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The map label for this gene is mshA [H]

Identifier: 56963617

GI number: 56963617

Start: 1968071

End: 1969291

Strand: Direct

Name: mshA [H]

Synonym: ABC1852

Alternate gene names: 56963617

Gene position: 1968071-1969291 (Clockwise)

Preceding gene: 56963616

Following gene: 56963618

Centisome position: 45.73

GC content: 44.64

Gene sequence:

>1221_bases
ATGAATATTGGGATCTTTACCGACACCTATTTTCCGCAAATTAGCGGGGTGGCTTCGTCTATTGCAACACTTGAAAAAGA
ATTGAGCGCCCGGGGTCATCGCGTTTACATTTTTACCTCAACGGATAAAGCGGCAGATCCAGAACAGGAGGAGGGGAAGG
TTTTTCGGTTTTCAAGCCTTGCTGTTGGATTTGTGCCCGAACGACGCTTAGCTTACGCTGGGATACGCAGAGCGACAAAA
CTGATGAAGGAACTAAACATCGAAATCGTCCATACCCACACAGAATTTACAATGGGATGCTTAGGAAAGCATCTTGCACA
TAAATGTAAGCTTCCTCACATTCATACATACCACACGATGTATGAAGACTATGTTCATTACATTGCACGAGGAAAGCTGT
TGTCTCCGAAAATGGTTGGCCGTTTAACAAAATGGTTTTGCCGCGGTGCTGATGCTGTCATTGCACCTACGGAAAAAGTG
AAGACCTATTTGCGCCGTTATAAAGTGAGCGAACCAATTTATGTCATCCCGACAGGCGTCTCAGTGAAGCAGTTTAAACG
TTCTGAAGCAAGCTTGGTGGATGTGTTGGCGTTAAGGAAAAAACTTGCGATCAATGAAAGTGACAAAGTCATTATTAGCA
TTGGCCGGATGGCAGAAGAAAAAAACATGGAGGCGCTCTTGTACGCAATCAAATCATTGGAGAGCGAATTGGATCATGTG
AAAACGGTGATGGTTGGAGACGGGCCTGTCCGAAAGTCTCTTGAAGCGCTGGCTGTATCCCTTGGAATTAGCGAGCATGT
CCGCTTTACTGGTGCTGTTGAGTGGAACCAGATCCACCATTACTACCATTTAGGTGATTTGTTCGTAAGTGCGTCGACGA
CTGAAGCGCAAGGCCTTACCTATATTGAAGCAATGGCTTCAGGCTGCATTGTAGTGGCCAAGTCTGATCCAAGTATTAAA
CGGATTGTCTTAGACGGCACAACTGGTTTTGTATTTAAAGAAGATGAGGATCTTGGACCACTTTTGCGCCGTTTGCTGCA
CTCATCCCATTTATCGAAAGTGCGCAAAGCTGCCAAGAAACAAATTCAGCCATTAACCGCAGAAGCGTTTGGCGCCAAAG
TAGAACAAACTTATTTTGAGCTCGCCAAAAACAAAAAAATCGAAAACAGTTCGCCTAAACTTAGGCAAGCAATCCTTTAT
CGAAAAGAGCAGTCATTATGA

Upstream 100 bases:

>100_bases
GAAATGGGATCTTTCTTCTTTTATTGGCAAGAAGCTTTATACTTTACTAGTGTTCTATTGAGAAAGTAAGCTCCATTTCA
GAAAAGGAAAGAGGAATAAC

Downstream 100 bases:

>100_bases
TTAAACTCGAAATGTTATCGTCTGCAGAAAAAGTAAAAGGGCAGGGGGTCGCCTCTGCCTACCGGGAACTAGTCAACGTT
CTGGAGCGAAAAGCACAACA

Product: glycosyltransferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNIGIFTDTYFPQISGVASSIATLEKELSARGHRVYIFTSTDKAADPEQEEGKVFRFSSLAVGFVPERRLAYAGIRRATK
LMKELNIEIVHTHTEFTMGCLGKHLAHKCKLPHIHTYHTMYEDYVHYIARGKLLSPKMVGRLTKWFCRGADAVIAPTEKV
KTYLRRYKVSEPIYVIPTGVSVKQFKRSEASLVDVLALRKKLAINESDKVIISIGRMAEEKNMEALLYAIKSLESELDHV
KTVMVGDGPVRKSLEALAVSLGISEHVRFTGAVEWNQIHHYYHLGDLFVSASTTEAQGLTYIEAMASGCIVVAKSDPSIK
RIVLDGTTGFVFKEDEDLGPLLRRLLHSSHLSKVRKAAKKQIQPLTAEAFGAKVEQTYFELAKNKKIENSSPKLRQAILY
RKEQSL

Sequences:

>Translated_406_residues
MNIGIFTDTYFPQISGVASSIATLEKELSARGHRVYIFTSTDKAADPEQEEGKVFRFSSLAVGFVPERRLAYAGIRRATK
LMKELNIEIVHTHTEFTMGCLGKHLAHKCKLPHIHTYHTMYEDYVHYIARGKLLSPKMVGRLTKWFCRGADAVIAPTEKV
KTYLRRYKVSEPIYVIPTGVSVKQFKRSEASLVDVLALRKKLAINESDKVIISIGRMAEEKNMEALLYAIKSLESELDHV
KTVMVGDGPVRKSLEALAVSLGISEHVRFTGAVEWNQIHHYYHLGDLFVSASTTEAQGLTYIEAMASGCIVVAKSDPSIK
RIVLDGTTGFVFKEDEDLGPLLRRLLHSSHLSKVRKAAKKQIQPLTAEAFGAKVEQTYFELAKNKKIENSSPKLRQAILY
RKEQSL
>Mature_406_residues
MNIGIFTDTYFPQISGVASSIATLEKELSARGHRVYIFTSTDKAADPEQEEGKVFRFSSLAVGFVPERRLAYAGIRRATK
LMKELNIEIVHTHTEFTMGCLGKHLAHKCKLPHIHTYHTMYEDYVHYIARGKLLSPKMVGRLTKWFCRGADAVIAPTEKV
KTYLRRYKVSEPIYVIPTGVSVKQFKRSEASLVDVLALRKKLAINESDKVIISIGRMAEEKNMEALLYAIKSLESELDHV
KTVMVGDGPVRKSLEALAVSLGISEHVRFTGAVEWNQIHHYYHLGDLFVSASTTEAQGLTYIEAMASGCIVVAKSDPSIK
RIVLDGTTGFVFKEDEDLGPLLRRLLHSSHLSKVRKAAKKQIQPLTAEAFGAKVEQTYFELAKNKKIENSSPKLRQAILY
RKEQSL

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=324, Percent_Identity=24.6913580246914, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17532709, Length=326, Percent_Identity=22.3926380368098, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI9755344, Length=354, Percent_Identity=24.5762711864407, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654571, Length=338, Percent_Identity=21.8934911242604, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 45597; Mature: 45597

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIFTDTYFPQISGVASSIATLEKELSARGHRVYIFTSTDKAADPEQEEGKVFRFSSL
CCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECE
AVGFVPERRLAYAGIRRATKLMKELNIEIVHTHTEFTMGCLGKHLAHKCKLPHIHTYHTM
EEECCCCHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHH
YEDYVHYIARGKLLSPKMVGRLTKWFCRGADAVIAPTEKVKTYLRRYKVSEPIYVIPTGV
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCCCEEEEECCC
SVKQFKRSEASLVDVLALRKKLAINESDKVIISIGRMAEEKNMEALLYAIKSLESELDHV
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCHHHHHHHHHHHHHHHHHH
KTVMVGDGPVRKSLEALAVSLGISEHVRFTGAVEWNQIHHYYHLGDLFVSASTTEAQGLT
EEEEECCCHHHHHHHHHHHHCCCHHHEEEEEEEEHHHHHHEEEECCEEEECCCCCCCCHH
YIEAMASGCIVVAKSDPSIKRIVLDGTTGFVFKEDEDLGPLLRRLLHSSHLSKVRKAAKK
HHHHHHCCEEEEEECCCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
QIQPLTAEAFGAKVEQTYFELAKNKKIENSSPKLRQAILYRKEQSL
HCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIGIFTDTYFPQISGVASSIATLEKELSARGHRVYIFTSTDKAADPEQEEGKVFRFSSL
CCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECE
AVGFVPERRLAYAGIRRATKLMKELNIEIVHTHTEFTMGCLGKHLAHKCKLPHIHTYHTM
EEECCCCHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHH
YEDYVHYIARGKLLSPKMVGRLTKWFCRGADAVIAPTEKVKTYLRRYKVSEPIYVIPTGV
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCCCEEEEECCC
SVKQFKRSEASLVDVLALRKKLAINESDKVIISIGRMAEEKNMEALLYAIKSLESELDHV
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCHHHHHHHHHHHHHHHHHH
KTVMVGDGPVRKSLEALAVSLGISEHVRFTGAVEWNQIHHYYHLGDLFVSASTTEAQGLT
EEEEECCCHHHHHHHHHHHHCCCHHHEEEEEEEEHHHHHHEEEECCEEEECCCCCCCCHH
YIEAMASGCIVVAKSDPSIKRIVLDGTTGFVFKEDEDLGPLLRRLLHSSHLSKVRKAAKK
HHHHHHCCEEEEEECCCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
QIQPLTAEAFGAKVEQTYFELAKNKKIENSSPKLRQAILYRKEQSL
HCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA