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The map label for this gene is gpsA

Identifier: 56963643

GI number: 56963643

Start: 1997646

End: 1998668

Strand: Direct

Name: gpsA

Synonym: ABC1878

Alternate gene names: 56963643

Gene position: 1997646-1998668 (Clockwise)

Preceding gene: 56963642

Following gene: 56963644

Centisome position: 46.42

GC content: 47.31

Gene sequence:

>1023_bases
ATGCAAAAAATTGCGGTGATTGGAGCGGGAAGCTGGGGAAGCGCTTTAGCGATGGTTCTCGCGGATAATGGCCATGATGT
TCGCCTCGTCGGGCGCCGACAAGAACAAATGGACGAATTGAACGAACGTCATACAAATGAATCATATTTGCCGAACATCG
AATTGCCAACAACGATTCGCGGTTATACAGGGATGGAGGAAGCGCTTGGTGGAGTTGAAGCTATCGTACTAGTCGTTCCG
ACTAAAGCGATGCGTGAAACTGTCCGTAAAATCGTGCCCTATTTGCAAAAGGCGGTACCGGTTATTCACGCAAGCAAAGG
GATTGAACCTGCGACTCATAAGCGGATATCTGAAATGATCGCTGAAGAAGATGCAAGCACAAATCGCATTTCTTCTATCA
CCGTTTTATCTGGTCCCAGTCATGCCGAAGAAGTCGCATTGCGCCAACCGACAACCGTTACAGTTGCTTCAGCGGATGAT
GAGGCAGCCAAGTATACGCAAAATTTGTTTATGAACCAACAGTTTCGTGTCTATACCAACCCTGACTTGATCGGCGTTGA
AATCGGAGGGGCACTAAAAAACATTATTGCACTAGCCTGTGGTGTGACAAATGGCCTTGGTTACGGGGACAATACAAAAG
CAGCGATCATGACGAGAGGATTAGCGGAAATCTCTCGCTTAGGCACGACAATGGGCGCCAAACCATTAACGTTTTCCGGT
TTGTCAGGGCTCGGCGATTTAATCGTTACTTGCACAAGTGTGCATTCACGTAACTGGCGTGCTGGACGAATGATTGGCGA
AGGTTTGTCCATGGATGAAGTGCTTGAAAAAATGGGAATGGTAGTCGAAGGAATTCGAACAACCCAGGCAGCCTATGAAC
TATCCGAAAAGCTGGAGATTGATATGCCAGTGACCAAAGCGCTCTATAGTGTCTTGTTTAACGGAATCGACCCTTACCAA
GCGGCTGAAGAATTAATGGGACGTGTAAAACGACATGAAGTGGAGTCGCTTTACCGTTCGTAA

Upstream 100 bases:

>100_bases
GGCCATCTTATCTTTATGGCGGCACCGCACGAACATGGGGCGGCTTATTGCAGGCACGGAAAACAAATTAGGGAAAAAAC
ATGCATAGGAGGAGTTCATA

Downstream 100 bases:

>100_bases
ACGTGGTGGTTAGTTCGTTTTGATTGCGTCTAAATTGCGCACACTCTTTTTTTCTCATGCATACGATAAGGAGAACCGTA
AGCATGAGGAGGGATTTAGG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MQKIAVIGAGSWGSALAMVLADNGHDVRLVGRRQEQMDELNERHTNESYLPNIELPTTIRGYTGMEEALGGVEAIVLVVP
TKAMRETVRKIVPYLQKAVPVIHASKGIEPATHKRISEMIAEEDASTNRISSITVLSGPSHAEEVALRQPTTVTVASADD
EAAKYTQNLFMNQQFRVYTNPDLIGVEIGGALKNIIALACGVTNGLGYGDNTKAAIMTRGLAEISRLGTTMGAKPLTFSG
LSGLGDLIVTCTSVHSRNWRAGRMIGEGLSMDEVLEKMGMVVEGIRTTQAAYELSEKLEIDMPVTKALYSVLFNGIDPYQ
AAEELMGRVKRHEVESLYRS

Sequences:

>Translated_340_residues
MQKIAVIGAGSWGSALAMVLADNGHDVRLVGRRQEQMDELNERHTNESYLPNIELPTTIRGYTGMEEALGGVEAIVLVVP
TKAMRETVRKIVPYLQKAVPVIHASKGIEPATHKRISEMIAEEDASTNRISSITVLSGPSHAEEVALRQPTTVTVASADD
EAAKYTQNLFMNQQFRVYTNPDLIGVEIGGALKNIIALACGVTNGLGYGDNTKAAIMTRGLAEISRLGTTMGAKPLTFSG
LSGLGDLIVTCTSVHSRNWRAGRMIGEGLSMDEVLEKMGMVVEGIRTTQAAYELSEKLEIDMPVTKALYSVLFNGIDPYQ
AAEELMGRVKRHEVESLYRS
>Mature_340_residues
MQKIAVIGAGSWGSALAMVLADNGHDVRLVGRRQEQMDELNERHTNESYLPNIELPTTIRGYTGMEEALGGVEAIVLVVP
TKAMRETVRKIVPYLQKAVPVIHASKGIEPATHKRISEMIAEEDASTNRISSITVLSGPSHAEEVALRQPTTVTVASADD
EAAKYTQNLFMNQQFRVYTNPDLIGVEIGGALKNIIALACGVTNGLGYGDNTKAAIMTRGLAEISRLGTTMGAKPLTFSG
LSGLGDLIVTCTSVHSRNWRAGRMIGEGLSMDEVLEKMGMVVEGIRTTQAAYELSEKLEIDMPVTKALYSVLFNGIDPYQ
AAEELMGRVKRHEVESLYRS

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=356, Percent_Identity=28.3707865168539, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI24307999, Length=354, Percent_Identity=28.5310734463277, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1790037, Length=334, Percent_Identity=41.3173652694611, Blast_Score=273, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI32564399, Length=346, Percent_Identity=30.635838150289, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI193210136, Length=353, Percent_Identity=30.028328611898, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32564403, Length=360, Percent_Identity=30, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17507425, Length=355, Percent_Identity=27.6056338028169, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193210134, Length=345, Percent_Identity=27.2463768115942, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324513, Length=346, Percent_Identity=29.1907514450867, Blast_Score=131, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320181, Length=363, Percent_Identity=28.3746556473829, Blast_Score=123, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17136204, Length=348, Percent_Identity=28.735632183908, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17136202, Length=348, Percent_Identity=28.735632183908, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17136200, Length=348, Percent_Identity=28.735632183908, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI22026922, Length=358, Percent_Identity=25.6983240223464, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45551945, Length=261, Percent_Identity=26.0536398467433, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281362270, Length=261, Percent_Identity=26.0536398467433, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648969, Length=275, Percent_Identity=24, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_BACSK (Q5WGU2)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175374.1
- ProteinModelPortal:   Q5WGU2
- SMR:   Q5WGU2
- STRING:   Q5WGU2
- EnsemblBacteria:   EBBACT00000049451
- GeneID:   3204545
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1878
- NMPDR:   fig|66692.3.peg.1922
- eggNOG:   COG0240
- GeneTree:   EBGT00050000002224
- HOGENOM:   HBG586392
- OMA:   NYRVGYG
- ProtClustDB:   PRK00094
- BioCyc:   BCLA66692:ABC1878-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 36892; Mature: 36892

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 193-193 BINDING 106-106 BINDING 106-106 BINDING 142-142 BINDING 257-257 BINDING 283-283

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIAVIGAGSWGSALAMVLADNGHDVRLVGRRQEQMDELNERHTNESYLPNIELPTTIR
CCEEEEEECCCHHHHEEEEEECCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GYTGMEEALGGVEAIVLVVPTKAMRETVRKIVPYLQKAVPVIHASKGIEPATHKRISEMI
CCCCHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AEEDASTNRISSITVLSGPSHAEEVALRQPTTVTVASADDEAAKYTQNLFMNQQFRVYTN
HHCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEC
PDLIGVEIGGALKNIIALACGVTNGLGYGDNTKAAIMTRGLAEISRLGTTMGAKPLTFSG
CCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECC
LSGLGDLIVTCTSVHSRNWRAGRMIGEGLSMDEVLEKMGMVVEGIRTTQAAYELSEKLEI
CCHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DMPVTKALYSVLFNGIDPYQAAEELMGRVKRHEVESLYRS
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKIAVIGAGSWGSALAMVLADNGHDVRLVGRRQEQMDELNERHTNESYLPNIELPTTIR
CCEEEEEECCCHHHHEEEEEECCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GYTGMEEALGGVEAIVLVVPTKAMRETVRKIVPYLQKAVPVIHASKGIEPATHKRISEMI
CCCCHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AEEDASTNRISSITVLSGPSHAEEVALRQPTTVTVASADDEAAKYTQNLFMNQQFRVYTN
HHCCCCCCCEEEEEEECCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEC
PDLIGVEIGGALKNIIALACGVTNGLGYGDNTKAAIMTRGLAEISRLGTTMGAKPLTFSG
CCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEECC
LSGLGDLIVTCTSVHSRNWRAGRMIGEGLSMDEVLEKMGMVVEGIRTTQAAYELSEKLEI
CCHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DMPVTKALYSVLFNGIDPYQAAEELMGRVKRHEVESLYRS
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA