Click here to switch to the map view.

The map label for this gene is speA [H]

Identifier: 56964172

GI number: 56964172

Start: 2532765

End: 2534243

Strand: Direct

Name: speA [H]

Synonym: ABC2407

Alternate gene names: 56964172

Gene position: 2532765-2534243 (Clockwise)

Preceding gene: 56964170

Following gene: 56964175

Centisome position: 58.85

GC content: 45.91

Gene sequence:

>1479_bases
ATGGGACACGACCAAGAACAAACCCCGTTATTTACGGGTTTAACCGAATATGCCAAAAAAGAGCCAATCCCTTTTCATAT
ACCAGGCCATAAACGAGGAGCAGGCATGGACGCCGATTTTCGCACTTTTATAGGCGAAGAAGCGCTGTCCATTGACTTGA
TTAACATTGCCCCTCTCGATGACTTACACCATCCTCATGGCATTATTGATCAATCTCAGCAATTGGCAGCCAAAGCATTT
GGAGCTGATTATACATTTTTCTCTGTACAAGGCACAAGCGGGGCCATCATGACTATGATTATGAGCGTATGTGGGCCAGG
CGATAAAATTATTGTCCCTCGCAACGTTCATAAATCCATTATGTCAGCGATTATTTTTTGCGGGGCATTGCCTGTGTTTA
TCCATCCAGAACTCGACTTTGAACATGGGATTGCTCACGGGGTAGCGACAGAGTCAGTTGCCAAAGCGATACGCGCTCAT
CCTGACGCAAAAGCCGTCCTTGTGATCAACCCTACTTACTACGGATTTACTTGCGATTTAAAGGCGATTGTCGAATTAGC
CCATCAAGCGGGCATTCCTGTACTTGTTGATGAAGCACACGGCGTACACATCCATTTTAATGAGCGTCTGCCGGTAAGCG
CAATGCAAGCAGGAGCAGACATGGCAGCGACGAGCGTGCATAAATTAGGAGGTTCGCTGACACAAAGTTCCATATTAAAT
ATTCGTGCCGGGCTTGTATCCGTTGAACATACAACGGCCGTTATGAGCATGCTGACAACCACATCGACTTCTTATTTGCT
CCTTGCCTCCCTGGATGCGGCGAGAAAACATCTGGCTACAAAAGGAGCCCAACTCCTCGATGAGACCATCGACTTGTCGA
TTTGGATGCGCCATGCAATTAATGAGATTGACGGACTATACTGCCTTGGCAGCGAAAAACTCCATGGATCCGCTGTATTT
TCCCATGACCCCACGAAGCTATTAATTTCTTTAAAAGGCTTAAACATTTCTGGTTTTGCCGCAGAAGTTTGGCTACGGGA
CCATTACAATATTGAAGTTGAACTTTCCGACTTGTACAATATTCTTTGCATCATTACCATTGGCGATACAGAGGAAAAGC
TTGCTTTGTTGCTGAGAGCATTAACGCAACTGGCGCTGGAATTTTCTTCAACGGCTAATCGTTGTGCGTCTTTACCCGTC
CATGTCGCCAATATTCCAACGCTTGCCCTTTCGCCGCGTGAAGCCTTTTATGCGCAAACAGAAACAGTGCCATTTGATGA
ATCTGTTGGCCGGATTATTGCCGAGTTTATTATGGTCTATCCTCCAGGCATCCCTATTCTTAGCCCAGGGGAATTGATCA
GTGAAGAAAACCTCGCTTATGTAAAAGAAAACTTGAAAGCTGGCCTTCCTGTCCAAGGTCCAGAAGACGCTACACTTTCC
AACTTGAAAGTGATTAAAGAGCAACGCGCCATTCGATAA

Upstream 100 bases:

>100_bases
CCTTTCCTTTTTTCTATCCGTAGGCAAATGCGCTCCATTTTGCTATACTCTTCTTGTTTGCTTTGTATAAGCTTCAATTT
CCTTAAGTGAGGTGGCCTTC

Downstream 100 bases:

>100_bases
AATACGCACGTGCGTGTTGCTAGCGTTAAGCGAGAGGAGAAAAGCACAAAAAGCGTGCTGAAAAACGGATAGTTTCAGCA
CGCTTTTTTTGTTCTATTTA

Product: arginine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MGHDQEQTPLFTGLTEYAKKEPIPFHIPGHKRGAGMDADFRTFIGEEALSIDLINIAPLDDLHHPHGIIDQSQQLAAKAF
GADYTFFSVQGTSGAIMTMIMSVCGPGDKIIVPRNVHKSIMSAIIFCGALPVFIHPELDFEHGIAHGVATESVAKAIRAH
PDAKAVLVINPTYYGFTCDLKAIVELAHQAGIPVLVDEAHGVHIHFNERLPVSAMQAGADMAATSVHKLGGSLTQSSILN
IRAGLVSVEHTTAVMSMLTTTSTSYLLLASLDAARKHLATKGAQLLDETIDLSIWMRHAINEIDGLYCLGSEKLHGSAVF
SHDPTKLLISLKGLNISGFAAEVWLRDHYNIEVELSDLYNILCIITIGDTEEKLALLLRALTQLALEFSSTANRCASLPV
HVANIPTLALSPREAFYAQTETVPFDESVGRIIAEFIMVYPPGIPILSPGELISEENLAYVKENLKAGLPVQGPEDATLS
NLKVIKEQRAIR

Sequences:

>Translated_492_residues
MGHDQEQTPLFTGLTEYAKKEPIPFHIPGHKRGAGMDADFRTFIGEEALSIDLINIAPLDDLHHPHGIIDQSQQLAAKAF
GADYTFFSVQGTSGAIMTMIMSVCGPGDKIIVPRNVHKSIMSAIIFCGALPVFIHPELDFEHGIAHGVATESVAKAIRAH
PDAKAVLVINPTYYGFTCDLKAIVELAHQAGIPVLVDEAHGVHIHFNERLPVSAMQAGADMAATSVHKLGGSLTQSSILN
IRAGLVSVEHTTAVMSMLTTTSTSYLLLASLDAARKHLATKGAQLLDETIDLSIWMRHAINEIDGLYCLGSEKLHGSAVF
SHDPTKLLISLKGLNISGFAAEVWLRDHYNIEVELSDLYNILCIITIGDTEEKLALLLRALTQLALEFSSTANRCASLPV
HVANIPTLALSPREAFYAQTETVPFDESVGRIIAEFIMVYPPGIPILSPGELISEENLAYVKENLKAGLPVQGPEDATLS
NLKVIKEQRAIR
>Mature_491_residues
GHDQEQTPLFTGLTEYAKKEPIPFHIPGHKRGAGMDADFRTFIGEEALSIDLINIAPLDDLHHPHGIIDQSQQLAAKAFG
ADYTFFSVQGTSGAIMTMIMSVCGPGDKIIVPRNVHKSIMSAIIFCGALPVFIHPELDFEHGIAHGVATESVAKAIRAHP
DAKAVLVINPTYYGFTCDLKAIVELAHQAGIPVLVDEAHGVHIHFNERLPVSAMQAGADMAATSVHKLGGSLTQSSILNI
RAGLVSVEHTTAVMSMLTTTSTSYLLLASLDAARKHLATKGAQLLDETIDLSIWMRHAINEIDGLYCLGSEKLHGSAVFS
HDPTKLLISLKGLNISGFAAEVWLRDHYNIEVELSDLYNILCIITIGDTEEKLALLLRALTQLALEFSSTANRCASLPVH
VANIPTLALSPREAFYAQTETVPFDESVGRIIAEFIMVYPPGIPILSPGELISEENLAYVKENLKAGLPVQGPEDATLSN
LKVIKEQRAIR

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=546, Percent_Identity=25.2747252747253, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786384, Length=547, Percent_Identity=24.6800731261426, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI221142684, Length=579, Percent_Identity=24.006908462867, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI87082193, Length=571, Percent_Identity=24.8686514886165, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786909, Length=585, Percent_Identity=23.5897435897436, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 53263; Mature: 53132

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHDQEQTPLFTGLTEYAKKEPIPFHIPGHKRGAGMDADFRTFIGEEALSIDLINIAPLD
CCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHCCCCEEEEEEEECCCH
DLHHPHGIIDQSQQLAAKAFGADYTFFSVQGTSGAIMTMIMSVCGPGDKIIVPRNVHKSI
HCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEECCHHHHHH
MSAIIFCGALPVFIHPELDFEHGIAHGVATESVAKAIRAHPDAKAVLVINPTYYGFTCDL
HHHHHHHCCCCEEEECCCCHHHCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECH
KAIVELAHQAGIPVLVDEAHGVHIHFNERLPVSAMQAGADMAATSVHKLGGSLTQSSILN
HHHHHHHHHCCCCEEEECCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHHH
IRAGLVSVEHTTAVMSMLTTTSTSYLLLASLDAARKHLATKGAQLLDETIDLSIWMRHAI
HHHHEEEHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEIDGLYCLGSEKLHGSAVFSHDPTKLLISLKGLNISGFAAEVWLRDHYNIEVELSDLYN
HHCCCEEEECCCCCCCCEEECCCCCEEEEEEECCCCCCEEEEEEEECCCEEEEEHHHCEE
ILCIITIGDTEEKLALLLRALTQLALEFSSTANRCASLPVHVANIPTLALSPREAFYAQT
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCHHHHHCCC
ETVPFDESVGRIIAEFIMVYPPGIPILSPGELISEENLAYVKENLKAGLPVQGPEDATLS
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHH
NLKVIKEQRAIR
HHHHHHHHHCCC
>Mature Secondary Structure 
GHDQEQTPLFTGLTEYAKKEPIPFHIPGHKRGAGMDADFRTFIGEEALSIDLINIAPLD
CCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHCCCCEEEEEEEECCCH
DLHHPHGIIDQSQQLAAKAFGADYTFFSVQGTSGAIMTMIMSVCGPGDKIIVPRNVHKSI
HCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEECCHHHHHH
MSAIIFCGALPVFIHPELDFEHGIAHGVATESVAKAIRAHPDAKAVLVINPTYYGFTCDL
HHHHHHHCCCCEEEECCCCHHHCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECH
KAIVELAHQAGIPVLVDEAHGVHIHFNERLPVSAMQAGADMAATSVHKLGGSLTQSSILN
HHHHHHHHHCCCCEEEECCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHHH
IRAGLVSVEHTTAVMSMLTTTSTSYLLLASLDAARKHLATKGAQLLDETIDLSIWMRHAI
HHHHEEEHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEIDGLYCLGSEKLHGSAVFSHDPTKLLISLKGLNISGFAAEVWLRDHYNIEVELSDLYN
HHCCCEEEECCCCCCCCEEECCCCCEEEEEEECCCCCCEEEEEEEECCCEEEEEHHHCEE
ILCIITIGDTEEKLALLLRALTQLALEFSSTANRCASLPVHVANIPTLALSPREAFYAQT
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCHHHHHCCC
ETVPFDESVGRIIAEFIMVYPPGIPILSPGELISEENLAYVKENLKAGLPVQGPEDATLS
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHH
NLKVIKEQRAIR
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]