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The map label for this gene is yrrC [H]

Identifier: 56963353

GI number: 56963353

Start: 1712378

End: 1714663

Strand: Direct

Name: yrrC [H]

Synonym: ABC1588

Alternate gene names: 56963353

Gene position: 1712378-1714663 (Clockwise)

Preceding gene: 56963352

Following gene: 56963354

Centisome position: 39.79

GC content: 46.89

Gene sequence:

>2286_bases
ATGGATAATGTTGGGGAAAAAACGCTGGAGAAAGGTTTTGTTAAAGGAAAAGTCGTTCATGTGTTGTTTCGCAATGAAGA
AAACGATTATACAGTGGCGATGACGCGGATTGAAAAGACGAATGAACAAATAGAAGGGCGCAAAATAACGGTTGTCGGCC
ATTTGCCTGAACTGGAAGTAGAGGAGACCTATTTATTTTTCGGGCAAGTCGCTGAACATCCACGCTTTGGCCTCCAATAC
AAAGTGGAAACGTTTAGGCGCGATTTGCCACAGACGAAAAGCGGAATTATTCGGTTTTTGTCAAGCGACCGTTTCCCTGG
CGTTGGCAAAAAGACAGCGGAAGCAATTGTCGACGCTCTCGGTGAAAGGGCCATTTCAGCTATTATTGAAGATCGAACGG
TATTAAACAACATCCCGAAGCTAAAAGAAGATACAGCGACGATGCTCTATAACCAACTTCTTGAGCAACAAGGCGCGGAG
CAAGTCATTATCCAACTGTCCCAATACGGGTTTGGCACAGAGTTGTCGATGAGTGTTTACCGAACGTACAAATTGCAAGC
ACTTGATGTTATCCGCACCAACCCGTATTTGCTCATTCAGGATGTAGAAGGAGTCGGCTTTCGCCGTGCAGACCAATTAG
GGGCGGCGATTGGCTTAACTGGGAACCATCCAGAGCGTTTGCGGGCGGGGCTGCTTTATTTGCTCCGGGAATGTTGTATG
CAACAAGGACATTTATACTTGCAGGAGGAAGCGCTCATTACGGAGGGGACTGCATTATTATCGAGCCCAAACGTACAAAT
TGACGCTTCCGAGCTTGAGGCCATCCTCATCGAAATGAATGAAGAGGGCATGCTCGTTCGTGAAGAAGACCGCATCTACA
TGAAGTCATTGTATTATGCAGAAAAAGGCATTGCCACCAACATCCGCCGAATTTTAAGCCAAGAACTGACACAAGAATTC
ACTGAAGCAGACATTGAAAAAACACTCGGGCACATTGAGGATACACATGCTGTTACGTATTCAAACACGCAAAAAGAAGC
GATTGCCACTGCTCTTCGTTCTCCGCTGTTGTTGCTGACAGGAGGGCCTGGAACAGGAAAGACTACGGTCATTAAAGGAA
TTGTGGAAGCTTATGCTGCGCTTCATGGGCTTTCTCTTGAAGTGGCTGCTTACAAAAACAAATCTTTCCCCCTTAAGTTG
ACTGCGCCCACTGGTCGAGCCAGCAAACGGATGGCTGAAGCAACGGAACTGCCTGCAAGCACGATACACAGCTTGCTCGG
CTGGAAAGGCAGTGCGACCGGCTTTGAAAAAGGCGACCATGAACAGCTTGAAGGGGAACTGCTAATTGTCGATGAGATGT
CGATGGTCGATGCCTGGGTTGCAAATCAGTTATTTAAAGCGATTCCCAAAGGCATGCAAGTCGTGTTAGTAGGGGATGAA
AACCAGTTGCCTTCTGTAGGGCCTGGCCAAGTATTAAAAGACCTTTTAGAAGCAGACGTTATTCCAACAATCCAATTAAA
GGACATTTACAGGCAAGCTGAAGGCTCTTCCATCATTGAGCTTGCCCACTCGATGAAAGATGGCGTGCTTCCAAGTGATT
TTTTAACGAAAAAGGCAGACCGCGTCTTTTTTCCTTGCCAGCCGAACCAAGTGCAACAAGCAGTTTGGCAAATTTGTGAA
AACGCCATGAAGAAAGGCTACAGTGCTAAGGAGATCCAAGTACTGGCACCCATGTACCGCGGGCAGGCAGGGATCAATGA
ATTAAACACGATGCTTCAGTCCCTATTTAATCCGGCAAAAGAAGGTCGCAGAGAGCTGCCGTTTGGGGATGTTGTTTTTC
GCAAAGGCGATATGGTCCTCCAGTTAGTCAACAATCCAGAGGAAGGCGTATACAACGGCGATAGAGGAGAAATTGTTGCT
GTTTTCTACGCTAAAGAGACGACGGAAAAAAAAGATCAGCTAGTGGTTTCCTTTGACGGACTGGAAGTCACCTATGAGAA
AAAAGACTTTTCACAGCTAACCCATGCCTATTGCTGTTCTATCCATAAAGCACAAGGAAGCGAATTTCCGATTGTGGTGA
TGCCAGTCGTGTCGAGCTACATGCGCATGCTGAGGCGGAACTTGCTTTATACAGGCATTACCCGGGCCAAGCAGTATTTG
CTCTTATGTGGCGATCGAAAAACGATGGAACAGGCGATTAAACATGCAGACGAGCACCGCCATTCCAAATTAAAGGAGCG
CCTTCAACTATTGCTTTCACGTACTGGTAACGTTCACCGGGGATAG

Upstream 100 bases:

>100_bases
CTTGCCTCTTTTAACCAAGCGCTTGCCCACCAACCGGGCCATCTTCTCGCTGGCAACGGCAAACGGCTTATTGAAGCGAC
ACTTGAAAAAGGGTGAAGCT

Downstream 100 bases:

>100_bases
AGGAAGCTACATATGCATAACTTAAGACTGTTCGGAAAGGCGGTGTTTCTTTGCGAACAGTTCAAGCGCTTATAGGGCTT
CCTGTTATCAGCAATACAAC

Product: ATP-dependent exoDNAse alpha subunit

Products: Hydrolyzed double-stranded DNA [C]

Alternate protein names: NA

Number of amino acids: Translated: 761; Mature: 761

Protein sequence:

>761_residues
MDNVGEKTLEKGFVKGKVVHVLFRNEENDYTVAMTRIEKTNEQIEGRKITVVGHLPELEVEETYLFFGQVAEHPRFGLQY
KVETFRRDLPQTKSGIIRFLSSDRFPGVGKKTAEAIVDALGERAISAIIEDRTVLNNIPKLKEDTATMLYNQLLEQQGAE
QVIIQLSQYGFGTELSMSVYRTYKLQALDVIRTNPYLLIQDVEGVGFRRADQLGAAIGLTGNHPERLRAGLLYLLRECCM
QQGHLYLQEEALITEGTALLSSPNVQIDASELEAILIEMNEEGMLVREEDRIYMKSLYYAEKGIATNIRRILSQELTQEF
TEADIEKTLGHIEDTHAVTYSNTQKEAIATALRSPLLLLTGGPGTGKTTVIKGIVEAYAALHGLSLEVAAYKNKSFPLKL
TAPTGRASKRMAEATELPASTIHSLLGWKGSATGFEKGDHEQLEGELLIVDEMSMVDAWVANQLFKAIPKGMQVVLVGDE
NQLPSVGPGQVLKDLLEADVIPTIQLKDIYRQAEGSSIIELAHSMKDGVLPSDFLTKKADRVFFPCQPNQVQQAVWQICE
NAMKKGYSAKEIQVLAPMYRGQAGINELNTMLQSLFNPAKEGRRELPFGDVVFRKGDMVLQLVNNPEEGVYNGDRGEIVA
VFYAKETTEKKDQLVVSFDGLEVTYEKKDFSQLTHAYCCSIHKAQGSEFPIVVMPVVSSYMRMLRRNLLYTGITRAKQYL
LLCGDRKTMEQAIKHADEHRHSKLKERLQLLLSRTGNVHRG

Sequences:

>Translated_761_residues
MDNVGEKTLEKGFVKGKVVHVLFRNEENDYTVAMTRIEKTNEQIEGRKITVVGHLPELEVEETYLFFGQVAEHPRFGLQY
KVETFRRDLPQTKSGIIRFLSSDRFPGVGKKTAEAIVDALGERAISAIIEDRTVLNNIPKLKEDTATMLYNQLLEQQGAE
QVIIQLSQYGFGTELSMSVYRTYKLQALDVIRTNPYLLIQDVEGVGFRRADQLGAAIGLTGNHPERLRAGLLYLLRECCM
QQGHLYLQEEALITEGTALLSSPNVQIDASELEAILIEMNEEGMLVREEDRIYMKSLYYAEKGIATNIRRILSQELTQEF
TEADIEKTLGHIEDTHAVTYSNTQKEAIATALRSPLLLLTGGPGTGKTTVIKGIVEAYAALHGLSLEVAAYKNKSFPLKL
TAPTGRASKRMAEATELPASTIHSLLGWKGSATGFEKGDHEQLEGELLIVDEMSMVDAWVANQLFKAIPKGMQVVLVGDE
NQLPSVGPGQVLKDLLEADVIPTIQLKDIYRQAEGSSIIELAHSMKDGVLPSDFLTKKADRVFFPCQPNQVQQAVWQICE
NAMKKGYSAKEIQVLAPMYRGQAGINELNTMLQSLFNPAKEGRRELPFGDVVFRKGDMVLQLVNNPEEGVYNGDRGEIVA
VFYAKETTEKKDQLVVSFDGLEVTYEKKDFSQLTHAYCCSIHKAQGSEFPIVVMPVVSSYMRMLRRNLLYTGITRAKQYL
LLCGDRKTMEQAIKHADEHRHSKLKERLQLLLSRTGNVHRG
>Mature_761_residues
MDNVGEKTLEKGFVKGKVVHVLFRNEENDYTVAMTRIEKTNEQIEGRKITVVGHLPELEVEETYLFFGQVAEHPRFGLQY
KVETFRRDLPQTKSGIIRFLSSDRFPGVGKKTAEAIVDALGERAISAIIEDRTVLNNIPKLKEDTATMLYNQLLEQQGAE
QVIIQLSQYGFGTELSMSVYRTYKLQALDVIRTNPYLLIQDVEGVGFRRADQLGAAIGLTGNHPERLRAGLLYLLRECCM
QQGHLYLQEEALITEGTALLSSPNVQIDASELEAILIEMNEEGMLVREEDRIYMKSLYYAEKGIATNIRRILSQELTQEF
TEADIEKTLGHIEDTHAVTYSNTQKEAIATALRSPLLLLTGGPGTGKTTVIKGIVEAYAALHGLSLEVAAYKNKSFPLKL
TAPTGRASKRMAEATELPASTIHSLLGWKGSATGFEKGDHEQLEGELLIVDEMSMVDAWVANQLFKAIPKGMQVVLVGDE
NQLPSVGPGQVLKDLLEADVIPTIQLKDIYRQAEGSSIIELAHSMKDGVLPSDFLTKKADRVFFPCQPNQVQQAVWQICE
NAMKKGYSAKEIQVLAPMYRGQAGINELNTMLQSLFNPAKEGRRELPFGDVVFRKGDMVLQLVNNPEEGVYNGDRGEIVA
VFYAKETTEKKDQLVVSFDGLEVTYEKKDFSQLTHAYCCSIHKAQGSEFPIVVMPVVSSYMRMLRRNLLYTGITRAKQYL
LLCGDRKTMEQAIKHADEHRHSKLKERLQLLLSRTGNVHRG

Specific function: Exhibits Several Catalytic Activities, Including ATP-Dependent Exonuclease, ATP-Stimulated Endonuclease, ATP-Dependent Unwinding And DNA-Dependent ATPase Activities. Strand Cleavage Occurs 5' To 3' During The Unwinding Of Duplex DNA At Chi Sequences, Whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789182, Length=529, Percent_Identity=24.007561436673, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR006345 [H]

Pfam domain/function: NA

EC number: 3.1.11.5 [C]

Molecular weight: Translated: 85165; Mature: 85165

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNVGEKTLEKGFVKGKVVHVLFRNEENDYTVAMTRIEKTNEQIEGRKITVVGHLPELEV
CCCCHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEEHHHHHHHCCCCEEEEEECCCCCCH
EETYLFFGQVAEHPRFGLQYKVETFRRDLPQTKSGIIRFLSSDRFPGVGKKTAEAIVDAL
HHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
GERAISAIIEDRTVLNNIPKLKEDTATMLYNQLLEQQGAEQVIIQLSQYGFGTELSMSVY
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEHHHH
RTYKLQALDVIRTNPYLLIQDVEGVGFRRADQLGAAIGLTGNHPERLRAGLLYLLRECCM
HHHHHEEEEEEECCCEEEEEECCCCCCCCHHHHCCEEECCCCCHHHHHHHHHHHHHHHHH
QQGHLYLQEEALITEGTALLSSPNVQIDASELEAILIEMNEEGMLVREEDRIYMKSLYYA
HCCCEEEECCHHHCCCCHHCCCCCCEEEHHHHEEEEEEECCCCCEEECCCHHHHHHHHHH
EKGIATNIRRILSQELTQEFTEADIEKTLGHIEDTHAVTYSNTQKEAIATALRSPLLLLT
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHCCCEEEEE
GGPGTGKTTVIKGIVEAYAALHGLSLEVAAYKNKSFPLKLTAPTGRASKRMAEATELPAS
CCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHCCCHH
TIHSLLGWKGSATGFEKGDHEQLEGELLIVDEMSMVDAWVANQLFKAIPKGMQVVLVGDE
HHHHHHCCCCCCCCCCCCCCHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCEEEEECCC
NQLPSVGPGQVLKDLLEADVIPTIQLKDIYRQAEGSSIIELAHSMKDGVLPSDFLTKKAD
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCCCC
RVFFPCQPNQVQQAVWQICENAMKKGYSAKEIQVLAPMYRGQAGINELNTMLQSLFNPAK
CEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHH
EGRRELPFGDVVFRKGDMVLQLVNNPEEGVYNGDRGEIVAVFYAKETTEKKDQLVVSFDG
HCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECC
LEVTYEKKDFSQLTHAYCCSIHKAQGSEFPIVVMPVVSSYMRMLRRNLLYTGITRAKQYL
EEEEECHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHEE
LLCGDRKTMEQAIKHADEHRHSKLKERLQLLLSRTGNVHRG
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDNVGEKTLEKGFVKGKVVHVLFRNEENDYTVAMTRIEKTNEQIEGRKITVVGHLPELEV
CCCCHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEEHHHHHHHCCCCEEEEEECCCCCCH
EETYLFFGQVAEHPRFGLQYKVETFRRDLPQTKSGIIRFLSSDRFPGVGKKTAEAIVDAL
HHHHHHHHHHHCCCCCCCEEEHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
GERAISAIIEDRTVLNNIPKLKEDTATMLYNQLLEQQGAEQVIIQLSQYGFGTELSMSVY
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEHHHH
RTYKLQALDVIRTNPYLLIQDVEGVGFRRADQLGAAIGLTGNHPERLRAGLLYLLRECCM
HHHHHEEEEEEECCCEEEEEECCCCCCCCHHHHCCEEECCCCCHHHHHHHHHHHHHHHHH
QQGHLYLQEEALITEGTALLSSPNVQIDASELEAILIEMNEEGMLVREEDRIYMKSLYYA
HCCCEEEECCHHHCCCCHHCCCCCCEEEHHHHEEEEEEECCCCCEEECCCHHHHHHHHHH
EKGIATNIRRILSQELTQEFTEADIEKTLGHIEDTHAVTYSNTQKEAIATALRSPLLLLT
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHCCCEEEEE
GGPGTGKTTVIKGIVEAYAALHGLSLEVAAYKNKSFPLKLTAPTGRASKRMAEATELPAS
CCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCEEEECCCCHHHHHHHHHHCCCHH
TIHSLLGWKGSATGFEKGDHEQLEGELLIVDEMSMVDAWVANQLFKAIPKGMQVVLVGDE
HHHHHHCCCCCCCCCCCCCCHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCEEEEECCC
NQLPSVGPGQVLKDLLEADVIPTIQLKDIYRQAEGSSIIELAHSMKDGVLPSDFLTKKAD
CCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHCCCC
RVFFPCQPNQVQQAVWQICENAMKKGYSAKEIQVLAPMYRGQAGINELNTMLQSLFNPAK
CEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCHHH
EGRRELPFGDVVFRKGDMVLQLVNNPEEGVYNGDRGEIVAVFYAKETTEKKDQLVVSFDG
HCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECC
LEVTYEKKDFSQLTHAYCCSIHKAQGSEFPIVVMPVVSSYMRMLRRNLLYTGITRAKQYL
EEEEECHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHEE
LLCGDRKTMEQAIKHADEHRHSKLKERLQLLLSRTGNVHRG
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Double-stranded DNA; H2O; DNA [C]

Specific reaction: Double-stranded DNA + H2O = Hydrolyzed double-stranded DNA Protein + DNA = Protein-DNA [C]

General reaction: DNA-dependent ATPase activity; Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]