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The map label for this gene is holA [H]

Identifier: 56963415

GI number: 56963415

Start: 1778796

End: 1779818

Strand: Direct

Name: holA [H]

Synonym: ABC1650

Alternate gene names: 56963415

Gene position: 1778796-1779818 (Clockwise)

Preceding gene: 56963413

Following gene: 56963417

Centisome position: 41.33

GC content: 46.43

Gene sequence:

>1023_bases
ATGAGCATCATTACGGAAATGAAGCAATTGTCGAGTGAGACAATGGCACCGGTATACTTTTTGTATGGGACAGAACGTTA
TTTAATCGAGCAATTTTTACAAAAAGCAAGCGAAGCATTATTTGCAGGGGAAGAAGGCGAAATGAATGATATTCGCTTAC
GCTTACAAGATACGCCGCTAGGGGAAGTGGTGGAGGAAGCGGAGACTGTTCCGTTTTTCTCAAAGCGGAAACTTGTTGTG
ATCCAAGACTTTTATTTGGCAACGAGCCAGAAAGTAGCGACAAAACTGGAGCATGACATTCCCGCACTGGAAGCCTATCT
CGACTCGCCTGCACAAGAAACCGTGCTTGTCGTTGTCGCGCCGTATGAAAAATTAGATGAACGCAAGAAAATCACCAAAA
AATTAAAAAAACAAACGAGCGCTATTGATGTGAATCCATTTGATGAAAAGGAAACATTTGCGTGGATGGAGGCGATAGCT
AAACAGGAGGGCGTTGCGATCGAGCAAGACGCGAAGCAATTGCTGTATAAGCGTACAGGCCCTAACTTGATGTTGTTGCA
CCGTGAATTGGAGAAGTGCATGTTGTATAGCAAAGACGGGGACCCAGTCACAGCAAGCATTGTCGACGAACTCGTTGCTG
AGACAGTGGAACAAAGTGTATTTACTGTTATTGACTACACGGCGAAAGGCCGTGCTGGTGACGCGGTCCGGCTTTACCAC
CAGCTGTTGAGGCAAAAAGAAGAGCCGCTGGCCATACTGGCGTTGTTGACGCGGCAATTTCGGCAATTTTTCCAGGTGAA
AACGAGGCTAGCCAAAGGGTACACGCAAAAAGAGATGGCATCACAGCTTAAATTGCATCCTTATGTAGTAAAGCTCGCCA
TGCAGCAAGTCAAAGCGTTAACGACCAAGCAATTAAGACAAGCTCTTATCGTTTGCGAAGAAACTGACTATGCCATTAAG
ACAGGGCAGGCCGATAAAGAGTTGGCCGTCGAGCTGTTGCTGCTGCGATTGGCAAGCACGTAA

Upstream 100 bases:

>100_bases
CGATATTATCCGTTAGGCTATGCTACGAAGAGGGAGATTTCTTTCGGAAATATGTTAAAATAAACATGAACAGGTCAGGA
ATATAGGGGATAGGTTGGAT

Downstream 100 bases:

>100_bases
AAAGCCTAAGACTAGCGTCTAAGGCTTTTTGTTTTTGCCATAAAAAAGATCACGGGGCAATGCCCGAGATCTAGCAAGTC
TTATTAAGCAGACAATCCGT

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSIITEMKQLSSETMAPVYFLYGTERYLIEQFLQKASEALFAGEEGEMNDIRLRLQDTPLGEVVEEAETVPFFSKRKLVV
IQDFYLATSQKVATKLEHDIPALEAYLDSPAQETVLVVVAPYEKLDERKKITKKLKKQTSAIDVNPFDEKETFAWMEAIA
KQEGVAIEQDAKQLLYKRTGPNLMLLHRELEKCMLYSKDGDPVTASIVDELVAETVEQSVFTVIDYTAKGRAGDAVRLYH
QLLRQKEEPLAILALLTRQFRQFFQVKTRLAKGYTQKEMASQLKLHPYVVKLAMQQVKALTTKQLRQALIVCEETDYAIK
TGQADKELAVELLLLRLAST

Sequences:

>Translated_340_residues
MSIITEMKQLSSETMAPVYFLYGTERYLIEQFLQKASEALFAGEEGEMNDIRLRLQDTPLGEVVEEAETVPFFSKRKLVV
IQDFYLATSQKVATKLEHDIPALEAYLDSPAQETVLVVVAPYEKLDERKKITKKLKKQTSAIDVNPFDEKETFAWMEAIA
KQEGVAIEQDAKQLLYKRTGPNLMLLHRELEKCMLYSKDGDPVTASIVDELVAETVEQSVFTVIDYTAKGRAGDAVRLYH
QLLRQKEEPLAILALLTRQFRQFFQVKTRLAKGYTQKEMASQLKLHPYVVKLAMQQVKALTTKQLRQALIVCEETDYAIK
TGQADKELAVELLLLRLAST
>Mature_339_residues
SIITEMKQLSSETMAPVYFLYGTERYLIEQFLQKASEALFAGEEGEMNDIRLRLQDTPLGEVVEEAETVPFFSKRKLVVI
QDFYLATSQKVATKLEHDIPALEAYLDSPAQETVLVVVAPYEKLDERKKITKKLKKQTSAIDVNPFDEKETFAWMEAIAK
QEGVAIEQDAKQLLYKRTGPNLMLLHRELEKCMLYSKDGDPVTASIVDELVAETVEQSVFTVIDYTAKGRAGDAVRLYHQ
LLRQKEEPLAILALLTRQFRQFFQVKTRLAKGYTQKEMASQLKLHPYVVKLAMQQVKALTTKQLRQALIVCEETDYAIKT
GQADKELAVELLLLRLAST

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 38718; Mature: 38587

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIITEMKQLSSETMAPVYFLYGTERYLIEQFLQKASEALFAGEEGEMNDIRLRLQDTPL
CCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCH
GEVVEEAETVPFFSKRKLVVIQDFYLATSQKVATKLEHDIPALEAYLDSPAQETVLVVVA
HHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEC
PYEKLDERKKITKKLKKQTSAIDVNPFDEKETFAWMEAIAKQEGVAIEQDAKQLLYKRTG
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
PNLMLLHRELEKCMLYSKDGDPVTASIVDELVAETVEQSVFTVIDYTAKGRAGDAVRLYH
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHH
QLLRQKEEPLAILALLTRQFRQFFQVKTRLAKGYTQKEMASQLKLHPYVVKLAMQQVKAL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TTKQLRQALIVCEETDYAIKTGQADKELAVELLLLRLAST
HHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIITEMKQLSSETMAPVYFLYGTERYLIEQFLQKASEALFAGEEGEMNDIRLRLQDTPL
CHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCH
GEVVEEAETVPFFSKRKLVVIQDFYLATSQKVATKLEHDIPALEAYLDSPAQETVLVVVA
HHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEC
PYEKLDERKKITKKLKKQTSAIDVNPFDEKETFAWMEAIAKQEGVAIEQDAKQLLYKRTG
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
PNLMLLHRELEKCMLYSKDGDPVTASIVDELVAETVEQSVFTVIDYTAKGRAGDAVRLYH
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHH
QLLRQKEEPLAILALLTRQFRQFFQVKTRLAKGYTQKEMASQLKLHPYVVKLAMQQVKAL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TTKQLRQALIVCEETDYAIKTGQADKELAVELLLLRLAST
HHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]