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The map label for this gene is mta [H]

Identifier: 56963166

GI number: 56963166

Start: 1507758

End: 1508558

Strand: Direct

Name: mta [H]

Synonym: ABC1395

Alternate gene names: 56963166

Gene position: 1507758-1508558 (Clockwise)

Preceding gene: 56963164

Following gene: 56963167

Centisome position: 35.03

GC content: 43.07

Gene sequence:

>801_bases
ATGGATGAAACCTATTCAATTGGTCAATGTTCGAAACTGACGGGCGTCCCAGTGAGAACGCTCCACTATTATGAAGAGTT
AGGTCTTTTAAACCCACTTAGACAGGCAAACGGGCATCGGGTATATCAGATTGAGGACATGGTAGAATTACAGAAAATAT
TGAGTTTGAAGGCGCTTGGCTTTAGTCTAACCCAAATAGGTGAACTGTTGAAACTGCCAAAATTTGATCAATCTCTGGTT
GAGACGTTGAGGTTGCAACAGCAAGCGTTGGAAGTAAAGCTTGTAAAGATAAAACAATCTCTTGAACTGATAAGCCGTAT
GATGGCAATCGTTCAGTCTGAGGATCAATTGGAGCATCCGCTATTGTTCAGTCTGATTCGCAATATGAACCAAGAAGATA
TGCAGCGAGAGTGGGTGGCGAACCATCTATCCGAGTATACAGCACAAACGCTATTTGATCGGTCAGCGGAAGCGATAAAG
AAAATGGATGCGAAAACGGTGCGCTTCTCCCGAGATGTGAAACGATTATCGCATGGTCCGAGCAATTCACAGGAAGCTGA
GACCGTGATCGGTGCATACGTGAACTGGGCAATGACTTACATTGATCAAAAGGCAATCGACAATTTTAGAAACTTGGATG
AGGAACAGCTTACCCAACTTGACCAATTAGTGGAGATGCCATTAAATGAAAAGGAGACAGCATGGTTGGATAAGGCACTG
GAACATTATTTTTCTAAATATATGTTGACTGAGCAAGGCGAGCTAACAGCGAGTGCTCCTATTATTACCCGAGAATCATG
A

Upstream 100 bases:

>100_bases
CTTGCTAGACTTCCTATCTCTATCTACCAAACCATACTAAATAAAGCTTGCGCCTACAGTTACTGTAGGTATTACAATCA
GGATAAAAGGAGGCAGTCAA

Downstream 100 bases:

>100_bases
AAGTTGCGTAGAATGGGATCGTTCACTCACAATTAAACGGAGGTGCAAAATAGTGAAAAAAGAAAAGGTGGAACAACAAT
TCAAGGCATTATTCGAAGAC

Product: transcriptional activator of multidrug-efflux transporter genes

Products: NA

Alternate protein names: Multidrug transporter activation protein [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MDETYSIGQCSKLTGVPVRTLHYYEELGLLNPLRQANGHRVYQIEDMVELQKILSLKALGFSLTQIGELLKLPKFDQSLV
ETLRLQQQALEVKLVKIKQSLELISRMMAIVQSEDQLEHPLLFSLIRNMNQEDMQREWVANHLSEYTAQTLFDRSAEAIK
KMDAKTVRFSRDVKRLSHGPSNSQEAETVIGAYVNWAMTYIDQKAIDNFRNLDEEQLTQLDQLVEMPLNEKETAWLDKAL
EHYFSKYMLTEQGELTASAPIITRES

Sequences:

>Translated_266_residues
MDETYSIGQCSKLTGVPVRTLHYYEELGLLNPLRQANGHRVYQIEDMVELQKILSLKALGFSLTQIGELLKLPKFDQSLV
ETLRLQQQALEVKLVKIKQSLELISRMMAIVQSEDQLEHPLLFSLIRNMNQEDMQREWVANHLSEYTAQTLFDRSAEAIK
KMDAKTVRFSRDVKRLSHGPSNSQEAETVIGAYVNWAMTYIDQKAIDNFRNLDEEQLTQLDQLVEMPLNEKETAWLDKAL
EHYFSKYMLTEQGELTASAPIITRES
>Mature_266_residues
MDETYSIGQCSKLTGVPVRTLHYYEELGLLNPLRQANGHRVYQIEDMVELQKILSLKALGFSLTQIGELLKLPKFDQSLV
ETLRLQQQALEVKLVKIKQSLELISRMMAIVQSEDQLEHPLLFSLIRNMNQEDMQREWVANHLSEYTAQTLFDRSAEAIK
KMDAKTVRFSRDVKRLSHGPSNSQEAETVIGAYVNWAMTYIDQKAIDNFRNLDEEQLTQLDQLVEMPLNEKETAWLDKAL
EHYFSKYMLTEQGELTASAPIITRES

Specific function: Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 30725; Mature: 30725

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCCCCCCCCEECCC
>Mature Secondary Structure
MDETYSIGQCSKLTGVPVRTLHYYEELGLLNPLRQANGHRVYQIEDMVELQKILSLKALG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHH
FSLTQIGELLKLPKFDQSLVETLRLQQQALEVKLVKIKQSLELISRMMAIVQSEDQLEHP
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LLFSLIRNMNQEDMQREWVANHLSEYTAQTLFDRSAEAIKKMDAKTVRFSRDVKRLSHGP
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SNSQEAETVIGAYVNWAMTYIDQKAIDNFRNLDEEQLTQLDQLVEMPLNEKETAWLDKAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
EHYFSKYMLTEQGELTASAPIITRES
HHHHHHHHHCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9150240; 9384377 [H]