Click here to switch to the map view.

The map label for this gene is dapA [H]

Identifier: 56963795

GI number: 56963795

Start: 2146301

End: 2147206

Strand: Direct

Name: dapA [H]

Synonym: ABC2030

Alternate gene names: 56963795

Gene position: 2146301-2147206 (Clockwise)

Preceding gene: 56963794

Following gene: 56963801

Centisome position: 49.87

GC content: 50.0

Gene sequence:

>906_bases
ATGGATTTTGGCTACCTGATGACGGCAATGGTCACACCTTTTACAAACGAAAATGCTTTAGATGTGAATGGCATACGTAC
GCTCATACACCATTTAGCAAATAATGGGACGGATACGGTCGTTATCCATGGCACTACAGGCGAAGCCCCAACACTAACAC
TTGAAGAAAAACAAACGCTCCTTTCAGTCGCGGTGGAAGAAGCAGCCAATGCAAACATAAAGGTGATTGCCGGCATCGGC
GCAAACAGTACACAACAGGCGGTACAAATGGCACAGTTAGCTGAGCAAACAGGAGCGGATGGGCTGATGGTCGTTGTGCC
TTATTACAACAAGCCATCCCAAGAAGGGATTTACCAACATATTGCCCAAGTGGCTCAATCCACTCCTTTACCTGTCCTGC
TTTATAACGTACCAGGCCGTACAGGTGCTGACATGAGTGCGGAAACAGCATTGAGGCTGGCTGAGATCGACCAAGTATTT
GCGATTAAAGAAGCGAGCGGAAATATCGATAAAGTCACGGAGATTCTGCGTCTCGCCCCGGAAGGCTTTTCGGTATACAG
CGGCGATGATTCGTTGACGCTGCCAATGATGGCAGTTGGCGCTAAAGGCGTTGTCTCCGTTGCCTCCCATATTGTTGGCC
GTGAAATGAAGCAAATGATCGATGCTTTTGCAAGTGGCGAGCTGCAGCTTGCTGCCTCGATCCACCATAAGCTTTTCCCT
GTCATGAAAGCGATGTTTATGGCACCGAGCCCTGCTCCTGTCAAAGAAGCGCTTGCTCGTTATCGGTTACCAGGCGGCGG
GGTGCGTTTGCCGCTAATTGGCCTTAATGAAGCGGAAAACATGGAGCTCGCAGCGGTGCTTGAACCGTTTTTGCCAATAG
CGAGTCGTTCGGTTGCCTCTTCATGA

Upstream 100 bases:

>100_bases
CTCAAACTTGGAAAACGACCCGTTTGCCTAGTGCAACAATGAGCCTCTGTCATTGTTGTTTTTTTGTGCCTCTACTCGCC
ACCTATTTAGGAGGATTCCC

Downstream 100 bases:

>100_bases
AAAAAGTTCCCTCATGTACGTATGAGGGAACTTTTTTATATCGTTAACCTTTTTTAAAAACGGTATTCCTTCCTAACTTC
TTGAAGCAGCTGCAAACTTT

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MDFGYLMTAMVTPFTNENALDVNGIRTLIHHLANNGTDTVVIHGTTGEAPTLTLEEKQTLLSVAVEEAANANIKVIAGIG
ANSTQQAVQMAQLAEQTGADGLMVVVPYYNKPSQEGIYQHIAQVAQSTPLPVLLYNVPGRTGADMSAETALRLAEIDQVF
AIKEASGNIDKVTEILRLAPEGFSVYSGDDSLTLPMMAVGAKGVVSVASHIVGREMKQMIDAFASGELQLAASIHHKLFP
VMKAMFMAPSPAPVKEALARYRLPGGGVRLPLIGLNEAENMELAAVLEPFLPIASRSVASS

Sequences:

>Translated_301_residues
MDFGYLMTAMVTPFTNENALDVNGIRTLIHHLANNGTDTVVIHGTTGEAPTLTLEEKQTLLSVAVEEAANANIKVIAGIG
ANSTQQAVQMAQLAEQTGADGLMVVVPYYNKPSQEGIYQHIAQVAQSTPLPVLLYNVPGRTGADMSAETALRLAEIDQVF
AIKEASGNIDKVTEILRLAPEGFSVYSGDDSLTLPMMAVGAKGVVSVASHIVGREMKQMIDAFASGELQLAASIHHKLFP
VMKAMFMAPSPAPVKEALARYRLPGGGVRLPLIGLNEAENMELAAVLEPFLPIASRSVASS
>Mature_301_residues
MDFGYLMTAMVTPFTNENALDVNGIRTLIHHLANNGTDTVVIHGTTGEAPTLTLEEKQTLLSVAVEEAANANIKVIAGIG
ANSTQQAVQMAQLAEQTGADGLMVVVPYYNKPSQEGIYQHIAQVAQSTPLPVLLYNVPGRTGADMSAETALRLAEIDQVF
AIKEASGNIDKVTEILRLAPEGFSVYSGDDSLTLPMMAVGAKGVVSVASHIVGREMKQMIDAFASGELQLAASIHHKLFP
VMKAMFMAPSPAPVKEALARYRLPGGGVRLPLIGLNEAENMELAAVLEPFLPIASRSVASS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=289, Percent_Identity=28.3737024221453, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI13540533, Length=232, Percent_Identity=27.1551724137931, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1788823, Length=283, Percent_Identity=37.4558303886926, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI87082415, Length=241, Percent_Identity=29.4605809128631, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789620, Length=238, Percent_Identity=29.4117647058824, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786463, Length=266, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31893; Mature: 31893

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFGYLMTAMVTPFTNENALDVNGIRTLIHHLANNGTDTVVIHGTTGEAPTLTLEEKQTL
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHHHHH
LSVAVEEAANANIKVIAGIGANSTQQAVQMAQLAEQTGADGLMVVVPYYNKPSQEGIYQH
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
IAQVAQSTPLPVLLYNVPGRTGADMSAETALRLAEIDQVFAIKEASGNIDKVTEILRLAP
HHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCC
EGFSVYSGDDSLTLPMMAVGAKGVVSVASHIVGREMKQMIDAFASGELQLAASIHHKLFP
CCCEEECCCCCEECHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
VMKAMFMAPSPAPVKEALARYRLPGGGVRLPLIGLNEAENMELAAVLEPFLPIASRSVAS
HHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
S
C
>Mature Secondary Structure
MDFGYLMTAMVTPFTNENALDVNGIRTLIHHLANNGTDTVVIHGTTGEAPTLTLEEKQTL
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHHHHH
LSVAVEEAANANIKVIAGIGANSTQQAVQMAQLAEQTGADGLMVVVPYYNKPSQEGIYQH
HHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
IAQVAQSTPLPVLLYNVPGRTGADMSAETALRLAEIDQVFAIKEASGNIDKVTEILRLAP
HHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCC
EGFSVYSGDDSLTLPMMAVGAKGVVSVASHIVGREMKQMIDAFASGELQLAASIHHKLFP
CCCEEECCCCCEECHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
VMKAMFMAPSPAPVKEALARYRLPGGGVRLPLIGLNEAENMELAAVLEPFLPIASRSVAS
HHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA