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The map label for this gene is resD [H]

Identifier: 56963600

GI number: 56963600

Start: 1952073

End: 1952789

Strand: Direct

Name: resD [H]

Synonym: ABC1835

Alternate gene names: 56963600

Gene position: 1952073-1952789 (Clockwise)

Preceding gene: 56963599

Following gene: 56963601

Centisome position: 45.36

GC content: 46.3

Gene sequence:

>717_bases
ATGGAATACAAGCCAACATTGCTTGTTGTTGATGATGAAGAGCGGATTCGCCGCCTATTGCGAATGTATTTAGAAAGGGA
AGAGTACCAAATTGAAGAAGCAAGCAATGGCGAGGAGGCACTTGAACTCGCCCTTGCCAAAGAATATGACTTGATTTTGC
TTGATGTGATGATGCCTGGGATGGACGGCGTCGAGATGTGCCAAGAGCTCCGTAAGAAAAAAGCGACGCCTGTAATGATG
TTGACGGCCAAGGGAGAAGAAGCAAACCGTGTGCAAGGGTTTGAAGTAGGAGCCGACGATTACATTGTCAAACCGTTCAG
CCCCCGGGAAGTGGTGCTCCGTGTGAAAGCTTTGTTGCGCCGTGCATCTGCTACTAAGTTTTTGCAAACTGACACACAGA
CAAAAGATGTGCTCGTGTTTGGGCCACTCACGATTGACAATGATGCCCATCGAGTGACTGTTGACAAGACGGAAATTAGT
TTGACGCCAAAAGAATATGAACTGCTCTTTTATTTGGCGCAATCACCAGATAAAGTGTTTTCTCGTGAACAGCTATTAAA
GGATGTTTGGAACTATGAGTTTTTTGGCGACTTGCGAACAGTCGATACACATGTCAAACGGTTACGCGAAAAATTGAATC
GCGTTTCTCCAGAAGTAGCAGCCATTATTTCAACCGTTTGGGGGGTTGGATACAAGTTTGAGGCGACGCGTGGGTGA

Upstream 100 bases:

>100_bases
TGCTGGAACAATTCCGCATTTTTAGTCGTACGAATGGCAACTAAAATTTCTTCCGTGGTACACTACTAAGGAGAGCAGTA
TCGATAAGGAGGTTTCCCAA

Downstream 100 bases:

>100_bases
TGCTGTGGCAAAGTGTAGTCGGGAAATTATGGTTTACCATCCTTTTGCTTGTCACAGCTGTATTGACAATTCTAATGGTG
CTGCTGCTTCGCTTTACAGA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MEYKPTLLVVDDEERIRRLLRMYLEREEYQIEEASNGEEALELALAKEYDLILLDVMMPGMDGVEMCQELRKKKATPVMM
LTAKGEEANRVQGFEVGADDYIVKPFSPREVVLRVKALLRRASATKFLQTDTQTKDVLVFGPLTIDNDAHRVTVDKTEIS
LTPKEYELLFYLAQSPDKVFSREQLLKDVWNYEFFGDLRTVDTHVKRLREKLNRVSPEVAAIISTVWGVGYKFEATRG

Sequences:

>Translated_238_residues
MEYKPTLLVVDDEERIRRLLRMYLEREEYQIEEASNGEEALELALAKEYDLILLDVMMPGMDGVEMCQELRKKKATPVMM
LTAKGEEANRVQGFEVGADDYIVKPFSPREVVLRVKALLRRASATKFLQTDTQTKDVLVFGPLTIDNDAHRVTVDKTEIS
LTPKEYELLFYLAQSPDKVFSREQLLKDVWNYEFFGDLRTVDTHVKRLREKLNRVSPEVAAIISTVWGVGYKFEATRG
>Mature_238_residues
MEYKPTLLVVDDEERIRRLLRMYLEREEYQIEEASNGEEALELALAKEYDLILLDVMMPGMDGVEMCQELRKKKATPVMM
LTAKGEEANRVQGFEVGADDYIVKPFSPREVVLRVKALLRRASATKFLQTDTQTKDVLVFGPLTIDNDAHRVTVDKTEIS
LTPKEYELLFYLAQSPDKVFSREQLLKDVWNYEFFGDLRTVDTHVKRLREKLNRVSPEVAAIISTVWGVGYKFEATRG

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=42.9787234042553, Blast_Score=180, Evalue=6e-47,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=40, Blast_Score=170, Evalue=8e-44,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=37.6623376623377, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=36.4035087719298, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1786784, Length=234, Percent_Identity=37.6068376068376, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=38.5281385281385, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=31.304347826087, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=34.6491228070175, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=36.3247863247863, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI2367329, Length=206, Percent_Identity=37.8640776699029, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=32.6086956521739, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=32.9004329004329, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=31.140350877193, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=28.3842794759825, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788550, Length=164, Percent_Identity=32.3170731707317, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790299, Length=137, Percent_Identity=34.3065693430657, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788191, Length=105, Percent_Identity=37.1428571428571, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787473, Length=181, Percent_Identity=31.4917127071823, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=34.2857142857143, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789149, Length=188, Percent_Identity=29.7872340425532, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788521, Length=222, Percent_Identity=30.1801801801802, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=101, Percent_Identity=34.6534653465347, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788222, Length=129, Percent_Identity=29.4573643410853, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27473; Mature: 27473

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYKPTLLVVDDEERIRRLLRMYLEREEYQIEEASNGEEALELALAKEYDLILLDVMMPG
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCC
MDGVEMCQELRKKKATPVMMLTAKGEEANRVQGFEVGADDYIVKPFSPREVVLRVKALLR
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCCEEECCCCHHHHHHHHHHHHH
RASATKFLQTDTQTKDVLVFGPLTIDNDAHRVTVDKTEISLTPKEYELLFYLAQSPDKVF
HHHHHHHHHCCCCCCCEEEEECEEECCCCCEEEEECCEEEECCCCEEEEEEEECCCHHHH
SREQLLKDVWNYEFFGDLRTVDTHVKRLREKLNRVSPEVAAIISTVWGVGYKFEATRG
HHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCC
>Mature Secondary Structure
MEYKPTLLVVDDEERIRRLLRMYLEREEYQIEEASNGEEALELALAKEYDLILLDVMMPG
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEECCCC
MDGVEMCQELRKKKATPVMMLTAKGEEANRVQGFEVGADDYIVKPFSPREVVLRVKALLR
CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCCEEECCCCHHHHHHHHHHHHH
RASATKFLQTDTQTKDVLVFGPLTIDNDAHRVTVDKTEISLTPKEYELLFYLAQSPDKVF
HHHHHHHHHCCCCCCCEEEEECEEECCCCCEEEEECCEEEECCCCEEEEEEEECCCHHHH
SREQLLKDVWNYEFFGDLRTVDTHVKRLREKLNRVSPEVAAIISTVWGVGYKFEATRG
HHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]