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The map label for this gene is namA [H]

Identifier: 56964206

GI number: 56964206

Start: 2569167

End: 2570189

Strand: Direct

Name: namA [H]

Synonym: ABC2441

Alternate gene names: 56964206

Gene position: 2569167-2570189 (Clockwise)

Preceding gene: 56964203

Following gene: 56964207

Centisome position: 59.69

GC content: 52.3

Gene sequence:

>1023_bases
TTGCCAAACTTAATGGACAGCTTTCAACTGAAAGAGCTTACGTTGAAAAACCGTGTCGTCATGTCGCCTATGTGCCAATA
TTCGGCTACAGGCAAAGACGGAATGCCGACTGACTGGCATTTGCACCATTACACGAGCAGAGCAATTGGCGGCGTTGGCC
TAATTATTGTGGAAATGACCAATGTCGAGCCGAATGGGCGGATTAGCGATTACTGCCTTGGCCTTTGGTCAGACGCCCAT
CGCGATGCGTTTAAGCCGATTGTCGATGCAGCTCACCAATATGGTGCCAAAATCGCCATTCAAATCGCCCATGCTGGCAG
AAAAGCGGAAGACGCACCTGAACCCGTTGCGCCATCCGCCCAGGCATTTGACGAAACATACAAAACCCCTCGAGCGCTGT
CAGAGAACGAAATCGCTGAGATGGTGCAAACGTTTAAGGCAGCAGCCCGCCGAGCAGTAGAAGCGGGATTTGACGCGATT
GAACTCCATGGCGCCCATGGCTATTTAATCCATCAATTCCTTTCACCATATACGAATACACGAACAGACCGTTACGGTAA
AGACCGCACGCTCTTCGCCAAAGAAGTCATTCGCGCGGTCAAAAGCGTCATCCCCGACAGCATGCCTTTATTGATGCGTA
TTTCAGCAACCGAATATGTCGATGGCGGCTACGATATAGAAGAAGCCATCCGCTTCTCACAGATTTTAAAAGACGAAGGA
GTCGACGTATTCGACGTCAGCTCTGGCGGCGAAGGGCCAATCGGCTCTAGAGGGCTGCCTGGAAGCCACGCAGGTTACCA
AACGCCGCTGGCAAAACAGATCAAACAGGCACTATCTGTCCCTGTCATCGCCGTCGGCCGCCTCGAAAACCCTGTTTTAG
CCAATGCCGTAATCGGCAATGAAGAAGCCGATCTCGTCGCCGTTGGCCGCGGCCTGTTAGCCAACCCATACTGGGCCCTT
GGCGCTGCGTCTGAATTACAGCTTCCTGTTGAGGCTCCTACTCAGTATAAGGCTGGGTTTTAG

Upstream 100 bases:

>100_bases
TAACCGTACTGAAACGCCCCCTTGCAAGCATTTTGCTTGAATTGCGGGCAACATCTCTTTACGATAAGCCTGAACAAACG
AAAAATGGGAGTGGTTCAAA

Downstream 100 bases:

>100_bases
GTAGGAAAGAGGCATGGTTAACGCCCCTCAAAGTCGTTTCGGGGGCGTTTTTATAATTAAATGTAGTTTGGCCTATGCCA
ATCTCGCAAACCGATCAACA

Product: NADH-dependent flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MPNLMDSFQLKELTLKNRVVMSPMCQYSATGKDGMPTDWHLHHYTSRAIGGVGLIIVEMTNVEPNGRISDYCLGLWSDAH
RDAFKPIVDAAHQYGAKIAIQIAHAGRKAEDAPEPVAPSAQAFDETYKTPRALSENEIAEMVQTFKAAARRAVEAGFDAI
ELHGAHGYLIHQFLSPYTNTRTDRYGKDRTLFAKEVIRAVKSVIPDSMPLLMRISATEYVDGGYDIEEAIRFSQILKDEG
VDVFDVSSGGEGPIGSRGLPGSHAGYQTPLAKQIKQALSVPVIAVGRLENPVLANAVIGNEEADLVAVGRGLLANPYWAL
GAASELQLPVEAPTQYKAGF

Sequences:

>Translated_340_residues
MPNLMDSFQLKELTLKNRVVMSPMCQYSATGKDGMPTDWHLHHYTSRAIGGVGLIIVEMTNVEPNGRISDYCLGLWSDAH
RDAFKPIVDAAHQYGAKIAIQIAHAGRKAEDAPEPVAPSAQAFDETYKTPRALSENEIAEMVQTFKAAARRAVEAGFDAI
ELHGAHGYLIHQFLSPYTNTRTDRYGKDRTLFAKEVIRAVKSVIPDSMPLLMRISATEYVDGGYDIEEAIRFSQILKDEG
VDVFDVSSGGEGPIGSRGLPGSHAGYQTPLAKQIKQALSVPVIAVGRLENPVLANAVIGNEEADLVAVGRGLLANPYWAL
GAASELQLPVEAPTQYKAGF
>Mature_339_residues
PNLMDSFQLKELTLKNRVVMSPMCQYSATGKDGMPTDWHLHHYTSRAIGGVGLIIVEMTNVEPNGRISDYCLGLWSDAHR
DAFKPIVDAAHQYGAKIAIQIAHAGRKAEDAPEPVAPSAQAFDETYKTPRALSENEIAEMVQTFKAAARRAVEAGFDAIE
LHGAHGYLIHQFLSPYTNTRTDRYGKDRTLFAKEVIRAVKSVIPDSMPLLMRISATEYVDGGYDIEEAIRFSQILKDEGV
DVFDVSSGGEGPIGSRGLPGSHAGYQTPLAKQIKQALSVPVIAVGRLENPVLANAVIGNEEADLVAVGRGLLANPYWALG
AASELQLPVEAPTQYKAGF

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=326, Percent_Identity=31.2883435582822, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1787939, Length=339, Percent_Identity=30.0884955752212, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17559804, Length=337, Percent_Identity=29.9703264094956, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17564188, Length=315, Percent_Identity=30.4761904761905, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI72001454, Length=333, Percent_Identity=29.4294294294294, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17559802, Length=260, Percent_Identity=30.3846153846154, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17540738, Length=261, Percent_Identity=29.8850574712644, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17565138, Length=240, Percent_Identity=30.4166666666667, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17566914, Length=251, Percent_Identity=28.2868525896414, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6321973, Length=230, Percent_Identity=28.695652173913, Blast_Score=96, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6325086, Length=230, Percent_Identity=27.8260869565217, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 36904; Mature: 36773

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNLMDSFQLKELTLKNRVVMSPMCQYSATGKDGMPTDWHLHHYTSRAIGGVGLIIVEMT
CCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEEEE
NVEPNGRISDYCLGLWSDAHRDAFKPIVDAAHQYGAKIAIQIAHAGRKAEDAPEPVAPSA
CCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCH
QAFDETYKTPRALSENEIAEMVQTFKAAARRAVEAGFDAIELHGAHGYLIHQFLSPYTNT
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCC
RTDRYGKDRTLFAKEVIRAVKSVIPDSMPLLMRISATEYVDGGYDIEEAIRFSQILKDEG
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHCCCCCCHHHHHHHHHHHHHCC
VDVFDVSSGGEGPIGSRGLPGSHAGYQTPLAKQIKQALSVPVIAVGRLENPVLANAVIGN
CCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCEEEHEEECC
EEADLVAVGRGLLANPYWALGAASELQLPVEAPTQYKAGF
CCCCEEEECCCHHCCCCHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PNLMDSFQLKELTLKNRVVMSPMCQYSATGKDGMPTDWHLHHYTSRAIGGVGLIIVEMT
CCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEEEE
NVEPNGRISDYCLGLWSDAHRDAFKPIVDAAHQYGAKIAIQIAHAGRKAEDAPEPVAPSA
CCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCH
QAFDETYKTPRALSENEIAEMVQTFKAAARRAVEAGFDAIELHGAHGYLIHQFLSPYTNT
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCC
RTDRYGKDRTLFAKEVIRAVKSVIPDSMPLLMRISATEYVDGGYDIEEAIRFSQILKDEG
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHCCCCCCHHHHHHHHHHHHHCC
VDVFDVSSGGEGPIGSRGLPGSHAGYQTPLAKQIKQALSVPVIAVGRLENPVLANAVIGN
CCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCEEEHEEECC
EEADLVAVGRGLLANPYWALGAASELQLPVEAPTQYKAGF
CCCCEEEECCCHHCCCCHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]