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The map label for this gene is coaA

Identifier: 56964304

GI number: 56964304

Start: 2656659

End: 2657609

Strand: Direct

Name: coaA

Synonym: ABC2539

Alternate gene names: 56964304

Gene position: 2656659-2657609 (Clockwise)

Preceding gene: 56964303

Following gene: 56964306

Centisome position: 61.73

GC content: 44.27

Gene sequence:

>951_bases
ATGACAACGGATGAATTAACAAAAAGCTTAGAGGCTTTTACCCACTTCACTCGTGCAGAATGGGCACAGCTAAATGACGG
GCATAGCGCTCCTCTCACGGAAAAAGAGCGGAAAAACCTCGAAGGGATTTATGAAACGATATCTGAGGCAGAAGTGAACG
ATGTATACATGCCTTTATCTGAATTACTTTATAAACGAATGGTCCATAATGTTAGGCTTCATGACGATTTAAATCGCTTT
TTAAAGCGGGAACGGAAGCGGGTGCCCTTTGTCATTGGCATAGCCGGGAGCGTTGCAGTCGGAAAAAGCACAACCGCAAG
GCTGATTCAAGCATTGGCCTCAAGATGGCCCGGCTCTCCGAAAGTGGAGCTTGTCACAACAGACGGCTTTCTATATCCAA
ATGAAGTGCTGGAAAAACGAGGCCTCATGAAACGGAAAGGCTTTCCAGAAAGTTACGATATCCGCAGCCTGCTTACTTTT
TTGACAGACTTAAAAGCAGGCACGCCTGTCGTAAAAGCACCTATGTATTCTCACTTGACTTATAACATTGAAAAAGATCA
TATCCAAACGTTGATAGAACCGGATGTCGTCATTGTCGAAGGCATTAATGTCCTACAAGTAAACCGAAAAGGCAAGCGCA
TGCCCCATGTGTTTGTCTCTGATTTTTTTGATTTCAGCATTTATGTCGATGCAGAGGAAAAAGACATATTATCTTGGTAT
ATCGAGCGCTTTCAACTGCTCCGTAACACAGCATTCCAAAAGCCCGAGTCGTATTTTCACCGCTACCGCGACTTAACGGA
TGAAGAAGCGGTTGCAATGGCGGAATCGATTTGGCATACCATTAATGGCGTTAATTTAGAAAAGAACATTAAGCCAACAC
GCCTTCGCGCAGACTTGATCTTAACAAAAGGCGCTCACCACCGCGTTGAGCAAGTCCAATTGCGAAAATAA

Upstream 100 bases:

>100_bases
ACATGTATACGTTCGCTCAAGTGTTCTATTCTTGATTATCCGTTTCAGCCGTGCTACGCTTCATCTATTGAAGTAAGCTC
AACCCGCAAAGGAGATCCTT

Downstream 100 bases:

>100_bases
ACGCCATATATTAACTTGCTGAAACAAAAAAACTCCGCTGCTAAAGAGCAGCGGAGTTTTTTTGGAGTGTTACCCTTTAA
ACAATTGCACGAACATTTTG

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTTDELTKSLEAFTHFTRAEWAQLNDGHSAPLTEKERKNLEGIYETISEAEVNDVYMPLSELLYKRMVHNVRLHDDLNRF
LKRERKRVPFVIGIAGSVAVGKSTTARLIQALASRWPGSPKVELVTTDGFLYPNEVLEKRGLMKRKGFPESYDIRSLLTF
LTDLKAGTPVVKAPMYSHLTYNIEKDHIQTLIEPDVVIVEGINVLQVNRKGKRMPHVFVSDFFDFSIYVDAEEKDILSWY
IERFQLLRNTAFQKPESYFHRYRDLTDEEAVAMAESIWHTINGVNLEKNIKPTRLRADLILTKGAHHRVEQVQLRK

Sequences:

>Translated_316_residues
MTTDELTKSLEAFTHFTRAEWAQLNDGHSAPLTEKERKNLEGIYETISEAEVNDVYMPLSELLYKRMVHNVRLHDDLNRF
LKRERKRVPFVIGIAGSVAVGKSTTARLIQALASRWPGSPKVELVTTDGFLYPNEVLEKRGLMKRKGFPESYDIRSLLTF
LTDLKAGTPVVKAPMYSHLTYNIEKDHIQTLIEPDVVIVEGINVLQVNRKGKRMPHVFVSDFFDFSIYVDAEEKDILSWY
IERFQLLRNTAFQKPESYFHRYRDLTDEEAVAMAESIWHTINGVNLEKNIKPTRLRADLILTKGAHHRVEQVQLRK
>Mature_315_residues
TTDELTKSLEAFTHFTRAEWAQLNDGHSAPLTEKERKNLEGIYETISEAEVNDVYMPLSELLYKRMVHNVRLHDDLNRFL
KRERKRVPFVIGIAGSVAVGKSTTARLIQALASRWPGSPKVELVTTDGFLYPNEVLEKRGLMKRKGFPESYDIRSLLTFL
TDLKAGTPVVKAPMYSHLTYNIEKDHIQTLIEPDVVIVEGINVLQVNRKGKRMPHVFVSDFFDFSIYVDAEEKDILSWYI
ERFQLLRNTAFQKPESYFHRYRDLTDEEAVAMAESIWHTINGVNLEKNIKPTRLRADLILTKGAHHRVEQVQLRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=308, Percent_Identity=53.5714285714286, Blast_Score=332, Evalue=3e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_BACSK (Q5WEY6)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_176035.1
- HSSP:   P0A6I3
- ProteinModelPortal:   Q5WEY6
- SMR:   Q5WEY6
- STRING:   Q5WEY6
- EnsemblBacteria:   EBBACT00000047371
- GeneID:   3203832
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC2539
- NMPDR:   fig|66692.3.peg.2227
- eggNOG:   COG1072
- GeneTree:   EBGT00050000002135
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- ProtClustDB:   PRK05439
- BioCyc:   BCLA66692:ABC2539-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 36586; Mature: 36455

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDELTKSLEAFTHFTRAEWAQLNDGHSAPLTEKERKNLEGIYETISEAEVNDVYMPLS
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLYKRMVHNVRLHDDLNRFLKRERKRVPFVIGIAGSVAVGKSTTARLIQALASRWPGSP
HHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCC
KVELVTTDGFLYPNEVLEKRGLMKRKGFPESYDIRSLLTFLTDLKAGTPVVKAPMYSHLT
CEEEEECCCCCCHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEECCCHHHEE
YNIEKDHIQTLIEPDVVIVEGINVLQVNRKGKRMPHVFVSDFFDFSIYVDAEEKDILSWY
ECCCHHHHHHHHCCCEEEEECCCEEEECCCCCCCCHHHHHHHCCEEEEECCCHHHHHHHH
IERFQLLRNTAFQKPESYFHRYRDLTDEEAVAMAESIWHTINGVNLEKNIKPTRLRADLI
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHE
LTKGAHHRVEQVQLRK
EECCCHHHHHHHHCCC
>Mature Secondary Structure 
TTDELTKSLEAFTHFTRAEWAQLNDGHSAPLTEKERKNLEGIYETISEAEVNDVYMPLS
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLYKRMVHNVRLHDDLNRFLKRERKRVPFVIGIAGSVAVGKSTTARLIQALASRWPGSP
HHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCC
KVELVTTDGFLYPNEVLEKRGLMKRKGFPESYDIRSLLTFLTDLKAGTPVVKAPMYSHLT
CEEEEECCCCCCHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEECCCHHHEE
YNIEKDHIQTLIEPDVVIVEGINVLQVNRKGKRMPHVFVSDFFDFSIYVDAEEKDILSWY
ECCCHHHHHHHHCCCEEEEECCCEEEECCCCCCCCHHHHHHHCCEEEEECCCHHHHHHHH
IERFQLLRNTAFQKPESYFHRYRDLTDEEAVAMAESIWHTINGVNLEKNIKPTRLRADLI
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHE
LTKGAHHRVEQVQLRK
EECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA