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The map label for this gene is dapB

Identifier: 56963681

GI number: 56963681

Start: 2031471

End: 2032265

Strand: Direct

Name: dapB

Synonym: ABC1916

Alternate gene names: 56963681

Gene position: 2031471-2032265 (Clockwise)

Preceding gene: 56963680

Following gene: 56963682

Centisome position: 47.2

GC content: 47.55

Gene sequence:

>795_bases
ATGACACGTATTGTAATTGCAGGGCCACGTGGCAACATGGGCCAAGAAGCAGTCAAACTTTGTCTGCGAGAAGAATCATT
TGAACTGGTTGCTGTAGTTGATTCAAAAAATGACGGCAAGCAATTAAAAGGTTTGCAAGAATTCCAACAAGGCGATGTGC
CAGTATATACCGATATGGCACGCTGTTTTGCGGAGCATGAACCAGATGTATTAATTGATTTGACGGCACCTGCCTTTGGT
AGAAAACATATGGAAGTGGCGTTTGAGCATGGCGTTCGTCCGGTTGTGGGAACGACAGGGTTTAGTGATGAAGATATTCG
CGATTTAACGAAACTGGCTGAAGCAAAAGAGCTGGGCGCCATCATCGCTCCTAACTTTGCTATCGGCGCGATTTTAATGA
TGAAATTCGCGCAAACGGCAGCACGGTACATGAATGACGTTGAAATTATTGAACAGCACCATGACCGCAAGCTTGATGCG
CCATCGGGTACAGCGGTAAAAACGGCACAGCTCATTGCAGAGGTGCGGGCTCCGAAAAAGCAAGGGCATGAGCAGGAAAG
AGAAGAGATGGCAGGCGCAAGAGGAGCTGACTTCGATGGCATGAAAATCCACTCTGTCCGTTTACCTGGGCGAGTGGCCC
ATCAAGAAGTGCTGTTTGGCGGAGTGGGGCAAACGTTATCGATACGCCACGATTCGCTAAACCGTGAAAGTTTTATGCCT
GGCGTAAAGCTTGCCGTTGAACAAGTGGTCAAGCTCTCGACGCTAGTATATGGTCTTGAAAATTTAATCGATTAA

Upstream 100 bases:

>100_bases
TTCAAATCGATTTAAGCGAAGCGCATGATCTTGTCATGCATAAATTCCAAACAAGAGACAAAGACCGCTGGACGAAAAAA
GAAAAAGGAGAACAGAATCA

Downstream 100 bases:

>100_bases
GGGGAGAACGACATGAAAATCGCTTTAATTGCCCACGACAAGAAAAAACAAGAATTGGTTGATTTTTGTGTTGCTTATGA
GCCCATTTTAAAAGAGCATG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTRIVIAGPRGNMGQEAVKLCLREESFELVAVVDSKNDGKQLKGLQEFQQGDVPVYTDMARCFAEHEPDVLIDLTAPAFG
RKHMEVAFEHGVRPVVGTTGFSDEDIRDLTKLAEAKELGAIIAPNFAIGAILMMKFAQTAARYMNDVEIIEQHHDRKLDA
PSGTAVKTAQLIAEVRAPKKQGHEQEREEMAGARGADFDGMKIHSVRLPGRVAHQEVLFGGVGQTLSIRHDSLNRESFMP
GVKLAVEQVVKLSTLVYGLENLID

Sequences:

>Translated_264_residues
MTRIVIAGPRGNMGQEAVKLCLREESFELVAVVDSKNDGKQLKGLQEFQQGDVPVYTDMARCFAEHEPDVLIDLTAPAFG
RKHMEVAFEHGVRPVVGTTGFSDEDIRDLTKLAEAKELGAIIAPNFAIGAILMMKFAQTAARYMNDVEIIEQHHDRKLDA
PSGTAVKTAQLIAEVRAPKKQGHEQEREEMAGARGADFDGMKIHSVRLPGRVAHQEVLFGGVGQTLSIRHDSLNRESFMP
GVKLAVEQVVKLSTLVYGLENLID
>Mature_263_residues
TRIVIAGPRGNMGQEAVKLCLREESFELVAVVDSKNDGKQLKGLQEFQQGDVPVYTDMARCFAEHEPDVLIDLTAPAFGR
KHMEVAFEHGVRPVVGTTGFSDEDIRDLTKLAEAKELGAIIAPNFAIGAILMMKFAQTAARYMNDVEIIEQHHDRKLDAP
SGTAVKTAQLIAEVRAPKKQGHEQEREEMAGARGADFDGMKIHSVRLPGRVAHQEVLFGGVGQTLSIRHDSLNRESFMPG
VKLAVEQVVKLSTLVYGLENLID

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=279, Percent_Identity=29.3906810035842, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_BACSK (Q5WGQ4)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175412.1
- ProteinModelPortal:   Q5WGQ4
- SMR:   Q5WGQ4
- STRING:   Q5WGQ4
- EnsemblBacteria:   EBBACT00000048020
- GeneID:   3203886
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1916
- NMPDR:   fig|66692.3.peg.1960
- eggNOG:   COG0289
- GeneTree:   EBGT00050000002586
- HOGENOM:   HBG594002
- OMA:   ARFYDHA
- ProtClustDB:   PRK00048
- BioCyc:   BCLA66692:ABC1916-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29014; Mature: 28882

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIVIAGPRGNMGQEAVKLCLREESFELVAVVDSKNDGKQLKGLQEFQQGDVPVYTDMA
CCEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHH
RCFAEHEPDVLIDLTAPAFGRKHMEVAFEHGVRPVVGTTGFSDEDIRDLTKLAEAKELGA
HHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
IIAPNFAIGAILMMKFAQTAARYMNDVEIIEQHHDRKLDAPSGTAVKTAQLIAEVRAPKK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHH
QGHEQEREEMAGARGADFDGMKIHSVRLPGRVAHQEVLFGGVGQTLSIRHDSLNRESFMP
CCHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCHHHCCC
GVKLAVEQVVKLSTLVYGLENLID
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRIVIAGPRGNMGQEAVKLCLREESFELVAVVDSKNDGKQLKGLQEFQQGDVPVYTDMA
CEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHH
RCFAEHEPDVLIDLTAPAFGRKHMEVAFEHGVRPVVGTTGFSDEDIRDLTKLAEAKELGA
HHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
IIAPNFAIGAILMMKFAQTAARYMNDVEIIEQHHDRKLDAPSGTAVKTAQLIAEVRAPKK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHH
QGHEQEREEMAGARGADFDGMKIHSVRLPGRVAHQEVLFGGVGQTLSIRHDSLNRESFMP
CCHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCHHHCCC
GVKLAVEQVVKLSTLVYGLENLID
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA