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The map label for this gene is dra

Identifier: 56963431

GI number: 56963431

Start: 1796909

End: 1797583

Strand: Direct

Name: dra

Synonym: ABC1666

Alternate gene names: 56963431

Gene position: 1796909-1797583 (Clockwise)

Preceding gene: 56963429

Following gene: 56963434

Centisome position: 41.75

GC content: 45.78

Gene sequence:

>675_bases
ATGGCAACCGATATCGCAAGGTTGATTGACCATACACTGCTTAAGGCAGATGCGACAAAGGAACAAATTCTCCAATTATG
TAAAGAAGCACAAACATACCAATTTGCCTCAGTCTGCATTAACCCCTATTGGGTAAAACTCGCCGCTGAACAATTGAAAG
AGGACAAACATGTTGCAGTTTGTACAGTAATTGGCTTTCCTCTAGGCCAATCAACGCCTGAAACGAAAGCGTTTGAAACA
AAAAACGCGATTGCCAATGGCGCCACTGAAGTCGATATGGTTATCAATATTGCGGCTCTTAAAGATAAACAAGACCAAAT
GGTGTTAAATGATATTCGAGCGGTTGTCGATGCTGCAAAAGATAAAGCACTGACAAAAGTCATTCTCGAAACATGCTTGT
TGACGAACGAAGAAAAAGAGCGTGCATGTGCACTTGCTGTTCAAGCAGGAGCCGATTATGTCAAAACGTCTACAGGCTTC
TCAACAGGAGGAGCTACGGTGGAAGATATTGCGTTAATGCGCCGAGTTGTCGGTGCGGATGTCGGTGTGAAAGCTTCCGG
GGGTATTCGTGATTTAGCAGCTGTGAATGCGATGGTAGAAGCAGGCGCCACTCGTATTGGCGCAAGTGCAGGGGTAGCGA
TCGTAACAGGTGCCACAGGAAGTAGCGGCTACTAA

Upstream 100 bases:

>100_bases
AAAACGACAATCGCCAATTGCTCGTCTAGTTGGCTGTTCGTTTTGTCTTTTTTCATGGTATGATAGCTAGGCACGTACAA
ATCAGGAAAGGGTGGGTTCA

Downstream 100 bases:

>100_bases
TACACAAAGGCGCTAAGTGCTCTAACGGATATGCCTGTCCAATGATGAAGTATACGAGCATTTGTCTACAGTCTGAAAGG
CGGAGAGATACTCCGCCTTT

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MATDIARLIDHTLLKADATKEQILQLCKEAQTYQFASVCINPYWVKLAAEQLKEDKHVAVCTVIGFPLGQSTPETKAFET
KNAIANGATEVDMVINIAALKDKQDQMVLNDIRAVVDAAKDKALTKVILETCLLTNEEKERACALAVQAGADYVKTSTGF
STGGATVEDIALMRRVVGADVGVKASGGIRDLAAVNAMVEAGATRIGASAGVAIVTGATGSSGY

Sequences:

>Translated_224_residues
MATDIARLIDHTLLKADATKEQILQLCKEAQTYQFASVCINPYWVKLAAEQLKEDKHVAVCTVIGFPLGQSTPETKAFET
KNAIANGATEVDMVINIAALKDKQDQMVLNDIRAVVDAAKDKALTKVILETCLLTNEEKERACALAVQAGADYVKTSTGF
STGGATVEDIALMRRVVGADVGVKASGGIRDLAAVNAMVEAGATRIGASAGVAIVTGATGSSGY
>Mature_223_residues
ATDIARLIDHTLLKADATKEQILQLCKEAQTYQFASVCINPYWVKLAAEQLKEDKHVAVCTVIGFPLGQSTPETKAFETK
NAIANGATEVDMVINIAALKDKQDQMVLNDIRAVVDAAKDKALTKVILETCLLTNEEKERACALAVQAGADYVKTSTGFS
TGGATVEDIALMRRVVGADVGVKASGGIRDLAAVNAMVEAGATRIGASAGVAIVTGATGSSGY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=212, Percent_Identity=33.9622641509434, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1790841, Length=195, Percent_Identity=35.8974358974359, Blast_Score=94, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17533015, Length=202, Percent_Identity=29.7029702970297, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922098, Length=216, Percent_Identity=32.4074074074074, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_BACSK (Q5WHF4)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175162.1
- ProteinModelPortal:   Q5WHF4
- SMR:   Q5WHF4
- STRING:   Q5WHF4
- EnsemblBacteria:   EBBACT00000049449
- GeneID:   3202335
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1666
- NMPDR:   fig|66692.3.peg.49
- eggNOG:   COG0274
- GeneTree:   EBGT00050000000908
- HOGENOM:   HBG636421
- OMA:   GANTPEV
- BioCyc:   BCLA66692:ABC1666-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23475; Mature: 23344

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: ACT_SITE 155-155 ACT_SITE 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDIARLIDHTLLKADATKEQILQLCKEAQTYQFASVCINPYWVKLAAEQLKEDKHVAV
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEE
CTVIGFPLGQSTPETKAFETKNAIANGATEVDMVINIAALKDKQDQMVLNDIRAVVDAAK
EEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHEEHHHHCCCHHHHHHHHHHHHHHHHH
DKALTKVILETCLLTNEEKERACALAVQAGADYVKTSTGFSTGGATVEDIALMRRVVGAD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCC
VGVKASGGIRDLAAVNAMVEAGATRIGASAGVAIVTGATGSSGY
CCCCCCCCHHHHHHHHHHHHHCCHHCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
ATDIARLIDHTLLKADATKEQILQLCKEAQTYQFASVCINPYWVKLAAEQLKEDKHVAV
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEE
CTVIGFPLGQSTPETKAFETKNAIANGATEVDMVINIAALKDKQDQMVLNDIRAVVDAAK
EEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHEEHHHHCCCHHHHHHHHHHHHHHHHH
DKALTKVILETCLLTNEEKERACALAVQAGADYVKTSTGFSTGGATVEDIALMRRVVGAD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCC
VGVKASGGIRDLAAVNAMVEAGATRIGASAGVAIVTGATGSSGY
CCCCCCCCHHHHHHHHHHHHHCCHHCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA