMTSYPKTLDPVPVRL

Sequences:

>Translated_369_residues
MKLERLQTLQRQMGEKQAWFAFITSKENVFYLTGYRTDPHERLIAFFVFPNSHFLVVPKMEESMVRKAGYEGDILSYSDN
ENVWENIYARIPEHEPRNLPLICVEERLVSFERIRALQALDKQVSFTDCEGLLMEQRLQKTNEELQTLRAAAAFADRGVE
LGVAALKTGVTEMEVVAAIEYGLKQQGIREMSFQTTVLFGDHASAPHGKPGNRQLQEGEFVLFDLGVVLEGYCSDITRTV
AYGNVSEQEATIYHTVLKAQEAALAAAKPGAVIGAVDQAARHVITEAGYGAFFPHRLGHGLGIDVHESPSMHQDNQNHLK
ERMTFTVEPGIYIPDRCGVRIEDDVVITAAGCEVMTSYPKTLDPVPVRL
>Mature_369_residues
MKLERLQTLQRQMGEKQAWFAFITSKENVFYLTGYRTDPHERLIAFFVFPNSHFLVVPKMEESMVRKAGYEGDILSYSDN
ENVWENIYARIPEHEPRNLPLICVEERLVSFERIRALQALDKQVSFTDCEGLLMEQRLQKTNEELQTLRAAAAFADRGVE
LGVAALKTGVTEMEVVAAIEYGLKQQGIREMSFQTTVLFGDHASAPHGKPGNRQLQEGEFVLFDLGVVLEGYCSDITRTV
AYGNVSEQEATIYHTVLKAQEAALAAAKPGAVIGAVDQAARHVITEAGYGAFFPHRLGHGLGIDVHESPSMHQDNQNHLK
ERMTFTVEPGIYIPDRCGVRIEDDVVITAAGCEVMTSYPKTLDPVPVRL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI149589008, Length=296, Percent_Identity=28.7162162162162, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI260593665, Length=296, Percent_Identity=28.7162162162162, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI260593663, Length=247, Percent_Identity=28.7449392712551, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI40385867, Length=245, Percent_Identity=25.7142857142857, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI264681563, Length=220, Percent_Identity=30, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI93141226, Length=174, Percent_Identity=32.7586206896552, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788728, Length=319, Percent_Identity=38.5579937304075, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1789275, Length=278, Percent_Identity=29.8561151079137, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1790282, Length=310, Percent_Identity=26.7741935483871, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508215, Length=302, Percent_Identity=26.8211920529801, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71989583, Length=263, Percent_Identity=25.4752851711027, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17509539, Length=215, Percent_Identity=30.6976744186047, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321118, Length=289, Percent_Identity=26.643598615917, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320922, Length=239, Percent_Identity=26.3598326359833, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19920384, Length=260, Percent_Identity=30.3846153846154, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21357079, Length=315, Percent_Identity=28.8888888888889, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 41289; Mature: 41289

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLERLQTLQRQMGEKQAWFAFITSKENVFYLTGYRTDPHERLIAFFVFPNSHFLVVPKM
CCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCHHHEEEEEEEECCCCEEEEECH
EESMVRKAGYEGDILSYSDNENVWENIYARIPEHEPRNLPLICVEERLVSFERIRALQAL
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
DKQVSFTDCEGLLMEQRLQKTNEELQTLRAAAAFADRGVELGVAALKTGVTEMEVVAAIE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHH
YGLKQQGIREMSFQTTVLFGDHASAPHGKPGNRQLQEGEFVLFDLGVVLEGYCSDITRTV
HHHHHHCHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
AYGNVSEQEATIYHTVLKAQEAALAAAKPGAVIGAVDQAARHVITEAGYGAFFPHRLGHG
HCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCHHHHCCC
LGIDVHESPSMHQDNQNHLKERMTFTVEPGIYIPDRCGVRIEDDVVITAAGCEVMTSYPK
CCCCCCCCCCCCCCCHHHHHHHCEEEECCCEECCCCCCCEECCCEEEEECCCHHHHCCCC
TLDPVPVRL
CCCCCCCCC
>Mature Secondary Structure
MKLERLQTLQRQMGEKQAWFAFITSKENVFYLTGYRTDPHERLIAFFVFPNSHFLVVPKM
CCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEECCCCHHHEEEEEEEECCCCEEEEECH
EESMVRKAGYEGDILSYSDNENVWENIYARIPEHEPRNLPLICVEERLVSFERIRALQAL
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
DKQVSFTDCEGLLMEQRLQKTNEELQTLRAAAAFADRGVELGVAALKTGVTEMEVVAAIE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHH
YGLKQQGIREMSFQTTVLFGDHASAPHGKPGNRQLQEGEFVLFDLGVVLEGYCSDITRTV
HHHHHHCHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
AYGNVSEQEATIYHTVLKAQEAALAAAKPGAVIGAVDQAARHVITEAGYGAFFPHRLGHG
HCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCHHHHCCC
LGIDVHESPSMHQDNQNHLKERMTFTVEPGIYIPDRCGVRIEDDVVITAAGCEVMTSYPK
CCCCCCCCCCCCCCCHHHHHHHCEEEECCCEECCCCCCCEECCCEEEEECCCHHHHCCCC
TLDPVPVRL
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]