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The map label for this gene is prsW

Identifier: 56963630

GI number: 56963630

Start: 1982155

End: 1982802

Strand: Direct

Name: prsW

Synonym: ABC1865

Alternate gene names: 56963630

Gene position: 1982155-1982802 (Clockwise)

Preceding gene: 56963629

Following gene: 56963631

Centisome position: 46.06

GC content: 43.98

Gene sequence:

>648_bases
ATGGTATCCCTTGTTCTAGCTGCACTGGCTCCGGCCATGGCATTGTTTTCATATGTCTATTTGCGCGATGTATACAGCAA
AGCAAAAATGTTTCTCGTTCTCCGGATTTTCATTATCGGCGCACTGCTAGTCGTGCCGATTTTGGTGATCCAGTTTGCCT
TTACTGAAGAAAATGTCTTTCCCCATCCAGCGGCTAAAGCGTTTTTGCTTTACGGGTTTCTGGAAGAAGGGTTAAAATGG
CTCATGTTGTTTGTATTTGCCTACCAACATGGACAGCTTCAGCGCCCAGGGGACGGCATTTTGTTCGGTGTTTCCGTCTC
CCTTGGCTTTGCTACAGTTGAAAATGGCTTATACATGATCGCTTATGGGTTAGAGGCAGCCATCCCACGAACTGTTTTGC
CAACAACGGCACATGCTGTTTACGGGATTGTGATGGGCTATTACATTGGACAAGCGAAGTACAAAGAAGACCATAAAAAA
ATGTTTTTACTCCTTGGGGCGATTCTGCCAATCCTATTGCATGGCGGATATGATTTTATTTTATCAAGCTTTGGCCATTA
CGTCCTTTATGCGATGATTCCATTTATGGTCATTCTTTGGCTTCTCGCGATATGGAAGCTGAAAAAAGCAAGCCGTTTTA
CTGTTTAA

Upstream 100 bases:

>100_bases
CTGGGTTTACGTGATGGCGCTTGCTGATCGGAACAAGCCGGTTTTATACTAGAAAAAAGGAATGTTCTATTAGCGAACCA
AAGAGAGTAGGCGGTCAGCC

Downstream 100 bases:

>100_bases
AATCACTAGACCGATACGCTTGTCAAACGATCTTGTATGCGAGCGTTTGTCTACAGCCTAAAAGCCGTTTCACTGTGTAA
GCGAACATTTAACACGAAGG

Product: hypothetical protein

Products: NA

Alternate protein names: Protease responsible for activating sigma-W

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MVSLVLAALAPAMALFSYVYLRDVYSKAKMFLVLRIFIIGALLVVPILVIQFAFTEENVFPHPAAKAFLLYGFLEEGLKW
LMLFVFAYQHGQLQRPGDGILFGVSVSLGFATVENGLYMIAYGLEAAIPRTVLPTTAHAVYGIVMGYYIGQAKYKEDHKK
MFLLLGAILPILLHGGYDFILSSFGHYVLYAMIPFMVILWLLAIWKLKKASRFTV

Sequences:

>Translated_215_residues
MVSLVLAALAPAMALFSYVYLRDVYSKAKMFLVLRIFIIGALLVVPILVIQFAFTEENVFPHPAAKAFLLYGFLEEGLKW
LMLFVFAYQHGQLQRPGDGILFGVSVSLGFATVENGLYMIAYGLEAAIPRTVLPTTAHAVYGIVMGYYIGQAKYKEDHKK
MFLLLGAILPILLHGGYDFILSSFGHYVLYAMIPFMVILWLLAIWKLKKASRFTV
>Mature_215_residues
MVSLVLAALAPAMALFSYVYLRDVYSKAKMFLVLRIFIIGALLVVPILVIQFAFTEENVFPHPAAKAFLLYGFLEEGLKW
LMLFVFAYQHGQLQRPGDGILFGVSVSLGFATVENGLYMIAYGLEAAIPRTVLPTTAHAVYGIVMGYYIGQAKYKEDHKK
MFLLLGAILPILLHGGYDFILSSFGHYVLYAMIPFMVILWLLAIWKLKKASRFTV

Specific function: Is responsible for Site-1 cleavage of the RsiW anti- sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sig

COG id: COG2339

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease prsW family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRSW_BACSK (Q5WGV5)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175361.1
- ProteinModelPortal:   Q5WGV5
- STRING:   Q5WGV5
- EnsemblBacteria:   EBBACT00000045990
- GeneID:   3202997
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1865
- NMPDR:   fig|66692.3.peg.21
- eggNOG:   COG2339
- GeneTree:   EBGT00050000001164
- HOGENOM:   HBG549045
- OMA:   DEPYDGI
- ProtClustDB:   CLSK873083
- BioCyc:   BCLA66692:ABC1865-MONOMER

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24114; Mature: 24114

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d9c12e8)-; HASH(0x1db2951c)-; HASH(0x1dadb420)-; HASH(0x1d0b63ec)-; HASH(0x1d9a564c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLVLAALAPAMALFSYVYLRDVYSKAKMFLVLRIFIIGALLVVPILVIQFAFTEENVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PHPAAKAFLLYGFLEEGLKWLMLFVFAYQHGQLQRPGDGILFGVSVSLGFATVENGLYMI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHCCEEEE
AYGLEAAIPRTVLPTTAHAVYGIVMGYYIGQAKYKEDHKKMFLLLGAILPILLHGGYDFI
EECHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LSSFGHYVLYAMIPFMVILWLLAIWKLKKASRFTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MVSLVLAALAPAMALFSYVYLRDVYSKAKMFLVLRIFIIGALLVVPILVIQFAFTEENVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PHPAAKAFLLYGFLEEGLKWLMLFVFAYQHGQLQRPGDGILFGVSVSLGFATVENGLYMI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHCCEEEE
AYGLEAAIPRTVLPTTAHAVYGIVMGYYIGQAKYKEDHKKMFLLLGAILPILLHGGYDFI
EECHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LSSFGHYVLYAMIPFMVILWLLAIWKLKKASRFTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA