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The map label for this gene is cdd [H]

Identifier: 56963445

GI number: 56963445

Start: 1809272

End: 1809688

Strand: Direct

Name: cdd [H]

Synonym: ABC1680

Alternate gene names: 56963445

Gene position: 1809272-1809688 (Clockwise)

Preceding gene: 56963444

Following gene: 56963446

Centisome position: 42.04

GC content: 45.08

Gene sequence:

>417_bases
ATGGATGCCGAAACATTAATGCAACATGCGATCACAGCAAGGAAGGACGCCTACGTCCCTTATTCATCGTTCGCTGTAGG
AGCGGCTTTGCTCCTTGAAGACGGTTCAGTTGTCTTAGGGGGAAATATTGAAAATGCAGCATATAGCTTAGCGAATTGCG
CTGAGCGGACTGCTTTGTTTAAAGCATATCGAGCGGGGCAAAAGCCATTTAAAGCAATGGCAGTTGCAGCAGACACTCCA
GGACCAGTCTCGCCGTGCGGTGCATGCAGGCAAGTGCTGGCCGAATTGTGTCCACCAGAAATGCCTGTGTATTTATGTAA
CTTAAAAGGAAATGTGAAACAAACAACAGTGGAAGAATTGCTGCCTGGATTTTTTAAAGCGGAGGATTTATATGAAGCAA
AAAACAACAACATTTAA

Upstream 100 bases:

>100_bases
CAGTGTGTTCGTGTTCTGTATCTTTGCTGCGGTAATAGGAGTGATGATCTTTTTTCCGTACTTGCTCGAATTATTCCAGT
AAGAAGGAGTCGGTGCTAAA

Downstream 100 bases:

>100_bases
ATCAGGGTTTGTGTCCATTATTGGCAGGCCAAATGTTGGAAAGTCAACCCTTTTAAACCGGGTGATTGGCCAGAAAATTG
CCATTATGTCAGACAAGCCG

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MDAETLMQHAITARKDAYVPYSSFAVGAALLLEDGSVVLGGNIENAAYSLANCAERTALFKAYRAGQKPFKAMAVAADTP
GPVSPCGACRQVLAELCPPEMPVYLCNLKGNVKQTTVEELLPGFFKAEDLYEAKNNNI

Sequences:

>Translated_138_residues
MDAETLMQHAITARKDAYVPYSSFAVGAALLLEDGSVVLGGNIENAAYSLANCAERTALFKAYRAGQKPFKAMAVAADTP
GPVSPCGACRQVLAELCPPEMPVYLCNLKGNVKQTTVEELLPGFFKAEDLYEAKNNNI
>Mature_138_residues
MDAETLMQHAITARKDAYVPYSSFAVGAALLLEDGSVVLGGNIENAAYSLANCAERTALFKAYRAGQKPFKAMAVAADTP
GPVSPCGACRQVLAELCPPEMPVYLCNLKGNVKQTTVEELLPGFFKAEDLYEAKNNNI

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=132, Percent_Identity=47.7272727272727, Blast_Score=113, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17551074, Length=127, Percent_Identity=40.9448818897638, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540514, Length=125, Percent_Identity=42.4, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323274, Length=130, Percent_Identity=37.6923076923077, Blast_Score=87, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24582741, Length=127, Percent_Identity=46.4566929133858, Blast_Score=96, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24582744, Length=105, Percent_Identity=44.7619047619048, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI19920920, Length=104, Percent_Identity=44.2307692307692, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14761; Mature: 14761

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAETLMQHAITARKDAYVPYSSFAVGAALLLEDGSVVLGGNIENAAYSLANCAERTALF
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHEECCCCEEECCCCCHHHHHHHHHHHHHHHH
KAYRAGQKPFKAMAVAADTPGPVSPCGACRQVLAELCPPEMPVYLCNLKGNVKQTTVEEL
HHHHCCCCCHHHEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHH
LPGFFKAEDLYEAKNNNI
CCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDAETLMQHAITARKDAYVPYSSFAVGAALLLEDGSVVLGGNIENAAYSLANCAERTALF
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHEECCCCEEECCCCCHHHHHHHHHHHHHHHH
KAYRAGQKPFKAMAVAADTPGPVSPCGACRQVLAELCPPEMPVYLCNLKGNVKQTTVEEL
HHHHCCCCCHHHEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHH
LPGFFKAEDLYEAKNNNI
CCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]