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The map label for this gene is aroF

Identifier: 56963657

GI number: 56963657

Start: 2008884

End: 2010056

Strand: Direct

Name: aroF

Synonym: ABC1892

Alternate gene names: 56963657

Gene position: 2008884-2010056 (Clockwise)

Preceding gene: 56963656

Following gene: 56963658

Centisome position: 46.68

GC content: 49.7

Gene sequence:

>1173_bases
TTGAGATTTTTAACAGCAGGAGAGTCACATGGACCACAACTGACTGCGATTATTGAAGGCGTGCCAGCGCAATTGCCGCT
TTTGGCAGAAGATATTGACCGTGAATTGGCTAGGCGCCAAGGCGGTTACGGCCGTGGTCGCCGTATGCAAATTGAAAAAG
ACCGCGTTCAAATAGTAAGCGGCGTACGCCATGGCATGACGACTGGTGCCCCTATCACATTTGTTGTCGAAAATAAAGAC
TGGAAAAATTGGACAAAAATAATGGGCGCTGAACCGATAAGTGAGGAAGAAGCGGAAAAAATGAGACGGAAGTTAACACG
TCCCCGTCCAGGTCATGCTGATTTAAATGGTGCAATCAAGTACGGGCACCGCGATATGCGCAATGTTTTAGAGCGTTCAT
CAGCGCGGGAAACGACTGTCCGTGTTGCCTGTGGAGCATTGGCAAAGGTCATCCTTAAAGCTTGTGGCATTGAAGTTGCC
GGACATGTCCGCGAAATTGGCGGCATTCGGGCTGAGGAAACAAACTATGCCACGATCCAAGAATTGCAAAAGCGCTCAGA
AGAGTCACCTGTACGCTGTTTAGACGAGGATGCAAGCAAAAAGATGATGGCAGCCATTGACAAGGCAAAACAAGATGGTG
ATTCGATTGGCGGCATAGTTGAAGTCGTTGTTGCTGGCGTGCCTATTGGCCTCGGCAGCCATGTCCATTATGACCGCAAA
TTGGATGGCAAAATCGCTGGCGCAGTCATGAGCATCAACGCGTTTAAAGGTGTAGAGATTGGCATTGGCTTTGAGGCAGC
GCGGCTTCCAGGCAGCCAAGTTCATGATGAGATTACTTGGAGCGAAGAGGAAGGCTATAAGCGGAAGACGAATCGCCTTG
GCGGTTTTGAAGGCGGGATGACCAACGGTATGCCGATTGTCGTAAAAGGTGTGATGAAGCCAATCCCAACGTTGTATAAG
CCGCTGCAAAGCGTAGATATTGATTCGAAAGAACCATTTGCCGCAGGTGTTGAACGTTCCGATAGCTGTGCCGTTCCCGC
TGCATCGGTTGTCTGCGAAAATGTGGTAGCGTGGGAAGTTGCCAATGCCTTGCTTGATACATTTGGTTCTGACCAGCTTC
CTCTGATCCAGGCAGCTGTCGAACGTCACCATGCCGCTTCAAAGGAGTTTTAA

Upstream 100 bases:

>100_bases
AAAGTAACATGAATGTACAGACAATTGCTCCAATACATGCTATAATTTAACGCATAAAAGCGATAAAGTATTGCCGGCAA
GATAGGAAAGGGTGTTAACA

Downstream 100 bases:

>100_bases
ACGATGTTTGTAGACATTCACACCTCTTCAAAACAATACAAGGCTGAAGTGGGGTCAGGAATTTTGCGGGAGGCAGGCAA
AACGATTGAAGCGCTTGCCC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MRFLTAGESHGPQLTAIIEGVPAQLPLLAEDIDRELARRQGGYGRGRRMQIEKDRVQIVSGVRHGMTTGAPITFVVENKD
WKNWTKIMGAEPISEEEAEKMRRKLTRPRPGHADLNGAIKYGHRDMRNVLERSSARETTVRVACGALAKVILKACGIEVA
GHVREIGGIRAEETNYATIQELQKRSEESPVRCLDEDASKKMMAAIDKAKQDGDSIGGIVEVVVAGVPIGLGSHVHYDRK
LDGKIAGAVMSINAFKGVEIGIGFEAARLPGSQVHDEITWSEEEGYKRKTNRLGGFEGGMTNGMPIVVKGVMKPIPTLYK
PLQSVDIDSKEPFAAGVERSDSCAVPAASVVCENVVAWEVANALLDTFGSDQLPLIQAAVERHHAASKEF

Sequences:

>Translated_390_residues
MRFLTAGESHGPQLTAIIEGVPAQLPLLAEDIDRELARRQGGYGRGRRMQIEKDRVQIVSGVRHGMTTGAPITFVVENKD
WKNWTKIMGAEPISEEEAEKMRRKLTRPRPGHADLNGAIKYGHRDMRNVLERSSARETTVRVACGALAKVILKACGIEVA
GHVREIGGIRAEETNYATIQELQKRSEESPVRCLDEDASKKMMAAIDKAKQDGDSIGGIVEVVVAGVPIGLGSHVHYDRK
LDGKIAGAVMSINAFKGVEIGIGFEAARLPGSQVHDEITWSEEEGYKRKTNRLGGFEGGMTNGMPIVVKGVMKPIPTLYK
PLQSVDIDSKEPFAAGVERSDSCAVPAASVVCENVVAWEVANALLDTFGSDQLPLIQAAVERHHAASKEF
>Mature_390_residues
MRFLTAGESHGPQLTAIIEGVPAQLPLLAEDIDRELARRQGGYGRGRRMQIEKDRVQIVSGVRHGMTTGAPITFVVENKD
WKNWTKIMGAEPISEEEAEKMRRKLTRPRPGHADLNGAIKYGHRDMRNVLERSSARETTVRVACGALAKVILKACGIEVA
GHVREIGGIRAEETNYATIQELQKRSEESPVRCLDEDASKKMMAAIDKAKQDGDSIGGIVEVVVAGVPIGLGSHVHYDRK
LDGKIAGAVMSINAFKGVEIGIGFEAARLPGSQVHDEITWSEEEGYKRKTNRLGGFEGGMTNGMPIVVKGVMKPIPTLYK
PLQSVDIDSKEPFAAGVERSDSCAVPAASVVCENVVAWEVANALLDTFGSDQLPLIQAAVERHHAASKEF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=366, Percent_Identity=37.431693989071, Blast_Score=179, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6321290, Length=374, Percent_Identity=34.4919786096257, Blast_Score=184, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_BACSK (Q5WGS8)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175388.1
- ProteinModelPortal:   Q5WGS8
- SMR:   Q5WGS8
- STRING:   Q5WGS8
- EnsemblBacteria:   EBBACT00000046971
- GeneID:   3201726
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1892
- NMPDR:   fig|66692.3.peg.1936
- eggNOG:   COG0082
- GeneTree:   EBGT00050000002373
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BioCyc:   BCLA66692:ABC1892-MONOMER
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42379; Mature: 42379

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLTAGESHGPQLTAIIEGVPAQLPLLAEDIDRELARRQGGYGRGRRMQIEKDRVQIVS
CCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHH
GVRHGMTTGAPITFVVENKDWKNWTKIMGAEPISEEEAEKMRRKLTRPRPGHADLNGAIK
HHHHCCCCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHH
YGHRDMRNVLERSSARETTVRVACGALAKVILKACGIEVAGHVREIGGIRAEETNYATIQ
HCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHH
ELQKRSEESPVRCLDEDASKKMMAAIDKAKQDGDSIGGIVEVVVAGVPIGLGSHVHYDRK
HHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
LDGKIAGAVMSINAFKGVEIGIGFEAARLPGSQVHDEITWSEEEGYKRKTNRLGGFEGGM
CCCHHHHHEEEEECCCCEEEECCCHHHCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
TNGMPIVVKGVMKPIPTLYKPLQSVDIDSKEPFAAGVERSDSCAVPAASVVCENVVAWEV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ANALLDTFGSDQLPLIQAAVERHHAASKEF
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRFLTAGESHGPQLTAIIEGVPAQLPLLAEDIDRELARRQGGYGRGRRMQIEKDRVQIVS
CCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHH
GVRHGMTTGAPITFVVENKDWKNWTKIMGAEPISEEEAEKMRRKLTRPRPGHADLNGAIK
HHHHCCCCCCCEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHH
YGHRDMRNVLERSSARETTVRVACGALAKVILKACGIEVAGHVREIGGIRAEETNYATIQ
HCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHH
ELQKRSEESPVRCLDEDASKKMMAAIDKAKQDGDSIGGIVEVVVAGVPIGLGSHVHYDRK
HHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
LDGKIAGAVMSINAFKGVEIGIGFEAARLPGSQVHDEITWSEEEGYKRKTNRLGGFEGGM
CCCHHHHHEEEEECCCCEEEECCCHHHCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
TNGMPIVVKGVMKPIPTLYKPLQSVDIDSKEPFAAGVERSDSCAVPAASVVCENVVAWEV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ANALLDTFGSDQLPLIQAAVERHHAASKEF
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA