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The map label for this gene is ribH

Identifier: 56963578

GI number: 56963578

Start: 1932507

End: 1932977

Strand: Direct

Name: ribH

Synonym: ABC1813

Alternate gene names: 56963578

Gene position: 1932507-1932977 (Clockwise)

Preceding gene: 56963577

Following gene: 56963580

Centisome position: 44.9

GC content: 46.92

Gene sequence:

>471_bases
ATGGGGAAAAATTATGAAGGCCATTTGGTGGCATCTGGATTAAAGGTTGGAATTGTTGTGGGTCGTTTCAATGAATTTAT
TACAAGCAAACTTCTCGGCGGCGCTCAAGATGGGTTAATCCGCCATGGAGCAGATGAAGGCGATATCGATGTGGCTTGGG
TTCCAGGAGCGTTCGAGATCCCGTTTGCAGCCAAAAAAATGGCTGAAAGCGGCCGATACGATGCGGTCATCACTTTAGGG
ACTGTCATACGAGGGTCGACGCCTCATTTTGACTACGTTTGTAATGAAGTGGCGAAAGGCGTCTCTTCATTGGCATTAAC
AACTGGGATTCCCGTCATTTTTGGTGTCTTAACAACGGATACAATCGAACAAGCTGTTGAACGAGCAGGCACAAAAGCAG
GAAACAAAGGATGGGAAGCAGCAAGCGCGGCGATTGAAATGGCGAATCTAGCAAAGCAGTTTGAGGAATAA

Upstream 100 bases:

>100_bases
GTGTGCCACTGCAAATGGAAGCTGTAGCCGAAAATGAACGTTATTTGCATACGAAAAGAGAAAAACTTGGGCATATGCTC
AATTTATAGGAGGGCTTTAA

Downstream 100 bases:

>100_bases
CAGCTAGCATTTTCTATCAGTCTGAGTGATTTTGTCGACAACTCAAACGGCCCTGAAGGGGCCGTTTTTTTCTGCTGTTT
TACTTCCTTATTGGCCATTT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MGKNYEGHLVASGLKVGIVVGRFNEFITSKLLGGAQDGLIRHGADEGDIDVAWVPGAFEIPFAAKKMAESGRYDAVITLG
TVIRGSTPHFDYVCNEVAKGVSSLALTTGIPVIFGVLTTDTIEQAVERAGTKAGNKGWEAASAAIEMANLAKQFEE

Sequences:

>Translated_156_residues
MGKNYEGHLVASGLKVGIVVGRFNEFITSKLLGGAQDGLIRHGADEGDIDVAWVPGAFEIPFAAKKMAESGRYDAVITLG
TVIRGSTPHFDYVCNEVAKGVSSLALTTGIPVIFGVLTTDTIEQAVERAGTKAGNKGWEAASAAIEMANLAKQFEE
>Mature_155_residues
GKNYEGHLVASGLKVGIVVGRFNEFITSKLLGGAQDGLIRHGADEGDIDVAWVPGAFEIPFAAKKMAESGRYDAVITLGT
VIRGSTPHFDYVCNEVAKGVSSLALTTGIPVIFGVLTTDTIEQAVERAGTKAGNKGWEAASAAIEMANLAKQFEE

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=151, Percent_Identity=52.9801324503311, Blast_Score=156, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6324429, Length=146, Percent_Identity=36.986301369863, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_BACSK (Q5WH07)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175309.1
- HSSP:   P11998
- ProteinModelPortal:   Q5WH07
- SMR:   Q5WH07
- STRING:   Q5WH07
- EnsemblBacteria:   EBBACT00000047043
- GeneID:   3201513
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1813
- NMPDR:   fig|66692.3.peg.1761
- eggNOG:   COG0054
- GeneTree:   EBGT00050000002577
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- ProtClustDB:   PRK00061
- BioCyc:   BCLA66692:ABC1813-MONOMER
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16399; Mature: 16268

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKNYEGHLVASGLKVGIVVGRFNEFITSKLLGGAQDGLIRHGADEGDIDVAWVPGAFEI
CCCCCCCEEEECCCEEEEEEHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEECCCCCCC
PFAAKKMAESGRYDAVITLGTVIRGSTPHFDYVCNEVAKGVSSLALTTGIPVIFGVLTTD
CHHHHHHHHCCCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
TIEQAVERAGTKAGNKGWEAASAAIEMANLAKQFEE
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GKNYEGHLVASGLKVGIVVGRFNEFITSKLLGGAQDGLIRHGADEGDIDVAWVPGAFEI
CCCCCCEEEECCCEEEEEEHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEECCCCCCC
PFAAKKMAESGRYDAVITLGTVIRGSTPHFDYVCNEVAKGVSSLALTTGIPVIFGVLTTD
CHHHHHHHHCCCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
TIEQAVERAGTKAGNKGWEAASAAIEMANLAKQFEE
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA