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The map label for this gene is dtd

Identifier: 56963336

GI number: 56963336

Start: 1693265

End: 1693705

Strand: Direct

Name: dtd

Synonym: ABC1571

Alternate gene names: 56963336

Gene position: 1693265-1693705 (Clockwise)

Preceding gene: 56963335

Following gene: 56963337

Centisome position: 39.34

GC content: 46.03

Gene sequence:

>441_bases
GTGCGAGTACTAGTCCAGCGAGCGAAACGGGGCAGTGTTCGAGTCGACCAAAAAACAGTAGGCGACATTGGGCCAGGCCT
TGTCCTCTTAGTTGGAATTCATCAAGAAGATACAGAAGCGGACGTACGTTTTTGTGCGGAAAAAGTAGCCCATTTGCGCA
TTTTTGAAGACAGCTCTGCCAAAATGAATGAATCGGTACTCGATCAAGGCGGTTCCGTCTTATCGATTTCACAATTTACG
CTTTATGGAGACTGTAAAAAAGGACGTCGTCCTAATTTCATGCGTGCTGCTAAGCCTGAAAAGGCAAAGCTGCTTTATGA
ACGTTTTAACAGCTATTTGCGAGAGCTCGGCCTTGTTGTGGAAACGGGCGAGTTTGGGGCGATGATGGAAGTAGAGTTAA
TTAATGATGGGCCGGTAACGATTTTAGTTGAAAGCGAGTAA

Upstream 100 bases:

>100_bases
TATCGCTCATTTGCAAAAAGTGGTCGACAAAATTAAACAGTTAAAAGACATTTACTCTGTGCGGAGGGTAACCCATTAGA
GTCGAGGCAGGTGAGAAAAA

Downstream 100 bases:

>100_bases
GCGCTTGTCGTCTTAATCGTGTTGACATCTTCATTTAAGGGGGATCCGAATAAGACGAGTGTTGCGAGCCGATACTTGCA
CAAACGAAAATGTATACGAG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MRVLVQRAKRGSVRVDQKTVGDIGPGLVLLVGIHQEDTEADVRFCAEKVAHLRIFEDSSAKMNESVLDQGGSVLSISQFT
LYGDCKKGRRPNFMRAAKPEKAKLLYERFNSYLRELGLVVETGEFGAMMEVELINDGPVTILVESE

Sequences:

>Translated_146_residues
MRVLVQRAKRGSVRVDQKTVGDIGPGLVLLVGIHQEDTEADVRFCAEKVAHLRIFEDSSAKMNESVLDQGGSVLSISQFT
LYGDCKKGRRPNFMRAAKPEKAKLLYERFNSYLRELGLVVETGEFGAMMEVELINDGPVTILVESE
>Mature_146_residues
MRVLVQRAKRGSVRVDQKTVGDIGPGLVLLVGIHQEDTEADVRFCAEKVAHLRIFEDSSAKMNESVLDQGGSVLSISQFT
LYGDCKKGRRPNFMRAAKPEKAKLLYERFNSYLRELGLVVETGEFGAMMEVELINDGPVTILVESE

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=40.9395973154362, Blast_Score=103, Evalue=7e-23,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=43.0555555555556, Blast_Score=127, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=40.9395973154362, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6319982, Length=149, Percent_Identity=44.2953020134228, Blast_Score=118, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281361569, Length=150, Percent_Identity=43.3333333333333, Blast_Score=112, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_BACSK (Q5WHP9)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175067.1
- ProteinModelPortal:   Q5WHP9
- SMR:   Q5WHP9
- STRING:   Q5WHP9
- EnsemblBacteria:   EBBACT00000046489
- GeneID:   3203732
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1571
- NMPDR:   fig|66692.3.peg.1533
- eggNOG:   COG1490
- GeneTree:   EBGT00050000002392
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   BCLA66692:ABC1571-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16246; Mature: 16246

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVQRAKRGSVRVDQKTVGDIGPGLVLLVGIHQEDTEADVRFCAEKVAHLRIFEDSSA
CCHHHHHHCCCCEEECCHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEECCCCC
KMNESVLDQGGSVLSISQFTLYGDCKKGRRPNFMRAAKPEKAKLLYERFNSYLRELGLVV
CCCHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGEFGAMMEVELINDGPVTILVESE
ECCCCCCEEEEEEECCCCEEEEEECC
>Mature Secondary Structure
MRVLVQRAKRGSVRVDQKTVGDIGPGLVLLVGIHQEDTEADVRFCAEKVAHLRIFEDSSA
CCHHHHHHCCCCEEECCHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHEEEECCCCC
KMNESVLDQGGSVLSISQFTLYGDCKKGRRPNFMRAAKPEKAKLLYERFNSYLRELGLVV
CCCHHHHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGEFGAMMEVELINDGPVTILVESE
ECCCCCCEEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA