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The map label for this gene is comEB [H]

Identifier: 56963412

GI number: 56963412

Start: 1775105

End: 1775695

Strand: Direct

Name: comEB [H]

Synonym: ABC1647

Alternate gene names: 56963412

Gene position: 1775105-1775695 (Clockwise)

Preceding gene: 56963411

Following gene: 56963413

Centisome position: 41.24

GC content: 45.01

Gene sequence:

>591_bases
ATGGAACGTATTTCATGGGATCAATATTTTTTGGCGCAAAGCAAATTGCTTTCGCTGCGAAGCACATGCCCACGTTTAAA
AGTAGGCGCCACAATTGTGAGAGACAAGCGGATTATTGCAGGCGGCTACAACGGCTCTGTTTCCGGGTCAGACCATTGTC
TTGACAAAGGCTGTTATGTAGTCGACAACCATTGCATCCGTACCGTTCATGCAGAGGTAAATGCGTTGCTGCAATGCGCC
AAATTTGGTGTGCCGACCGCTGGCGCGGAAATTTACATTACACATTTTCCTTGCATTCATTGTACCAAATCGCTGATTCA
AGCTGGCATTGCCCGCGTTTATTATGCAAAGGACTATAAAAACCATCCTTATGCAGAAGAGTTGTTCAAAGAAGCGGGCA
TTCCATGCATAGAAGTGGAACTAGACGAAGCGGCCATTGATCAACAGTTCCATGAGAAGCTTGCCTTAACAACAGCGCTT
TTGCAAGAAATTGAACGGTTAGGGGCAAGCGAAGAAGAATTGGATGCCTATGTAAAGCGAACAAAGAACTTGTATTTCTC
AGCAAGCAATGATGTGCCAGAAGAGAAATGA

Upstream 100 bases:

>100_bases
CGAAAAAACATTCGAAGCACTTGAACCATTGATTCGGGTGAAGTAAAGATTGACTTATGTTGGCGATCGCTTCTACAATT
TAAGCGAAAGGGGAAAAGCA

Downstream 100 bases:

>100_bases
ACCGCCTGTGCATCAGTTTGCTCACAGCGAGCGCAGCTGTTGTGTTCGTTTTAAGCAGCCATGTTGGCGTTGCTGTCGCG
TTGTTTATAGGAGCAATCGC

Product: late competence protein ComEB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MERISWDQYFLAQSKLLSLRSTCPRLKVGATIVRDKRIIAGGYNGSVSGSDHCLDKGCYVVDNHCIRTVHAEVNALLQCA
KFGVPTAGAEIYITHFPCIHCTKSLIQAGIARVYYAKDYKNHPYAEELFKEAGIPCIEVELDEAAIDQQFHEKLALTTAL
LQEIERLGASEEELDAYVKRTKNLYFSASNDVPEEK

Sequences:

>Translated_196_residues
MERISWDQYFLAQSKLLSLRSTCPRLKVGATIVRDKRIIAGGYNGSVSGSDHCLDKGCYVVDNHCIRTVHAEVNALLQCA
KFGVPTAGAEIYITHFPCIHCTKSLIQAGIARVYYAKDYKNHPYAEELFKEAGIPCIEVELDEAAIDQQFHEKLALTTAL
LQEIERLGASEEELDAYVKRTKNLYFSASNDVPEEK
>Mature_196_residues
MERISWDQYFLAQSKLLSLRSTCPRLKVGATIVRDKRIIAGGYNGSVSGSDHCLDKGCYVVDNHCIRTVHAEVNALLQCA
KFGVPTAGAEIYITHFPCIHCTKSLIQAGIARVYYAKDYKNHPYAEELFKEAGIPCIEVELDEAAIDQQFHEKLALTTAL
LQEIERLGASEEELDAYVKRTKNLYFSASNDVPEEK

Specific function: Dispensable for transformability [H]

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=168, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI61742821, Length=168, Percent_Identity=34.5238095238095, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557019, Length=144, Percent_Identity=31.9444444444444, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321938, Length=149, Percent_Identity=33.5570469798658, Blast_Score=91, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24667298, Length=133, Percent_Identity=39.8496240601504, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24667302, Length=133, Percent_Identity=39.8496240601504, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013404
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 21945; Mature: 21945

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERISWDQYFLAQSKLLSLRSTCPRLKVGATIVRDKRIIAGGYNGSVSGSDHCLDKGCYV
CCCCCHHHHHHHHHHHHHHHHCCCCCHHCCEEEECCEEEECCCCCCCCCCCHHHHCCCEE
VDNHCIRTVHAEVNALLQCAKFGVPTAGAEIYITHFPCIHCTKSLIQAGIARVYYAKDYK
ECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC
NHPYAEELFKEAGIPCIEVELDEAAIDQQFHEKLALTTALLQEIERLGASEEELDAYVKR
CCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
TKNLYFSASNDVPEEK
HHCEEEECCCCCCCCC
>Mature Secondary Structure
MERISWDQYFLAQSKLLSLRSTCPRLKVGATIVRDKRIIAGGYNGSVSGSDHCLDKGCYV
CCCCCHHHHHHHHHHHHHHHHCCCCCHHCCEEEECCEEEECCCCCCCCCCCHHHHCCCEE
VDNHCIRTVHAEVNALLQCAKFGVPTAGAEIYITHFPCIHCTKSLIQAGIARVYYAKDYK
ECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC
NHPYAEELFKEAGIPCIEVELDEAAIDQQFHEKLALTTALLQEIERLGASEEELDAYVKR
CCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
TKNLYFSASNDVPEEK
HHCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7968523; 8969508; 9384377 [H]