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The map label for this gene is glpD [H]

Identifier: 56963263

GI number: 56963263

Start: 1619752

End: 1621359

Strand: Direct

Name: glpD [H]

Synonym: ABC1498

Alternate gene names: 56963263

Gene position: 1619752-1621359 (Clockwise)

Preceding gene: 56963262

Following gene: 56963264

Centisome position: 37.63

GC content: 44.59

Gene sequence:

>1608_bases
ATGGTTCATTCTTTTTCAAGTGAATTGCGGGGTGAGTATATACAGCAGCTGGAAGGGGATGTCTTCGATCTACTAGTAAT
CGGTGGCGGGGTTGCAGGAGCGGGCATCGCCCTTGATGCAGTAGTCAGGGGAATGAAGACTGTTTTAATTGAACGAGCCG
ATTTTGCTTCAGGTTCTTCAGGTGCCTGGTCAACCCTTTTTCATAATGAGAGTAGGCAGGCCCACCAGCTTGACATGAAA
TGGCACGGAGAATATGTCAAAGAGCGCTTGATTTTGCATGAAAATGCTCCGCATTTAATGAAACAGCTTCCTTTGCTGCT
TCCTGCTTTTAAAGTCGGCATGTTTGGCAGGCATTCTTTTGGTTCAAAGGTAGTTGAACGTATATCAGACTTAGCAAGAA
AGGAAAAGCGCAAACATTTATCAAAAAAAGAACTGAATCGCCTTGCGCCTTTGCTTTCTGACAAATCGATCAAAGGCGCT
GTTCTCTACCAAGAATTTTGGCGGGACGATGCACGGCTCGTATTTGACTTATTAAAAGAAGCAACTAGAAGGGGAGCAAT
GGCACTCAATTATATGAAAGCAGAGACATTTCTCTATGAAAATGGGAAAGCTGTCGGTGTGGTTGCGATCGATCAGTTGA
CTGGCGAAGCTTATAAAGTGTTCGCTAAAAAGATTATTAATGCGACAGGGATTGAGGCAGATACTCTACGGGAGCAAGAC
CGGTCTATGTCGGCCAAGACGATTGGCTATATGACTGATGTTTATATGGTCATTCCAAAAGAGCTGCTTGCGATTGACCA
AGTTGTTTATTTGGAATTGGACGACAAAAAGCTGATTAGTCTGGCGCCAAGGGGCAAGAAAGTCGTATTGTCTTTGACGG
ACAGCGATGAAAAGGACAAAAACGAACGAGAGGTCATGTTGGCGAAAATCAATCAGACGTTTCAGGAAGTACAGATTACA
CCTGATGATATTGAAGCCTCATGGCATGTTAAACGGCCAATTGTGATTGAAACAAATAAAAAAAAGCATGAAGCGATCAG
GAAAAATGACTGGTTTGAATCCGCTTCTGGCCTTGTAACAGTCGTATGTGGACACACCACTGGTTATCGTTTATTGGCCC
AGCAAATTCTTGACCGTATCGCCAAAAAAGCAGGCCCTTTTTCTCCGTGCGAAACGGATACAGTCACCCTTTCTGGCGGC
TATGCAGGCAGCGTTGACCAATTTGACAATTATAAAGAAAAGCGCCTCGCTGAAGGGGTGCAGTATGGAATCAGCCAAGA
AAAGGCACAAGAATTAGTCGATATGTATGGTTCGAATGTAGGGGCCATTTATGCACGCTTTTGGTCTTATAAAAAACAAG
CACGTCTATTTGGGTTGCCGCCGGTTATTTTTGCACAGCTGCTGTTTTCGATTGAAGAAGAAATGGCGGTTACGCCCGCA
GACTTTTTAGTCAGGCGCACGGCGATGTTCTACTTTAATAAAACAGAAGCGTTACATGTCCAGGAAGCGGTTTTTCGCTA
CATGCGTGATCGCTTTAATTGGAGCGAAGAGCAGGAAGCGCAATACCGAGTGGAATTGGATGCCTTGATCAAGCCTGCAA
GCAGGTAA

Upstream 100 bases:

>100_bases
TTTGTTTAAAAAATCGGATTCCGGTTGTCGTCTGACTTCTCTGTTATTGTGAAAAAATGCTATGATAAGGAAAGTGAGCA
AACAGATTGGGGAGTTGTAG

Downstream 100 bases:

>100_bases
GCCGTTTTTTTGCTGGCAAACCAGTGGAATGCTGTGTAAAATGATAGCGTAGAGCAGTTTTTATGGGAGGGACTCTTTTG
AATATTGTGGAGAAAGTGGA

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MVHSFSSELRGEYIQQLEGDVFDLLVIGGGVAGAGIALDAVVRGMKTVLIERADFASGSSGAWSTLFHNESRQAHQLDMK
WHGEYVKERLILHENAPHLMKQLPLLLPAFKVGMFGRHSFGSKVVERISDLARKEKRKHLSKKELNRLAPLLSDKSIKGA
VLYQEFWRDDARLVFDLLKEATRRGAMALNYMKAETFLYENGKAVGVVAIDQLTGEAYKVFAKKIINATGIEADTLREQD
RSMSAKTIGYMTDVYMVIPKELLAIDQVVYLELDDKKLISLAPRGKKVVLSLTDSDEKDKNEREVMLAKINQTFQEVQIT
PDDIEASWHVKRPIVIETNKKKHEAIRKNDWFESASGLVTVVCGHTTGYRLLAQQILDRIAKKAGPFSPCETDTVTLSGG
YAGSVDQFDNYKEKRLAEGVQYGISQEKAQELVDMYGSNVGAIYARFWSYKKQARLFGLPPVIFAQLLFSIEEEMAVTPA
DFLVRRTAMFYFNKTEALHVQEAVFRYMRDRFNWSEEQEAQYRVELDALIKPASR

Sequences:

>Translated_535_residues
MVHSFSSELRGEYIQQLEGDVFDLLVIGGGVAGAGIALDAVVRGMKTVLIERADFASGSSGAWSTLFHNESRQAHQLDMK
WHGEYVKERLILHENAPHLMKQLPLLLPAFKVGMFGRHSFGSKVVERISDLARKEKRKHLSKKELNRLAPLLSDKSIKGA
VLYQEFWRDDARLVFDLLKEATRRGAMALNYMKAETFLYENGKAVGVVAIDQLTGEAYKVFAKKIINATGIEADTLREQD
RSMSAKTIGYMTDVYMVIPKELLAIDQVVYLELDDKKLISLAPRGKKVVLSLTDSDEKDKNEREVMLAKINQTFQEVQIT
PDDIEASWHVKRPIVIETNKKKHEAIRKNDWFESASGLVTVVCGHTTGYRLLAQQILDRIAKKAGPFSPCETDTVTLSGG
YAGSVDQFDNYKEKRLAEGVQYGISQEKAQELVDMYGSNVGAIYARFWSYKKQARLFGLPPVIFAQLLFSIEEEMAVTPA
DFLVRRTAMFYFNKTEALHVQEAVFRYMRDRFNWSEEQEAQYRVELDALIKPASR
>Mature_535_residues
MVHSFSSELRGEYIQQLEGDVFDLLVIGGGVAGAGIALDAVVRGMKTVLIERADFASGSSGAWSTLFHNESRQAHQLDMK
WHGEYVKERLILHENAPHLMKQLPLLLPAFKVGMFGRHSFGSKVVERISDLARKEKRKHLSKKELNRLAPLLSDKSIKGA
VLYQEFWRDDARLVFDLLKEATRRGAMALNYMKAETFLYENGKAVGVVAIDQLTGEAYKVFAKKIINATGIEADTLREQD
RSMSAKTIGYMTDVYMVIPKELLAIDQVVYLELDDKKLISLAPRGKKVVLSLTDSDEKDKNEREVMLAKINQTFQEVQIT
PDDIEASWHVKRPIVIETNKKKHEAIRKNDWFESASGLVTVVCGHTTGYRLLAQQILDRIAKKAGPFSPCETDTVTLSGG
YAGSVDQFDNYKEKRLAEGVQYGISQEKAQELVDMYGSNVGAIYARFWSYKKQARLFGLPPVIFAQLLFSIEEEMAVTPA
DFLVRRTAMFYFNKTEALHVQEAVFRYMRDRFNWSEEQEAQYRVELDALIKPASR

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=535, Percent_Identity=29.5327102803738, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI285002231, Length=535, Percent_Identity=29.5327102803738, Blast_Score=186, Evalue=4e-47,
Organism=Escherichia coli, GI2367226, Length=496, Percent_Identity=23.3870967741935, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788574, Length=395, Percent_Identity=22.0253164556962, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17509253, Length=537, Percent_Identity=29.2364990689013, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI115534726, Length=527, Percent_Identity=26.7552182163188, Blast_Score=158, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6322036, Length=585, Percent_Identity=27.8632478632479, Blast_Score=169, Evalue=9e-43,
Organism=Drosophila melanogaster, GI161077125, Length=549, Percent_Identity=28.4153005464481, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653942, Length=549, Percent_Identity=28.4153005464481, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653944, Length=549, Percent_Identity=28.4153005464481, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI20130025, Length=549, Percent_Identity=28.4153005464481, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24586295, Length=525, Percent_Identity=26.4761904761905, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI19921278, Length=548, Percent_Identity=26.2773722627737, Blast_Score=148, Evalue=9e-36,
Organism=Drosophila melanogaster, GI45550977, Length=395, Percent_Identity=23.7974683544304, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 60627; Mature: 60627

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHSFSSELRGEYIQQLEGDVFDLLVIGGGVAGAGIALDAVVRGMKTVLIERADFASGSS
CCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
GAWSTLFHNESRQAHQLDMKWHGEYVKERLILHENAPHLMKQLPLLLPAFKVGMFGRHSF
CCCHHHHCCCCCHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHH
GSKVVERISDLARKEKRKHLSKKELNRLAPLLSDKSIKGAVLYQEFWRDDARLVFDLLKE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHH
ATRRGAMALNYMKAETFLYENGKAVGVVAIDQLTGEAYKVFAKKIINATGIEADTLREQD
HHHCCHHHHHHHHHHHEEEECCCEEEEEEEEHHCCHHHHHHHHHHHHCCCCCHHHHHHHH
RSMSAKTIGYMTDVYMVIPKELLAIDQVVYLELDDKKLISLAPRGKKVVLSLTDSDEKDK
HCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHEEECCCCCEEEEEECCCCCCCC
NEREVMLAKINQTFQEVQITPDDIEASWHVKRPIVIETNKKKHEAIRKNDWFESASGLVT
CHHHHHHHHHHHHHHHEECCCCCCCCCEEECCCEEEECCCHHHHHHHHCCCHHCCCCEEE
VVCGHTTGYRLLAQQILDRIAKKAGPFSPCETDTVTLSGGYAGSVDQFDNYKEKRLAEGV
EEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
QYGISQEKAQELVDMYGSNVGAIYARFWSYKKQARLFGLPPVIFAQLLFSIEEEMAVTPA
HHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH
DFLVRRTAMFYFNKTEALHVQEAVFRYMRDRFNWSEEQEAQYRVELDALIKPASR
HHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEHHHHCCCCCC
>Mature Secondary Structure
MVHSFSSELRGEYIQQLEGDVFDLLVIGGGVAGAGIALDAVVRGMKTVLIERADFASGSS
CCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
GAWSTLFHNESRQAHQLDMKWHGEYVKERLILHENAPHLMKQLPLLLPAFKVGMFGRHSF
CCCHHHHCCCCCHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHH
GSKVVERISDLARKEKRKHLSKKELNRLAPLLSDKSIKGAVLYQEFWRDDARLVFDLLKE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHH
ATRRGAMALNYMKAETFLYENGKAVGVVAIDQLTGEAYKVFAKKIINATGIEADTLREQD
HHHCCHHHHHHHHHHHEEEECCCEEEEEEEEHHCCHHHHHHHHHHHHCCCCCHHHHHHHH
RSMSAKTIGYMTDVYMVIPKELLAIDQVVYLELDDKKLISLAPRGKKVVLSLTDSDEKDK
HCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHEEECCCCCEEEEEECCCCCCCC
NEREVMLAKINQTFQEVQITPDDIEASWHVKRPIVIETNKKKHEAIRKNDWFESASGLVT
CHHHHHHHHHHHHHHHEECCCCCCCCCEEECCCEEEECCCHHHHHHHHCCCHHCCCCEEE
VVCGHTTGYRLLAQQILDRIAKKAGPFSPCETDTVTLSGGYAGSVDQFDNYKEKRLAEGV
EEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHH
QYGISQEKAQELVDMYGSNVGAIYARFWSYKKQARLFGLPPVIFAQLLFSIEEEMAVTPA
HHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH
DFLVRRTAMFYFNKTEALHVQEAVFRYMRDRFNWSEEQEAQYRVELDALIKPASR
HHHHHHHHHHEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]