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The map label for this gene is qacR [H]

Identifier: 56963188

GI number: 56963188

Start: 1536020

End: 1536601

Strand: Direct

Name: qacR [H]

Synonym: ABC1423

Alternate gene names: 56963188

Gene position: 1536020-1536601 (Clockwise)

Preceding gene: 56963182

Following gene: 56963189

Centisome position: 35.69

GC content: 29.04

Gene sequence:

>582_bases
ATGAGTGAACAAAAAAAGAAGATCATCTCAGCAGCTAGAAATTTATTTCAAACAAAAGGTTTTTCAGAAACCTCAATGAA
TCAAATTATAGAAGCTGCACAATCAAGTAAAGGGAATTTGTATCACCATTTCAAAAACAAAGAAAATCTGTTTGTATATA
TTCTTGAAGAAGATGCTAATCAATGGCTGAAAGATTGGAAAATAGAAGCTGAAAAAAAACAAAATAATTCAAACCATATT
TTATATACACTCTCAGAATTTGTAGCCAAGTCAAGCGTTAACCTTTATTACCATAAAGCAACAGAAGAGTTTTATCTTAG
TGCGTTCAAATCAGACGAGGTCATGAAAAAGATTAAAAATATAGATAAACTATACCTTGATTTTTTTGTGGATATTATTA
AGGAATGCCAAACGTCTAAACAAATCAACCAAAATGAAGACCCGAGCGTATTAGGCTATTTTCTTATGAGTCTATTATTT
ATAAGTAGTGATTATAAACATTATTATGATGATTTTGAGGAAAATGAGAATAATTTTCATAAGAAAGCCATAGATATTTT
CTTAAATGGGGTAAGAAGGTAG

Upstream 100 bases:

>100_bases
AAAGCTATAATTACTAGTGTATAAGCGACTCCTGTTTGCGAAGTAATCCATTCCATACTATTATGTTTATAATTACTACT
TCAATATAAGGAGCACTATA

Downstream 100 bases:

>100_bases
CATAAATTTCGCTTCCTTCGAATCCCTGTTGTTAAATATATTTTTTTATATTACAATAGACCGAACGGTCTGTCTGTTAT
TGAGAGGAGAGTAAATGTCA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSEQKKKIISAARNLFQTKGFSETSMNQIIEAAQSSKGNLYHHFKNKENLFVYILEEDANQWLKDWKIEAEKKQNNSNHI
LYTLSEFVAKSSVNLYYHKATEEFYLSAFKSDEVMKKIKNIDKLYLDFFVDIIKECQTSKQINQNEDPSVLGYFLMSLLF
ISSDYKHYYDDFEENENNFHKKAIDIFLNGVRR

Sequences:

>Translated_193_residues
MSEQKKKIISAARNLFQTKGFSETSMNQIIEAAQSSKGNLYHHFKNKENLFVYILEEDANQWLKDWKIEAEKKQNNSNHI
LYTLSEFVAKSSVNLYYHKATEEFYLSAFKSDEVMKKIKNIDKLYLDFFVDIIKECQTSKQINQNEDPSVLGYFLMSLLF
ISSDYKHYYDDFEENENNFHKKAIDIFLNGVRR
>Mature_192_residues
SEQKKKIISAARNLFQTKGFSETSMNQIIEAAQSSKGNLYHHFKNKENLFVYILEEDANQWLKDWKIEAEKKQNNSNHIL
YTLSEFVAKSSVNLYYHKATEEFYLSAFKSDEVMKKIKNIDKLYLDFFVDIIKECQTSKQINQNEDPSVLGYFLMSLLFI
SSDYKHYYDDFEENENNFHKKAIDIFLNGVRR

Specific function: Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013571
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08360 TetR_C_5; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22891; Mature: 22760

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQKKKIISAARNLFQTKGFSETSMNQIIEAAQSSKGNLYHHFKNKENLFVYILEEDAN
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCHH
QWLKDWKIEAEKKQNNSNHILYTLSEFVAKSSVNLYYHKATEEFYLSAFKSDEVMKKIKN
HHHHHHCCCCHHCCCCCCEEEEEHHHHHHHCCCCEEEEHHHHHHHHHHHCHHHHHHHHHH
IDKLYLDFFVDIIKECQTSKQINQNEDPSVLGYFLMSLLFISSDYKHYYDDFEENENNFH
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHH
KKAIDIFLNGVRR
HHHHHHHHHHCCC
>Mature Secondary Structure 
SEQKKKIISAARNLFQTKGFSETSMNQIIEAAQSSKGNLYHHFKNKENLFVYILEEDAN
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCHH
QWLKDWKIEAEKKQNNSNHILYTLSEFVAKSSVNLYYHKATEEFYLSAFKSDEVMKKIKN
HHHHHHCCCCHHCCCCCCEEEEEHHHHHHHCCCCEEEEHHHHHHHHHHHCHHHHHHHHHH
IDKLYLDFFVDIIKECQTSKQINQNEDPSVLGYFLMSLLFISSDYKHYYDDFEENENNFH
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHH
KKAIDIFLNGVRR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]