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The map label for this gene is resE [H]

Identifier: 56963601

GI number: 56963601

Start: 1952786

End: 1954582

Strand: Direct

Name: resE [H]

Synonym: ABC1836

Alternate gene names: 56963601

Gene position: 1952786-1954582 (Clockwise)

Preceding gene: 56963600

Following gene: 56963602

Centisome position: 45.37

GC content: 46.41

Gene sequence:

>1797_bases
GTGATGCTGTGGCAAAGTGTAGTCGGGAAATTATGGTTTACCATCCTTTTGCTTGTCACAGCTGTATTGACAATTCTAAT
GGTGCTGCTGCTTCGCTTTACAGAAGGAAATGCAATTGAGGAAGCTGAAAGCCGCTTAAACAGCTACGCAAATATGGCAA
AAACGATGTATGAAACCCATACGGATGAAACAAGCACGTATGATTACTTGCAATCGTTAAGCAATGAATTCCAAATTAAT
ATCACCATTATTAAAAATGGCGCAAAAGCGTGGAGTGCCCAAGGCAACCGTTCAGGCGAGATCAATGTTGCGACATTGCT
GGAAGAGTGGTCGGTAGAAGGACTTGAAAAAGGCGAGCGGATTGTAACAGAGGCCAATTATCCTGCCAGTGGACAGGAGC
AAGACCCGATTGAAATGATCGTTGTCGGTGTGCCGTTATCAGAAGATTATTTAACGAGCAGCGGCATCATTTTATACCAA
CCACTGTCTGCCGTCGAGGAAGCAGCTGCAGAAACGCGACGGATTATCTATTTGTCAGCAGGCATTGCGTTAGTGTTGAC
GACTGTTTTTGCGTTTTTTTTGTCAAGTCGGATCACGGCACCGCTGCGAAAAATGCGGCAAGCGGCATTGGAAGTGGCAC
AAGGGCAGTTTCATACGAAAGTGCCGATCCTTACACAAGATGAGATTGGCCAGCTAGCGATTGCCTTTAACCGGATGCGC
CGAGAGCTCAATCGCAACATTTCCGAGTTGAATCAAGAAAAAGAACAGCTTTCCCATATTCTCGCCTCAATGGCTGACGG
CGTGATTACACTAGACCGACAAGGCAGAATCTTATTGACCAACCCCCAAGCAGAGGAAGTGTTAGCGCTGCTCTTCTATG
AAGAGGGGCAAAAGCCAATAACGGGTGAACGGAAAACATTGCCAGTATCGTTAACACCTTTGTTTGAACAAGTCGTTTCA
GCGGAGAAAGAAGAGCTGCAAGAACTGTCCGTTCAAGGGCGAAGTATGGCTGTGTTGATGGCGCCTCTCTATGCTGAAGA
GCATGTCCGTGGTGCTGTAGCTGTTGTCCGTGATGTAACGGAAGAGCGCCGGCATGACAAATTGCGCAAAGATTTTATTG
CCAACGTGTCGCATGAGCTCAGGACGCCAATCTCAATGTTGCAAGGCTATAGCGAAGCCATGGTTGACGGGGTAACATCA
AGTGATGAGGAACGAAAAGAAGTCGCGCAAATCATTTACGATGAATCGCTACGTATGGGCAGGCTCGTCAATGAGCTTCT
CGATTTGGCACGTATGGAAGCAGGCTATATTGACTTGAATCTGGAAGAAGTGGATCTCGATTCTTATTTAGAACGGATTA
CCCGCAAGTTTGCAAGCTTTGCCCGCGAATATGACGTAACAGTCGAATTGGCCAAGCCAGGAAGAGGACAGATTGCTGTA
TTTGACCCTGACCGGATTGAGCAAGTTTTAACCAATTTAATTCATAATGCGATCAGGCATACAAACCCTGGTGGACTGAT
TACCGTTGTACATGAACAAGAAGAAGAACGTGACACATTTGCTGTAGTTGATACAGGGAGGGGCATTCCTGAAGAAGACC
TTCCTTATGTGTTTGAACGTTTTTATAAAGCGGACAAAGCGCGGACAAGGCAGCATGGCGGAACAGGGCTGGGCCTTGCT
ATTGCGAAACATATTATTGACGCACACCAAGGGAAAATTACTGTCCATAGCCGCTTAGGAGAAGGGACAACATTTCATTT
TACGTTGCCTAAACAGCAAGGCGATAAAGGGAAATGA

Upstream 100 bases:

>100_bases
TCAAACGGTTACGCGAAAAATTGAATCGCGTTTCTCCAGAAGTAGCAGCCATTATTTCAACCGTTTGGGGGGTTGGATAC
AAGTTTGAGGCGACGCGTGG

Downstream 100 bases:

>100_bases
GACATTCTGTGATTAAACAGAGGCAAGCAATGGTATTGCTCAAGTGGATGTGGGCAATGCAGACGGATGCAGCGTTTGTC
GGAATCGACAAGGCGCTGCA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MMLWQSVVGKLWFTILLLVTAVLTILMVLLLRFTEGNAIEEAESRLNSYANMAKTMYETHTDETSTYDYLQSLSNEFQIN
ITIIKNGAKAWSAQGNRSGEINVATLLEEWSVEGLEKGERIVTEANYPASGQEQDPIEMIVVGVPLSEDYLTSSGIILYQ
PLSAVEEAAAETRRIIYLSAGIALVLTTVFAFFLSSRITAPLRKMRQAALEVAQGQFHTKVPILTQDEIGQLAIAFNRMR
RELNRNISELNQEKEQLSHILASMADGVITLDRQGRILLTNPQAEEVLALLFYEEGQKPITGERKTLPVSLTPLFEQVVS
AEKEELQELSVQGRSMAVLMAPLYAEEHVRGAVAVVRDVTEERRHDKLRKDFIANVSHELRTPISMLQGYSEAMVDGVTS
SDEERKEVAQIIYDESLRMGRLVNELLDLARMEAGYIDLNLEEVDLDSYLERITRKFASFAREYDVTVELAKPGRGQIAV
FDPDRIEQVLTNLIHNAIRHTNPGGLITVVHEQEEERDTFAVVDTGRGIPEEDLPYVFERFYKADKARTRQHGGTGLGLA
IAKHIIDAHQGKITVHSRLGEGTTFHFTLPKQQGDKGK

Sequences:

>Translated_598_residues
MMLWQSVVGKLWFTILLLVTAVLTILMVLLLRFTEGNAIEEAESRLNSYANMAKTMYETHTDETSTYDYLQSLSNEFQIN
ITIIKNGAKAWSAQGNRSGEINVATLLEEWSVEGLEKGERIVTEANYPASGQEQDPIEMIVVGVPLSEDYLTSSGIILYQ
PLSAVEEAAAETRRIIYLSAGIALVLTTVFAFFLSSRITAPLRKMRQAALEVAQGQFHTKVPILTQDEIGQLAIAFNRMR
RELNRNISELNQEKEQLSHILASMADGVITLDRQGRILLTNPQAEEVLALLFYEEGQKPITGERKTLPVSLTPLFEQVVS
AEKEELQELSVQGRSMAVLMAPLYAEEHVRGAVAVVRDVTEERRHDKLRKDFIANVSHELRTPISMLQGYSEAMVDGVTS
SDEERKEVAQIIYDESLRMGRLVNELLDLARMEAGYIDLNLEEVDLDSYLERITRKFASFAREYDVTVELAKPGRGQIAV
FDPDRIEQVLTNLIHNAIRHTNPGGLITVVHEQEEERDTFAVVDTGRGIPEEDLPYVFERFYKADKARTRQHGGTGLGLA
IAKHIIDAHQGKITVHSRLGEGTTFHFTLPKQQGDKGK
>Mature_598_residues
MMLWQSVVGKLWFTILLLVTAVLTILMVLLLRFTEGNAIEEAESRLNSYANMAKTMYETHTDETSTYDYLQSLSNEFQIN
ITIIKNGAKAWSAQGNRSGEINVATLLEEWSVEGLEKGERIVTEANYPASGQEQDPIEMIVVGVPLSEDYLTSSGIILYQ
PLSAVEEAAAETRRIIYLSAGIALVLTTVFAFFLSSRITAPLRKMRQAALEVAQGQFHTKVPILTQDEIGQLAIAFNRMR
RELNRNISELNQEKEQLSHILASMADGVITLDRQGRILLTNPQAEEVLALLFYEEGQKPITGERKTLPVSLTPLFEQVVS
AEKEELQELSVQGRSMAVLMAPLYAEEHVRGAVAVVRDVTEERRHDKLRKDFIANVSHELRTPISMLQGYSEAMVDGVTS
SDEERKEVAQIIYDESLRMGRLVNELLDLARMEAGYIDLNLEEVDLDSYLERITRKFASFAREYDVTVELAKPGRGQIAV
FDPDRIEQVLTNLIHNAIRHTNPGGLITVVHEQEEERDTFAVVDTGRGIPEEDLPYVFERFYKADKARTRQHGGTGLGLA
IAKHIIDAHQGKITVHSRLGEGTTFHFTLPKQQGDKGK

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=365, Percent_Identity=31.7808219178082, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=33.1896551724138, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI48994928, Length=249, Percent_Identity=30.9236947791165, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=30.8333333333333, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=30.7017543859649, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788549, Length=448, Percent_Identity=25.6696428571429, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=30.6034482758621, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=32.4444444444444, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=30.8370044052863, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI145693157, Length=369, Percent_Identity=26.2872628726287, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=28.82096069869, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=31.25, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790861, Length=206, Percent_Identity=30.5825242718447, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87081816, Length=233, Percent_Identity=27.8969957081545, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1789808, Length=243, Percent_Identity=28.8065843621399, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=28.7671232876712, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788279, Length=239, Percent_Identity=26.7782426778243, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=241, Percent_Identity=28.6307053941909, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790551, Length=213, Percent_Identity=28.169014084507, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67114; Mature: 67114

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLWQSVVGKLWFTILLLVTAVLTILMVLLLRFTEGNAIEEAESRLNSYANMAKTMYETH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
TDETSTYDYLQSLSNEFQINITIIKNGAKAWSAQGNRSGEINVATLLEEWSVEGLEKGER
CCCCHHHHHHHHCCCCEEEEEEEEECCCHHHCCCCCCCCCCHHHHHHHHHCHHHHHCCCE
IVTEANYPASGQEQDPIEMIVVGVPLSEDYLTSSGIILYQPLSAVEEAAAETRRIIYLSA
EEEECCCCCCCCCCCCEEEEEEECCCCCCHHCCCCEEEECCHHHHHHHHHHHCEEEEEEC
GIALVLTTVFAFFLSSRITAPLRKMRQAALEVAQGQFHTKVPILTQDEIGQLAIAFNRMR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHH
RELNRNISELNQEKEQLSHILASMADGVITLDRQGRILLTNPQAEEVLALLFYEEGQKPI
HHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCC
TGERKTLPVSLTPLFEQVVSAEKEELQELSVQGRSMAVLMAPLYAEEHVRGAVAVVRDVT
CCCCCEECEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
EERRHDKLRKDFIANVSHELRTPISMLQGYSEAMVDGVTSSDEERKEVAQIIYDESLRMG
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RLVNELLDLARMEAGYIDLNLEEVDLDSYLERITRKFASFAREYDVTVELAKPGRGQIAV
HHHHHHHHHHHHCCCEEEECHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEE
FDPDRIEQVLTNLIHNAIRHTNPGGLITVVHEQEEERDTFAVVDTGRGIPEEDLPYVFER
ECHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHH
FYKADKARTRQHGGTGLGLAIAKHIIDAHQGKITVHSRLGEGTTFHFTLPKQQGDKGK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MMLWQSVVGKLWFTILLLVTAVLTILMVLLLRFTEGNAIEEAESRLNSYANMAKTMYETH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
TDETSTYDYLQSLSNEFQINITIIKNGAKAWSAQGNRSGEINVATLLEEWSVEGLEKGER
CCCCHHHHHHHHCCCCEEEEEEEEECCCHHHCCCCCCCCCCHHHHHHHHHCHHHHHCCCE
IVTEANYPASGQEQDPIEMIVVGVPLSEDYLTSSGIILYQPLSAVEEAAAETRRIIYLSA
EEEECCCCCCCCCCCCEEEEEEECCCCCCHHCCCCEEEECCHHHHHHHHHHHCEEEEEEC
GIALVLTTVFAFFLSSRITAPLRKMRQAALEVAQGQFHTKVPILTQDEIGQLAIAFNRMR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHH
RELNRNISELNQEKEQLSHILASMADGVITLDRQGRILLTNPQAEEVLALLFYEEGQKPI
HHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCC
TGERKTLPVSLTPLFEQVVSAEKEELQELSVQGRSMAVLMAPLYAEEHVRGAVAVVRDVT
CCCCCEECEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
EERRHDKLRKDFIANVSHELRTPISMLQGYSEAMVDGVTSSDEERKEVAQIIYDESLRMG
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
RLVNELLDLARMEAGYIDLNLEEVDLDSYLERITRKFASFAREYDVTVELAKPGRGQIAV
HHHHHHHHHHHHCCCEEEECHHHCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEE
FDPDRIEQVLTNLIHNAIRHTNPGGLITVVHEQEEERDTFAVVDTGRGIPEEDLPYVFER
ECHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHH
FYKADKARTRQHGGTGLGLAIAKHIIDAHQGKITVHSRLGEGTTFHFTLPKQQGDKGK
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]