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The map label for this gene is yagI [H]

Identifier: 56963937

GI number: 56963937

Start: 2291914

End: 2292660

Strand: Direct

Name: yagI [H]

Synonym: ABC2172

Alternate gene names: 56963937

Gene position: 2291914-2292660 (Clockwise)

Preceding gene: 56963936

Following gene: 56963943

Centisome position: 53.25

GC content: 47.66

Gene sequence:

>747_bases
ATGGAGCAAAAATATCATGTGCCTGCCTTAGATCGAGCCAACGCTGTATTAACGGTTTTAAGAGACGAACCATACAGATG
GAAGTTATCCGATTTGTCGAAAATGATCGGGATTAGCAAAAGCACGCTCCATTCGCTGTTAGCAACAATGGAGCGCTTGC
AATGGGTAAGCCGTGATCGCAATGAAACATATGCGATTGGGAGCGCTATAGGACGTTTTGGGAGCGCTTTTTTCCAGCAG
TTCGATCTGAGTGAAGATTTTCGGCGCTTGGCCGAGCCAGTGATGCGCAATCTTCAAGAATCGATCCAACTAGCAGTGCT
TGAAGGCAGCGACGTCCAATATTTAGCTAAAGTAGAAGCCCCCAGTCCTGTCCAGATGGTTTCAGGTCCAGGAGTTCGCT
TCCCTGCGCATGCAACGGGTCTAGGAAAAGCTTTGATGGCCGACATGAATGAACAACAAATATGCAACTTATATCCGGAA
GAATCACTTCCTAAAATTACCGTTCATACGATCGGCTCCAGGGAAGCTTTGATCCACGAGCTTAAGAATGTACGGAAAGC
TGGATATGCAATGGATATTCAGGAAGGCGTCATGGGCTTTTGCTGTACAGCCGCACCGATTCGTAAAGCAAACGGAGAAA
TCGCCGCTGCGATCAGTTGTTCCATGCCGATTCACCATTGGGAAGGGAAGAAAGAGCGTGCCTTGGAAGAAATTGTCCAA
CTTGCCCAGCGCCTTTCTCACCTTTAA

Upstream 100 bases:

>100_bases
AAAGCCTTGCTATTCGTTTGACGGCCCATCATCGAAAATGGTACGATTTTAACTGTTCATAATAACGAACAATATACTGT
TTTAGGGCGTGAATTTATAG

Downstream 100 bases:

>100_bases
TCATCGCATCATCCCCTCCACTCCTGAGAGATGAAAAACAGCCTTGTTCCGACATGTTCAAGTTTCGGAGCAAGGCTACA
TGGTTTTCTAGTTGTTGCAT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MEQKYHVPALDRANAVLTVLRDEPYRWKLSDLSKMIGISKSTLHSLLATMERLQWVSRDRNETYAIGSAIGRFGSAFFQQ
FDLSEDFRRLAEPVMRNLQESIQLAVLEGSDVQYLAKVEAPSPVQMVSGPGVRFPAHATGLGKALMADMNEQQICNLYPE
ESLPKITVHTIGSREALIHELKNVRKAGYAMDIQEGVMGFCCTAAPIRKANGEIAAAISCSMPIHHWEGKKERALEEIVQ
LAQRLSHL

Sequences:

>Translated_248_residues
MEQKYHVPALDRANAVLTVLRDEPYRWKLSDLSKMIGISKSTLHSLLATMERLQWVSRDRNETYAIGSAIGRFGSAFFQQ
FDLSEDFRRLAEPVMRNLQESIQLAVLEGSDVQYLAKVEAPSPVQMVSGPGVRFPAHATGLGKALMADMNEQQICNLYPE
ESLPKITVHTIGSREALIHELKNVRKAGYAMDIQEGVMGFCCTAAPIRKANGEIAAAISCSMPIHHWEGKKERALEEIVQ
LAQRLSHL
>Mature_248_residues
MEQKYHVPALDRANAVLTVLRDEPYRWKLSDLSKMIGISKSTLHSLLATMERLQWVSRDRNETYAIGSAIGRFGSAFFQQ
FDLSEDFRRLAEPVMRNLQESIQLAVLEGSDVQYLAKVEAPSPVQMVSGPGVRFPAHATGLGKALMADMNEQQICNLYPE
ESLPKITVHTIGSREALIHELKNVRKAGYAMDIQEGVMGFCCTAAPIRKANGEIAAAISCSMPIHHWEGKKERALEEIVQ
LAQRLSHL

Specific function: Unknown

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=216, Percent_Identity=30.0925925925926, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082359, Length=226, Percent_Identity=32.7433628318584, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786715, Length=220, Percent_Identity=29.5454545454545, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1788131, Length=218, Percent_Identity=29.8165137614679, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788581, Length=228, Percent_Identity=27.6315789473684, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1790752, Length=210, Percent_Identity=25.2380952380952, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789999, Length=250, Percent_Identity=24, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27689; Mature: 27689

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQKYHVPALDRANAVLTVLRDEPYRWKLSDLSKMIGISKSTLHSLLATMERLQWVSRDR
CCCCCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
NETYAIGSAIGRFGSAFFQQFDLSEDFRRLAEPVMRNLQESIQLAVLEGSDVQYLAKVEA
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCC
PSPVQMVSGPGVRFPAHATGLGKALMADMNEQQICNLYPEESLPKITVHTIGSREALIHE
CCCHHECCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEEEEECCCHHHHHHH
LKNVRKAGYAMDIQEGVMGFCCTAAPIRKANGEIAAAISCSMPIHHWEGKKERALEEIVQ
HHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCCEEEEEEECCCCHHCCCHHHHHHHHHHH
LAQRLSHL
HHHHHHCC
>Mature Secondary Structure
MEQKYHVPALDRANAVLTVLRDEPYRWKLSDLSKMIGISKSTLHSLLATMERLQWVSRDR
CCCCCCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
NETYAIGSAIGRFGSAFFQQFDLSEDFRRLAEPVMRNLQESIQLAVLEGSDVQYLAKVEA
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEECCC
PSPVQMVSGPGVRFPAHATGLGKALMADMNEQQICNLYPEESLPKITVHTIGSREALIHE
CCCHHECCCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEEEEECCCHHHHHHH
LKNVRKAGYAMDIQEGVMGFCCTAAPIRKANGEIAAAISCSMPIHHWEGKKERALEEIVQ
HHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCCEEEEEEECCCCHHCCCHHHHHHHHHHH
LAQRLSHL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]