Click here to switch to the map view.

The map label for this gene is secF [H]

Identifier: 56963331

GI number: 56963331

Start: 1686744

End: 1687679

Strand: Direct

Name: secF [H]

Synonym: ABC1566

Alternate gene names: 56963331

Gene position: 1686744-1687679 (Clockwise)

Preceding gene: 56963330

Following gene: 56963332

Centisome position: 39.19

GC content: 42.41

Gene sequence:

>936_bases
ATGAGCTTTAATCCGGAAAAGTGGAATGTCGATTTGACAAAACACCGAAAACGTTTTTTTATCGGCTCGGGCTTGTCAAT
TGTCCTTGGAATTGTGTTGTTGCTTACGTTTGGTTTAAACTTAGGCGTTGATTTTGAAAGTGGCTCGAATGTGGAAATTC
AAGCGGATCAGACATTGATGCAAGAACAATTACTGGACGACTTTGCAGCAATCAATGAATCGTACACGCCGAATATTACA
CTTGGAGGCGAGCAAAGCCAAAGTGCGACTGCTCGGTTTACAGTGGAACTTTCCAAAGATGAAATTACCGCGATTCAAAC
TTATTTCCAAGACAAATACGGCCATTCGCCTAACGTCAGTACAGTGTCGCCTCTCGTCGGCCAGGAGCTTGCTCGCAATG
CGATTTTGTCCGTATTGATCGCTTCATTAGGGATTGTCATTTATATCGGCTTCCGTTTTCACTTCTTATATGGGGTTTCA
GCGGTTATTGGCTTGCTCCATGATGCCTTTATCATTATTGCGTTGTTCAGCTTGTTCCAAGTTGAAATTAATGTGCCTTT
TATAGCGGCAGTGCTTACTGTTGTTGGCTATTCAATCAATGACACGATTGTTACGTTTGACCGAATGCGGGAAAATATTA
ACAAGGAGAAGGAAATTAAAAGCTTTGAGCACTTGGCGCAAATTGTAAACAAAAGTTTGCTTCAAGTGTTAACACGCTCG
ATCAATACAGTATTGACCGTGCTATTTGCCGCTGTGGCATTGCTGATTTTCGGCGGCGAAGCGATCCGCTCGTTTTCATT
GGCTCTTGTCATTGGATTGATTGCCGGTACTTATTCTTCGATGTTCCTTTGTGCGCAAATATGGCTTGTCTGGGAGTGGA
AGCGGCAAAAGAAACTAAAAAACAAACCAAAGAAAACGGAAGAAGAGTACATTTGA

Upstream 100 bases:

>100_bases
ACGGCCGTTTATGGTTCCAGAGTATTGCTAGGCCTTTGGGTGAACAGCAAATTTTTAAATAAACGACCTGGCTGGTTTGG
CGTGAAAAGAGGTGAAATTG

Downstream 100 bases:

>100_bases
GCGGAGGGGATTGACATGAAAGCACAGACAGCGTTTATTATCGGCATTATTGCCGCCATTATCATTGCTGTGTTTGCGGT
GTTAAATGTGGAAAGCGTAC

Product: preprotein translocase subunit SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSFNPEKWNVDLTKHRKRFFIGSGLSIVLGIVLLLTFGLNLGVDFESGSNVEIQADQTLMQEQLLDDFAAINESYTPNIT
LGGEQSQSATARFTVELSKDEITAIQTYFQDKYGHSPNVSTVSPLVGQELARNAILSVLIASLGIVIYIGFRFHFLYGVS
AVIGLLHDAFIIIALFSLFQVEINVPFIAAVLTVVGYSINDTIVTFDRMRENINKEKEIKSFEHLAQIVNKSLLQVLTRS
INTVLTVLFAAVALLIFGGEAIRSFSLALVIGLIAGTYSSMFLCAQIWLVWEWKRQKKLKNKPKKTEEEYI

Sequences:

>Translated_311_residues
MSFNPEKWNVDLTKHRKRFFIGSGLSIVLGIVLLLTFGLNLGVDFESGSNVEIQADQTLMQEQLLDDFAAINESYTPNIT
LGGEQSQSATARFTVELSKDEITAIQTYFQDKYGHSPNVSTVSPLVGQELARNAILSVLIASLGIVIYIGFRFHFLYGVS
AVIGLLHDAFIIIALFSLFQVEINVPFIAAVLTVVGYSINDTIVTFDRMRENINKEKEIKSFEHLAQIVNKSLLQVLTRS
INTVLTVLFAAVALLIFGGEAIRSFSLALVIGLIAGTYSSMFLCAQIWLVWEWKRQKKLKNKPKKTEEEYI
>Mature_310_residues
SFNPEKWNVDLTKHRKRFFIGSGLSIVLGIVLLLTFGLNLGVDFESGSNVEIQADQTLMQEQLLDDFAAINESYTPNITL
GGEQSQSATARFTVELSKDEITAIQTYFQDKYGHSPNVSTVSPLVGQELARNAILSVLIASLGIVIYIGFRFHFLYGVSA
VIGLLHDAFIIIALFSLFQVEINVPFIAAVLTVVGYSINDTIVTFDRMRENINKEKEIKSFEHLAQIVNKSLLQVLTRSI
NTVLTVLFAAVALLIFGGEAIRSFSLALVIGLIAGTYSSMFLCAQIWLVWEWKRQKKLKNKPKKTEEEYI

Specific function: Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane [H]

COG id: COG0341

COG function: function code U; Preprotein translocase subunit SecF

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786610, Length=299, Percent_Identity=30.4347826086957, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 34721; Mature: 34590

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNPEKWNVDLTKHRKRFFIGSGLSIVLGIVLLLTFGLNLGVDFESGSNVEIQADQTLM
CCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEECCCCCCEEEEHHHHHH
QEQLLDDFAAINESYTPNITLGGEQSQSATARFTVELSKDEITAIQTYFQDKYGHSPNVS
HHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCC
TVSPLVGQELARNAILSVLIASLGIVIYIGFRFHFLYGVSAVIGLLHDAFIIIALFSLFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEINVPFIAAVLTVVGYSINDTIVTFDRMRENINKEKEIKSFEHLAQIVNKSLLQVLTRS
HHCCCHHHHHHHHHHCCCCCCHHEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
INTVLTVLFAAVALLIFGGEAIRSFSLALVIGLIAGTYSSMFLCAQIWLVWEWKRQKKLK
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NKPKKTEEEYI
CCCCCCCCCCC
>Mature Secondary Structure 
SFNPEKWNVDLTKHRKRFFIGSGLSIVLGIVLLLTFGLNLGVDFESGSNVEIQADQTLM
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEECCCCCCEEEEHHHHHH
QEQLLDDFAAINESYTPNITLGGEQSQSATARFTVELSKDEITAIQTYFQDKYGHSPNVS
HHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCCC
TVSPLVGQELARNAILSVLIASLGIVIYIGFRFHFLYGVSAVIGLLHDAFIIIALFSLFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEINVPFIAAVLTVVGYSINDTIVTFDRMRENINKEKEIKSFEHLAQIVNKSLLQVLTRS
HHCCCHHHHHHHHHHCCCCCCHHEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
INTVLTVLFAAVALLIFGGEAIRSFSLALVIGLIAGTYSSMFLCAQIWLVWEWKRQKKLK
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NKPKKTEEEYI
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9694879; 9384377 [H]