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The map label for this gene is obgE

Identifier: 56963307

GI number: 56963307

Start: 1665468

End: 1666754

Strand: Direct

Name: obgE

Synonym: ABC1542

Alternate gene names: 56963307

Gene position: 1665468-1666754 (Clockwise)

Preceding gene: 56963306

Following gene: 56963308

Centisome position: 38.7

GC content: 49.18

Gene sequence:

>1287_bases
ATGTTTGTCGATAAAGTGAAAGTATACGCCAAAGGTGGAGACGGCGGGAACGGCATGGTGGCTTATCGAAGAGAAAAATA
TGTGCCTGACGGCGGACCAGCCGGAGGAGACGGCGGCCGCGGTGCCAGTGTTATCCTTGAAGTGGATGAAGGCTTGCGGA
CATTAATGGATTTCCGCTACAACAAACATTTTAAAGGAAAACGGGGCGAGCACGGCATGTCTAAAAACATGCACGGCAAA
AAGGCCGAAGACTTAGTTGTGAAAGTTCCTCCTGGTACGATGGTAACCGATGAGGAGACAGGGGCGCTGCTTGCTGACTT
GACTACACACGGCCAACGGGCTGTTGTGGCTAAAGGTGGTCGAGGGGGGCGGGGAAATGTCCGTTTTGTAACACCTGCCA
ACCCTGCTCCAGACCATGCAGAAAATGGCGAGCCAGGGGAAGAACGGAATTTGCTCCTTGAATTAAAAGTGCTTGCCGAC
GTTGGATTGGTTGGTTTTCCTAGTGTCGGAAAATCGACGCTTCTGTCGATTGTGTCGGCTGCTAAACCAAAGATTGCTGA
ATACCACTTTACAACGATTACACCAAACCTTGGGGTAGTGGATACACAGGACGGGCGCAGTTTTGTCATGGCAGATTTGC
CTGGTTTAATCGAAGGCGCCCATGAAGGCGTTGGGCTCGGTCACCAATTTTTGCGGCATATTGAGCGGACGCGCGTCATT
GTCCATATTGTAGATATGTCGGCAATGGAAGGGCGTGATCCTGTGGAAGACTATCACAAAATTAATGAAGAACTATCCCA
GTACAATTACCGGTTGACGGAGCGCCCCCAATTAGTGGTTGCTAATAAAATGGACATGCCAGAAGCAAATGAAAACCTTA
AGCGATTTAAAGAGGCACTTGGCGAGGAAACGAAAATTTTTCCAGTTTCGGCGATCACGAAAGACGGTGTCCGTGAATTG
ATGCTAGCGATTGCTGATGAATTGGAGCATGCGCCAGAGTTTCCATTGCATGACAGCGAAGAGCAAGTAGAGGGCAGAGT
GCTTTATAAACATGAATTGCCAATTGAGCCGTTTACAATCACCCGTGGAGACGATGGCGTGTTTGAATTATCGGGAGCTG
AACTGGAGCGTGCCTTTAAAATGACTGATTTTGCTAGGGAAGAATCTGTACGCCGCTTTGCCCGGAGGATGAGGAAAATG
GGCGTTGATGAAGCGTTGCGGAAGCGAGGCGCAAAAGACGGCGACCTAGTCCGGATTATGAAATTTGAATTCGAGTTTGT
CGAATGA

Upstream 100 bases:

>100_bases
TTCAGTCGTCGTCGACGTAACTAGGCAAGAACAAGCAGGTTATACAGTAACGTTTTTACTGGATGCAACAGCTTCCAATT
AGGAAATGGAGTGAACGAAG

Downstream 100 bases:

>100_bases
GTTAGTCGGGCCAGGCAGTCTATGCTGTACTGGCCTTTTTTAAAAGGAGTAAAGCTATATCCAATTGCTTCTGGTACCTT
CCCCTAAATGATTTGTTGAA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MFVDKVKVYAKGGDGGNGMVAYRREKYVPDGGPAGGDGGRGASVILEVDEGLRTLMDFRYNKHFKGKRGEHGMSKNMHGK
KAEDLVVKVPPGTMVTDEETGALLADLTTHGQRAVVAKGGRGGRGNVRFVTPANPAPDHAENGEPGEERNLLLELKVLAD
VGLVGFPSVGKSTLLSIVSAAKPKIAEYHFTTITPNLGVVDTQDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHIVDMSAMEGRDPVEDYHKINEELSQYNYRLTERPQLVVANKMDMPEANENLKRFKEALGEETKIFPVSAITKDGVREL
MLAIADELEHAPEFPLHDSEEQVEGRVLYKHELPIEPFTITRGDDGVFELSGAELERAFKMTDFAREESVRRFARRMRKM
GVDEALRKRGAKDGDLVRIMKFEFEFVE

Sequences:

>Translated_428_residues
MFVDKVKVYAKGGDGGNGMVAYRREKYVPDGGPAGGDGGRGASVILEVDEGLRTLMDFRYNKHFKGKRGEHGMSKNMHGK
KAEDLVVKVPPGTMVTDEETGALLADLTTHGQRAVVAKGGRGGRGNVRFVTPANPAPDHAENGEPGEERNLLLELKVLAD
VGLVGFPSVGKSTLLSIVSAAKPKIAEYHFTTITPNLGVVDTQDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHIVDMSAMEGRDPVEDYHKINEELSQYNYRLTERPQLVVANKMDMPEANENLKRFKEALGEETKIFPVSAITKDGVREL
MLAIADELEHAPEFPLHDSEEQVEGRVLYKHELPIEPFTITRGDDGVFELSGAELERAFKMTDFAREESVRRFARRMRKM
GVDEALRKRGAKDGDLVRIMKFEFEFVE
>Mature_428_residues
MFVDKVKVYAKGGDGGNGMVAYRREKYVPDGGPAGGDGGRGASVILEVDEGLRTLMDFRYNKHFKGKRGEHGMSKNMHGK
KAEDLVVKVPPGTMVTDEETGALLADLTTHGQRAVVAKGGRGGRGNVRFVTPANPAPDHAENGEPGEERNLLLELKVLAD
VGLVGFPSVGKSTLLSIVSAAKPKIAEYHFTTITPNLGVVDTQDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
VHIVDMSAMEGRDPVEDYHKINEELSQYNYRLTERPQLVVANKMDMPEANENLKRFKEALGEETKIFPVSAITKDGVREL
MLAIADELEHAPEFPLHDSEEQVEGRVLYKHELPIEPFTITRGDDGVFELSGAELERAFKMTDFAREESVRRFARRMRKM
GVDEALRKRGAKDGDLVRIMKFEFEFVE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=42.3676012461059, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI111955139, Length=377, Percent_Identity=35.8090185676393, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI111955063, Length=272, Percent_Identity=35.6617647058824, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=38.135593220339, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4557537, Length=89, Percent_Identity=42.6966292134831, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI58761500, Length=129, Percent_Identity=34.1085271317829, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1789574, Length=343, Percent_Identity=49.2711370262391, Blast_Score=304, Evalue=7e-84,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=34.7826086956522, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790615, Length=170, Percent_Identity=28.8235294117647, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=321, Percent_Identity=38.3177570093458, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=328, Percent_Identity=28.6585365853659, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=31.6546762589928, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=153, Percent_Identity=32.0261437908497, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=36.4406779661017, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=37.1134020618557, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=38.0952380952381, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=34.9206349206349, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24585318, Length=373, Percent_Identity=35.3887399463807, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI20129375, Length=323, Percent_Identity=39.6284829721362, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI17981711, Length=134, Percent_Identity=35.8208955223881, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356473, Length=117, Percent_Identity=38.4615384615385, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=36.71875, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=36.71875, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=36.71875, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_BACSK (Q5WHS8)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175038.1
- HSSP:   P20964
- ProteinModelPortal:   Q5WHS8
- SMR:   Q5WHS8
- STRING:   Q5WHS8
- EnsemblBacteria:   EBBACT00000047914
- GeneID:   3202054
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1542
- NMPDR:   fig|66692.3.peg.1916
- eggNOG:   COG0536
- GeneTree:   EBGT00050000000577
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12297
- BioCyc:   BCLA66692:ABC1542-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 47406; Mature: 47406

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDKVKVYAKGGDGGNGMVAYRREKYVPDGGPAGGDGGRGASVILEVDEGLRTLMDFRY
CCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHC
NKHFKGKRGEHGMSKNMHGKKAEDLVVKVPPGTMVTDEETGALLADLTTHGQRAVVAKGG
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCEEEHHHCCCCEEEEEECC
RGGRGNVRFVTPANPAPDHAENGEPGEERNLLLELKVLADVGLVGFPSVGKSTLLSIVSA
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
AKPKIAEYHFTTITPNLGVVDTQDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
CCCCCEEEEEEEECCCCCEEECCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHIVDMSAMEGRDPVEDYHKINEELSQYNYRLTERPQLVVANKMDMPEANENLKRFKEAL
EEEECCHHCCCCCCHHHHHHHHHHHHHHCCEECCCCCEEEECCCCCCCCHHHHHHHHHHH
GEETKIFPVSAITKDGVRELMLAIADELEHAPEFPLHDSEEQVEGRVLYKHELPIEPFTI
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECCCCCCEEE
TRGDDGVFELSGAELERAFKMTDFAREESVRRFARRMRKMGVDEALRKRGAKDGDLVRIM
ECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEEE
KFEFEFVE
EEEEEECC
>Mature Secondary Structure
MFVDKVKVYAKGGDGGNGMVAYRREKYVPDGGPAGGDGGRGASVILEVDEGLRTLMDFRY
CCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHC
NKHFKGKRGEHGMSKNMHGKKAEDLVVKVPPGTMVTDEETGALLADLTTHGQRAVVAKGG
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCEEEHHHCCCCEEEEEECC
RGGRGNVRFVTPANPAPDHAENGEPGEERNLLLELKVLADVGLVGFPSVGKSTLLSIVSA
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
AKPKIAEYHFTTITPNLGVVDTQDGRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVI
CCCCCEEEEEEEECCCCCEEECCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHIVDMSAMEGRDPVEDYHKINEELSQYNYRLTERPQLVVANKMDMPEANENLKRFKEAL
EEEECCHHCCCCCCHHHHHHHHHHHHHHCCEECCCCCEEEECCCCCCCCHHHHHHHHHHH
GEETKIFPVSAITKDGVRELMLAIADELEHAPEFPLHDSEEQVEGRVLYKHELPIEPFTI
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEEEECCCCCCEEE
TRGDDGVFELSGAELERAFKMTDFAREESVRRFARRMRKMGVDEALRKRGAKDGDLVRIM
ECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEEEE
KFEFEFVE
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA