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The map label for this gene is secD [H]

Identifier: 56963330

GI number: 56963330

Start: 1685453

End: 1686754

Strand: Direct

Name: secD [H]

Synonym: ABC1565

Alternate gene names: 56963330

Gene position: 1685453-1686754 (Clockwise)

Preceding gene: 56963329

Following gene: 56963331

Centisome position: 39.16

GC content: 43.47

Gene sequence:

>1302_bases
ATGGTTAAAAAAGGCAAAATTGCGCTTTTCTTTCTCATTATTGCGTTGTTTGCTTCTGGAATCGCCTATTTTGCAAAGCC
TGTTGTAAACGACGTCAGCCTTGGGCTTGACTTGCAAGGCGGCTTTGAAGTGCTTTACGAAGTGGAGCCCATGAATGAAG
GCGATGAAATTAATCAGGATTCGCTTTTAGCAACAACGACTGCATTGAATGAAAGGGTAAATACAATTGGCGTTTCAGAA
CCGAACATTCAAATTGAAGGAGAAAACCGGATCCGTGTCCAGTTAGCTGGCGTTGAAGACCAAGAAACAGCACGTGACAT
TTTGGCGACTGGTGCAGAATTGACGATCCGTGACGTCGATGACAACGTGCTTCTTGATGGCAGCGATTTAACCCAAAATG
GTGCCAGCGCATCGGTACATCCAGAAAAGAATCAGCCGATTGTGACGTTGACGCTAAATGATGCAGACAAATTTGGCGAA
ATCACACGTGAAATTTCTGAACGTCCACTAGGAGAGAATTTGCTCGTCATCTGGCTTGACTTCGAAGAAGGCGATAGCTT
TGCAGAAGAATCAAAAAAACAAGACCCTAAATACATGTCAGCAGCGTCCGTTAATGCCCCGTTACATACACGAGACGTAA
TGATTGAAGGGAATTTTACAACGGAGGAAACACGCTTTCTTGCTGAAATATTAAATGCAGGCGCCTTGCCTGTTGAATTA
AATGAGATCTACTCTACATCTGTCGGTGCATCGCTAGGAGAAAAAGCGATGAACCAAACGATTTTTGCTGGCTCCCTTGG
GGTTGCGCTGATCTTTTTGTATATGGTGGTTTACTATCGCTTCCCAGGAATCATTGCTGTCATTACACTAAGCATCTATA
CATTTTTGGTGCTTGTCGTCTTTAATGCAATGAATGCTGTGTTAACTTTGCCAGGCATTGCTGCACTCGTGCTTGGGGTT
GGCATGGCTGTCGATGCGAATATCATTACTTATGAACGGATTAAGGAAGAGATTAAATCAGGGAAATCGATTTTATCTGC
CTTTAAAGTCGGCAGCAGGCGCTCGTTTGCAACGATTTTTGATGCCAATATTACGACGTTGATTGCGGCTGGCGTTATGT
TTTATTTTGGTACGAGCTCCGTGCAAGGTTTTGCGGTCATGCTCATTATTAGCATTCTTGTCAGCTTTTTAACGGCCGTT
TATGGTTCCAGAGTATTGCTAGGCCTTTGGGTGAACAGCAAATTTTTAAATAAACGACCTGGCTGGTTTGGCGTGAAAAG
AGGTGAAATTGATGAGCTTTAA

Upstream 100 bases:

>100_bases
GTCCATGCGTATAAGGAGCCGATTGACTGGTTCAAAACATTTGAGCAAGCAACAGCCGAAAAGTAACAGATTCGAGATTG
CGTAGGAGGATAAACAGACT

Downstream 100 bases:

>100_bases
TCCGGAAAAGTGGAATGTCGATTTGACAAAACACCGAAAACGTTTTTTTATCGGCTCGGGCTTGTCAATTGTCCTTGGAA
TTGTGTTGTTGCTTACGTTT

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MVKKGKIALFFLIIALFASGIAYFAKPVVNDVSLGLDLQGGFEVLYEVEPMNEGDEINQDSLLATTTALNERVNTIGVSE
PNIQIEGENRIRVQLAGVEDQETARDILATGAELTIRDVDDNVLLDGSDLTQNGASASVHPEKNQPIVTLTLNDADKFGE
ITREISERPLGENLLVIWLDFEEGDSFAEESKKQDPKYMSAASVNAPLHTRDVMIEGNFTTEETRFLAEILNAGALPVEL
NEIYSTSVGASLGEKAMNQTIFAGSLGVALIFLYMVVYYRFPGIIAVITLSIYTFLVLVVFNAMNAVLTLPGIAALVLGV
GMAVDANIITYERIKEEIKSGKSILSAFKVGSRRSFATIFDANITTLIAAGVMFYFGTSSVQGFAVMLIISILVSFLTAV
YGSRVLLGLWVNSKFLNKRPGWFGVKRGEIDEL

Sequences:

>Translated_433_residues
MVKKGKIALFFLIIALFASGIAYFAKPVVNDVSLGLDLQGGFEVLYEVEPMNEGDEINQDSLLATTTALNERVNTIGVSE
PNIQIEGENRIRVQLAGVEDQETARDILATGAELTIRDVDDNVLLDGSDLTQNGASASVHPEKNQPIVTLTLNDADKFGE
ITREISERPLGENLLVIWLDFEEGDSFAEESKKQDPKYMSAASVNAPLHTRDVMIEGNFTTEETRFLAEILNAGALPVEL
NEIYSTSVGASLGEKAMNQTIFAGSLGVALIFLYMVVYYRFPGIIAVITLSIYTFLVLVVFNAMNAVLTLPGIAALVLGV
GMAVDANIITYERIKEEIKSGKSILSAFKVGSRRSFATIFDANITTLIAAGVMFYFGTSSVQGFAVMLIISILVSFLTAV
YGSRVLLGLWVNSKFLNKRPGWFGVKRGEIDEL
>Mature_433_residues
MVKKGKIALFFLIIALFASGIAYFAKPVVNDVSLGLDLQGGFEVLYEVEPMNEGDEINQDSLLATTTALNERVNTIGVSE
PNIQIEGENRIRVQLAGVEDQETARDILATGAELTIRDVDDNVLLDGSDLTQNGASASVHPEKNQPIVTLTLNDADKFGE
ITREISERPLGENLLVIWLDFEEGDSFAEESKKQDPKYMSAASVNAPLHTRDVMIEGNFTTEETRFLAEILNAGALPVEL
NEIYSTSVGASLGEKAMNQTIFAGSLGVALIFLYMVVYYRFPGIIAVITLSIYTFLVLVVFNAMNAVLTLPGIAALVLGV
GMAVDANIITYERIKEEIKSGKSILSAFKVGSRRSFATIFDANITTLIAAGVMFYFGTSSVQGFAVMLIISILVSFLTAV
YGSRVLLGLWVNSKFLNKRPGWFGVKRGEIDEL

Specific function: Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=385, Percent_Identity=29.8701298701299, Blast_Score=168, Evalue=8e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 47123; Mature: 47123

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKKGKIALFFLIIALFASGIAYFAKPVVNDVSLGLDLQGGFEVLYEVEPMNEGDEINQD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEEEEECCCCCCCCCCCC
SLLATTTALNERVNTIGVSEPNIQIEGENRIRVQLAGVEDQETARDILATGAELTIRDVD
HHHHHHHHHHHHHHEECCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHCCCEEEEEECC
DNVLLDGSDLTQNGASASVHPEKNQPIVTLTLNDADKFGEITREISERPLGENLLVIWLD
CCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEE
FEEGDSFAEESKKQDPKYMSAASVNAPLHTRDVMIEGNFTTEETRFLAEILNAGALPVEL
ECCCCCHHHHHHCCCCCHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEH
NEIYSTSVGASLGEKAMNQTIFAGSLGVALIFLYMVVYYRFPGIIAVITLSIYTFLVLVV
HHHHHHHHCHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FNAMNAVLTLPGIAALVLGVGMAVDANIITYERIKEEIKSGKSILSAFKVGSRRSFATIF
HHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DANITTLIAAGVMFYFGTSSVQGFAVMLIISILVSFLTAVYGSRVLLGLWVNSKFLNKRP
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHCCCC
GWFGVKRGEIDEL
CCCCCCCCCCCCC
>Mature Secondary Structure
MVKKGKIALFFLIIALFASGIAYFAKPVVNDVSLGLDLQGGFEVLYEVEPMNEGDEINQD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEEEEECCCCCCCCCCCC
SLLATTTALNERVNTIGVSEPNIQIEGENRIRVQLAGVEDQETARDILATGAELTIRDVD
HHHHHHHHHHHHHHEECCCCCCEEEECCCEEEEEEECCCCHHHHHHHHHCCCEEEEEECC
DNVLLDGSDLTQNGASASVHPEKNQPIVTLTLNDADKFGEITREISERPLGENLLVIWLD
CCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEE
FEEGDSFAEESKKQDPKYMSAASVNAPLHTRDVMIEGNFTTEETRFLAEILNAGALPVEL
ECCCCCHHHHHHCCCCCHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEH
NEIYSTSVGASLGEKAMNQTIFAGSLGVALIFLYMVVYYRFPGIIAVITLSIYTFLVLVV
HHHHHHHHCHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FNAMNAVLTLPGIAALVLGVGMAVDANIITYERIKEEIKSGKSILSAFKVGSRRSFATIF
HHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
DANITTLIAAGVMFYFGTSSVQGFAVMLIISILVSFLTAVYGSRVLLGLWVNSKFLNKRP
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHCCCC
GWFGVKRGEIDEL
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9694879; 9384377 [H]