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The map label for this gene is pbpA [H]

Identifier: 56963482

GI number: 56963482

Start: 1844929

End: 1847031

Strand: Direct

Name: pbpA [H]

Synonym: ABC1717

Alternate gene names: 56963482

Gene position: 1844929-1847031 (Clockwise)

Preceding gene: 56963481

Following gene: 56963485

Centisome position: 42.87

GC content: 46.55

Gene sequence:

>2103_bases
ATGGCTGAGAAAAAAAACAAAGCGCGCAGCCAAGTATCCGCCAGGCTAAATATTTTGTTTCTTGGCGTGTTTTTGTTGTT
TTCTGCATTGATTTTGCGTCTCGGCATGGTCCAAATAGTCCAAGGCGAATCTTACGAAGAAGAGTTAACACATGTATCGA
ACCAAACGGCCCGCATCGACGCGCCCCGTGGACTGATGTATGATAGCTACGGCAATGTGGTGGTCGACAATTCCATGGAG
TTGTCTGTCACTTACACCAATCCTGGGAACCAAAAAGCCGAAGATATTCTTGAATTAGCGATAAAGCTGTCTGATTTCAT
TGAAGTCGACACAGAGAATCTCCGTTTTCGCGACAAACAAGAATATTGGTATGTCACTCATAGCGAAAAAGAGCGGAAGG
CGTTAATCGAAGGAAAAAAAGTCGACGATAAAGACGAGTACCAAACGATTATAGATGAAATTACAGAAGAGATGGTCGAT
GGCTATTCGAAAGAAGAAGAACAAGTCATTGCAATTTTTACACATATGCTCCGCGGTACTAGCGGCACGCCACAACGAAT
TAAACAATCGATTACGGAAGAGGAAGCCCATGTGTTAAGTGAGCACTTGGACAAGCTGCCGAACATCGACTTGCAGCGGG
ATGCGACAAGGGAGTACGTATATGGCGACACGTTGCGGCAATTGTATGGCAGCGTTGGGTCAATCCAATCGGAAAAAGTC
GATGATTATTTGGCAAACGGCTATGCCCGCTCTGATCTTGTCGGCAACAGCTATTTGGAGCTTCAATATGAAAATGTGCT
CCGTGGCACAAAAGCGGAAATTTCGCGGACATCCACACGGACTGGCGGCGAGGAAGCCGAAAGCGTCGTCGAAGAAACAC
TTGGCAGCCGTGGCAATGACTTAGTATTAAGCGTTGATATGGAGTACCAACAACTGCTTGATGAAGCGGTAGAAAAACAT
GTCATGAAAAACCGCGGCTACTACTTGCAGCAGCAAGAAGGCAGCGCCTATGCGATTGTGATGAATCCAAAAACAGGTGA
AATATTAGCGATTAGCGGTTTTGTCGATCCTGCCGGAGAAGATGAAAGCTATTTGCACCCAACCGGAGCTGTGAACAATG
CGTTTGAGTTTGGCTCTGTCGTCAAAGGGGCATCCGTGTTAACCGGCATGCAAGAGGGCGTTGTCACTCCTGATACGGTT
GTTAATGACCAGCCGTTGCATTTTAATGGCACGCCTGAGAAAAAATCCGTTACATCAATGGGGCCTGTTAATATGGGTAC
TGCGTTAGAACGGTCTTCGAACGTCTATATGTTTGAAATTGCGATGCGAATGGGCAACTATACGTACAACAGCAACATCC
CCCAAAGCCAACGTAGCTTGTTTGGCCTGTCCGTCGCCAATGATGTGTTAGAGCGTTCACGTTATTATTTCAGCCAATTT
GGCTTAGGGACTCAAACGGGAATTGACCTTCCCCATGAAGTAACAGGTATTACCGGCGTTCCACAAGAGCCAGGGGCTTC
ACTTGACTTTATGATCGGCCAATTCGACACTTATACGACGTTGCAGGTTGGCCAGTACGCGAGCACGATTGCCAATGATG
GCGTGCGCATGCGCCCTCGTCTTGTCAAAGAAATATTGGAGCCTTCTATCAATGGAGAAGAAGCGACCGTTGTAAAGGAA
TTTGCGCCTGAAGTGCTTAATGAAGTCGACATGTCTAAAGACAAACTTGACGTGGTGCAAAATGGCTTCCGCCGCGTGGT
GACAGGCAGCCGCGGTACAGCTAGCTCAATTAAAACGGATGTGCCAATTGCTGCTAAGACTGGGACAGCTGAGATTTCCG
TGGCGATTGGCGAAGGCGATAATCGCCAAGTTTTAAACGGAAACAACCAAAGCTTTATTGGCTATGCTCCCTATGACGAT
CCAGAGATTGCCTTTGCTGTCATCGCTCCAAAAGTGCAAATTCCAAGGGGAACATCGTATAAAATTGCTCAAGGCATTGC
CCAAGACTTAGTCAATGACTACTTTGATTTACAGGAAAACCGAGAGGGCCCTAAATCAGTCGATTCAGTCATGGATGAAG
TTGATTTGTTTGAAAATGAGTAA

Upstream 100 bases:

>100_bases
CGGGTAAAGAGTAGAAAAGGCATCCGCTTGCCGGGTGTCTTTTTGTGTTGGGAATTTATAAGCTGTTAGGCGATACATAA
ATGATGATGGAGGGGAAATG

Downstream 100 bases:

>100_bases
ATAAAAATCCAGCGAGCAGATAAAGCTCGCTGGATTTTTATACTAGAAAAACACTTACTCGATTTTCAGTTAGAAAGGTT
GCCGACAAAATCGGCAACCT

Product: penicillin-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MAEKKNKARSQVSARLNILFLGVFLLFSALILRLGMVQIVQGESYEEELTHVSNQTARIDAPRGLMYDSYGNVVVDNSME
LSVTYTNPGNQKAEDILELAIKLSDFIEVDTENLRFRDKQEYWYVTHSEKERKALIEGKKVDDKDEYQTIIDEITEEMVD
GYSKEEEQVIAIFTHMLRGTSGTPQRIKQSITEEEAHVLSEHLDKLPNIDLQRDATREYVYGDTLRQLYGSVGSIQSEKV
DDYLANGYARSDLVGNSYLELQYENVLRGTKAEISRTSTRTGGEEAESVVEETLGSRGNDLVLSVDMEYQQLLDEAVEKH
VMKNRGYYLQQQEGSAYAIVMNPKTGEILAISGFVDPAGEDESYLHPTGAVNNAFEFGSVVKGASVLTGMQEGVVTPDTV
VNDQPLHFNGTPEKKSVTSMGPVNMGTALERSSNVYMFEIAMRMGNYTYNSNIPQSQRSLFGLSVANDVLERSRYYFSQF
GLGTQTGIDLPHEVTGITGVPQEPGASLDFMIGQFDTYTTLQVGQYASTIANDGVRMRPRLVKEILEPSINGEEATVVKE
FAPEVLNEVDMSKDKLDVVQNGFRRVVTGSRGTASSIKTDVPIAAKTGTAEISVAIGEGDNRQVLNGNNQSFIGYAPYDD
PEIAFAVIAPKVQIPRGTSYKIAQGIAQDLVNDYFDLQENREGPKSVDSVMDEVDLFENE

Sequences:

>Translated_700_residues
MAEKKNKARSQVSARLNILFLGVFLLFSALILRLGMVQIVQGESYEEELTHVSNQTARIDAPRGLMYDSYGNVVVDNSME
LSVTYTNPGNQKAEDILELAIKLSDFIEVDTENLRFRDKQEYWYVTHSEKERKALIEGKKVDDKDEYQTIIDEITEEMVD
GYSKEEEQVIAIFTHMLRGTSGTPQRIKQSITEEEAHVLSEHLDKLPNIDLQRDATREYVYGDTLRQLYGSVGSIQSEKV
DDYLANGYARSDLVGNSYLELQYENVLRGTKAEISRTSTRTGGEEAESVVEETLGSRGNDLVLSVDMEYQQLLDEAVEKH
VMKNRGYYLQQQEGSAYAIVMNPKTGEILAISGFVDPAGEDESYLHPTGAVNNAFEFGSVVKGASVLTGMQEGVVTPDTV
VNDQPLHFNGTPEKKSVTSMGPVNMGTALERSSNVYMFEIAMRMGNYTYNSNIPQSQRSLFGLSVANDVLERSRYYFSQF
GLGTQTGIDLPHEVTGITGVPQEPGASLDFMIGQFDTYTTLQVGQYASTIANDGVRMRPRLVKEILEPSINGEEATVVKE
FAPEVLNEVDMSKDKLDVVQNGFRRVVTGSRGTASSIKTDVPIAAKTGTAEISVAIGEGDNRQVLNGNNQSFIGYAPYDD
PEIAFAVIAPKVQIPRGTSYKIAQGIAQDLVNDYFDLQENREGPKSVDSVMDEVDLFENE
>Mature_699_residues
AEKKNKARSQVSARLNILFLGVFLLFSALILRLGMVQIVQGESYEEELTHVSNQTARIDAPRGLMYDSYGNVVVDNSMEL
SVTYTNPGNQKAEDILELAIKLSDFIEVDTENLRFRDKQEYWYVTHSEKERKALIEGKKVDDKDEYQTIIDEITEEMVDG
YSKEEEQVIAIFTHMLRGTSGTPQRIKQSITEEEAHVLSEHLDKLPNIDLQRDATREYVYGDTLRQLYGSVGSIQSEKVD
DYLANGYARSDLVGNSYLELQYENVLRGTKAEISRTSTRTGGEEAESVVEETLGSRGNDLVLSVDMEYQQLLDEAVEKHV
MKNRGYYLQQQEGSAYAIVMNPKTGEILAISGFVDPAGEDESYLHPTGAVNNAFEFGSVVKGASVLTGMQEGVVTPDTVV
NDQPLHFNGTPEKKSVTSMGPVNMGTALERSSNVYMFEIAMRMGNYTYNSNIPQSQRSLFGLSVANDVLERSRYYFSQFG
LGTQTGIDLPHEVTGITGVPQEPGASLDFMIGQFDTYTTLQVGQYASTIANDGVRMRPRLVKEILEPSINGEEATVVKEF
APEVLNEVDMSKDKLDVVQNGFRRVVTGSRGTASSIKTDVPIAAKTGTAEISVAIGEGDNRQVLNGNNQSFIGYAPYDDP
EIAFAVIAPKVQIPRGTSYKIAQGIAQDLVNDYFDLQENREGPKSVDSVMDEVDLFENE

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=456, Percent_Identity=25.4385964912281, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 77673; Mature: 77541

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKNKARSQVSARLNILFLGVFLLFSALILRLGMVQIVQGESYEEELTHVSNQTARID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEC
APRGLMYDSYGNVVVDNSMELSVTYTNPGNQKAEDILELAIKLSDFIEVDTENLRFRDKQ
CCCCCEEECCCCEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCCCCEECCC
EYWYVTHSEKERKALIEGKKVDDKDEYQTIIDEITEEMVDGYSKEEEQVIAIFTHMLRGT
CEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
SGTPQRIKQSITEEEAHVLSEHLDKLPNIDLQRDATREYVYGDTLRQLYGSVGSIQSEKV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
DDYLANGYARSDLVGNSYLELQYENVLRGTKAEISRTSTRTGGEEAESVVEETLGSRGND
HHHHHCCCHHHCCCCCCEEEEEHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCE
LVLSVDMEYQQLLDEAVEKHVMKNRGYYLQQQEGSAYAIVMNPKTGEILAISGFVDPAGE
EEEEECHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCEEEEECCCCCCCC
DESYLHPTGAVNNAFEFGSVVKGASVLTGMQEGVVTPDTVVNDQPLHFNGTPEKKSVTSM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCC
GPVNMGTALERSSNVYMFEIAMRMGNYTYNSNIPQSQRSLFGLSVANDVLERSRYYFSQF
CCCCCCHHHHCCCCEEEEEEEHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GLGTQTGIDLPHEVTGITGVPQEPGASLDFMIGQFDTYTTLQVGQYASTIANDGVRMRPR
CCCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHCCCCEECHH
LVKEILEPSINGEEATVVKEFAPEVLNEVDMSKDKLDVVQNGFRRVVTGSRGTASSIKTD
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
VPIAAKTGTAEISVAIGEGDNRQVLNGNNQSFIGYAPYDDPEIAFAVIAPKVQIPRGTSY
CCEEECCCCEEEEEEECCCCCCEEECCCCCCEEEECCCCCCCEEEEEEECEEECCCCCCH
KIAQGIAQDLVNDYFDLQENREGPKSVDSVMDEVDLFENE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEKKNKARSQVSARLNILFLGVFLLFSALILRLGMVQIVQGESYEEELTHVSNQTARID
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEC
APRGLMYDSYGNVVVDNSMELSVTYTNPGNQKAEDILELAIKLSDFIEVDTENLRFRDKQ
CCCCCEEECCCCEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCCCCEECCC
EYWYVTHSEKERKALIEGKKVDDKDEYQTIIDEITEEMVDGYSKEEEQVIAIFTHMLRGT
CEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
SGTPQRIKQSITEEEAHVLSEHLDKLPNIDLQRDATREYVYGDTLRQLYGSVGSIQSEKV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
DDYLANGYARSDLVGNSYLELQYENVLRGTKAEISRTSTRTGGEEAESVVEETLGSRGND
HHHHHCCCHHHCCCCCCEEEEEHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCE
LVLSVDMEYQQLLDEAVEKHVMKNRGYYLQQQEGSAYAIVMNPKTGEILAISGFVDPAGE
EEEEECHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCEEEEECCCCCCCC
DESYLHPTGAVNNAFEFGSVVKGASVLTGMQEGVVTPDTVVNDQPLHFNGTPEKKSVTSM
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCC
GPVNMGTALERSSNVYMFEIAMRMGNYTYNSNIPQSQRSLFGLSVANDVLERSRYYFSQF
CCCCCCHHHHCCCCEEEEEEEHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
GLGTQTGIDLPHEVTGITGVPQEPGASLDFMIGQFDTYTTLQVGQYASTIANDGVRMRPR
CCCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEECCCCEEEEEHHHHHHHHHCCCCEECHH
LVKEILEPSINGEEATVVKEFAPEVLNEVDMSKDKLDVVQNGFRRVVTGSRGTASSIKTD
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
VPIAAKTGTAEISVAIGEGDNRQVLNGNNQSFIGYAPYDDPEIAFAVIAPKVQIPRGTSY
CCEEECCCCEEEEEEECCCCCCEEECCCCCCEEEECCCCCCCEEEEEEECEEECCCCCCH
KIAQGIAQDLVNDYFDLQENREGPKSVDSVMDEVDLFENE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]