Click here to switch to the map view.

The map label for this gene is ycdW [C]

Identifier: 56963092

GI number: 56963092

Start: 1437797

End: 1438759

Strand: Direct

Name: ycdW [C]

Synonym: ABC1320

Alternate gene names: 56963092

Gene position: 1437797-1438759 (Clockwise)

Preceding gene: 56963091

Following gene: 56963093

Centisome position: 33.41

GC content: 40.91

Gene sequence:

>963_bases
ATGAGTGAGAACGCATCGGTTGTTTTCTTTATGAAACAAACAGAGGAAAGGCAAGAGCTACTTAAACACTCTTTTGCGAA
TACGTCCTTTTATTTTCCTGATAAAAAAGGTGTTCCTAGCGATCAAATTTTAAAAACGGCGGATGTTCTTGTTACGTTTG
GCGACGATATTACGGAATCGCTTGTGAGCAAAGCGTCTTCACTTAAGTGGATTCACGTCATGTCAGCTGGCATTGAAGGG
TTGCCTCTGCGCCTTTTGCATGATAGAGGTGTGTTGGTAACCAATAGCAGAGGCATTCATGCTGAGCCGATGTCCGAACA
CGCCATTTGGGCGATGCTTGATTATGTAAAACACGCTACTCGTTATCGGATGTTGCAACAAAACAAACAATGGGATAAAA
GCATCAAGCCGAAGGAACTTACTGGGATGACAGCTGTTTTTCTTGGCACGGGCGCCATCGCTTCAAAAACGGCTGAACGG
GCCAACATGTTTGGTATGCGAACAATTGGCGTTAATACAGATGGCCGTCCGCAAAAACATTTTGAGCAGACATTTTCTAT
AGAAGAATGGGATAAAGCATTGAGGAAGGCTGATGTTCTGATCAACATCCTTCCTTATACAGAACAAACGCATGGCATTT
TGAATAAAGAGGCGTTTAGGCAACTTAAGGGGCACACAGTATTTATTAATTTGGGTAGAGGAAAATCCGTAGTTGAAACG
GATTTGCTCGATGCATTAAAATTAAAACAAATTGATCACGCTTATTTAGATGTTTTTGCAGAAGAACCGCTTCCCCTTGA
TTCACCTTTGTGGGACGATAAGGCGGTGACGATTACTCCTCATGTTTCGGCAGCAACATCCCATTACATGAAAAGAGCTC
TTGATATTTTTATGAAAAATTTAAAAGCCTTTATAAACAACGAGGATCTTAAAAACATCGTTTGTTTTGAAAAAGGATAC
TAA

Upstream 100 bases:

>100_bases
TTTGTAATTGGCAAAGACTTTACGGTTCTCAAAGAATGGCGCAATGTAAAAGTGAAAAACCATGTTGATGATGTACTCGC
TTTTGTTAAGGGACAAAATG

Downstream 100 bases:

>100_bases
AGGGAGGGATCAAAACGATGAAGCTGTTAGTATGCATTATTGATGATTTTTACGCTGATGATGTAGAAAAAGATTTGCGC
AAACAAGGGTATCGGATGAC

Product: hypothetical protein

Products: NADPH; glyoxylate; glycerate [C]

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSENASVVFFMKQTEERQELLKHSFANTSFYFPDKKGVPSDQILKTADVLVTFGDDITESLVSKASSLKWIHVMSAGIEG
LPLRLLHDRGVLVTNSRGIHAEPMSEHAIWAMLDYVKHATRYRMLQQNKQWDKSIKPKELTGMTAVFLGTGAIASKTAER
ANMFGMRTIGVNTDGRPQKHFEQTFSIEEWDKALRKADVLINILPYTEQTHGILNKEAFRQLKGHTVFINLGRGKSVVET
DLLDALKLKQIDHAYLDVFAEEPLPLDSPLWDDKAVTITPHVSAATSHYMKRALDIFMKNLKAFINNEDLKNIVCFEKGY

Sequences:

>Translated_320_residues
MSENASVVFFMKQTEERQELLKHSFANTSFYFPDKKGVPSDQILKTADVLVTFGDDITESLVSKASSLKWIHVMSAGIEG
LPLRLLHDRGVLVTNSRGIHAEPMSEHAIWAMLDYVKHATRYRMLQQNKQWDKSIKPKELTGMTAVFLGTGAIASKTAER
ANMFGMRTIGVNTDGRPQKHFEQTFSIEEWDKALRKADVLINILPYTEQTHGILNKEAFRQLKGHTVFINLGRGKSVVET
DLLDALKLKQIDHAYLDVFAEEPLPLDSPLWDDKAVTITPHVSAATSHYMKRALDIFMKNLKAFINNEDLKNIVCFEKGY
>Mature_319_residues
SENASVVFFMKQTEERQELLKHSFANTSFYFPDKKGVPSDQILKTADVLVTFGDDITESLVSKASSLKWIHVMSAGIEGL
PLRLLHDRGVLVTNSRGIHAEPMSEHAIWAMLDYVKHATRYRMLQQNKQWDKSIKPKELTGMTAVFLGTGAIASKTAERA
NMFGMRTIGVNTDGRPQKHFEQTFSIEEWDKALRKADVLINILPYTEQTHGILNKEAFRQLKGHTVFINLGRGKSVVETD
LLDALKLKQIDHAYLDVFAEEPLPLDSPLWDDKAVTITPHVSAATSHYMKRALDIFMKNLKAFINNEDLKNIVCFEKGY

Specific function: Unknown

COG id: COG0111

COG function: function code HE; Phosphoglycerate dehydrogenase and related dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI6912396, Length=272, Percent_Identity=28.6764705882353, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI23308577, Length=269, Percent_Identity=26.0223048327138, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI87081824, Length=243, Percent_Identity=32.9218106995885, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87082289, Length=250, Percent_Identity=28.4, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17532191, Length=273, Percent_Identity=26.7399267399267, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28574286, Length=266, Percent_Identity=27.8195488721804, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24585516, Length=232, Percent_Identity=29.3103448275862, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI45552429, Length=234, Percent_Identity=27.3504273504274, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24585514, Length=234, Percent_Identity=27.3504273504274, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28574282, Length=234, Percent_Identity=27.3504273504274, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28574284, Length=234, Percent_Identity=27.3504273504274, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45551003, Length=234, Percent_Identity=27.3504273504274, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571528, Length=308, Percent_Identity=26.9480519480519, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI19921140, Length=241, Percent_Identity=25.3112033195021, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006140
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02826 2-Hacid_dh_C [H]

EC number: NA

Molecular weight: Translated: 36253; Mature: 36122

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENASVVFFMKQTEERQELLKHSFANTSFYFPDKKGVPSDQILKTADVLVTFGDDITES
CCCCCEEEEEECCCHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHEEEECCCHHHHH
LVSKASSLKWIHVMSAGIEGLPLRLLHDRGVLVTNSRGIHAEPMSEHAIWAMLDYVKHAT
HHHHHHCCEEEEEECCCCCCCCEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
RYRMLQQNKQWDKSIKPKELTGMTAVFLGTGAIASKTAERANMFGMRTIGVNTDGRPQKH
HHHHHHHCCHHHCCCCCCHHCCCEEEEEECCHHHHHHHHHHHHCEEEEECCCCCCCCHHH
FEQTFSIEEWDKALRKADVLINILPYTEQTHGILNKEAFRQLKGHTVFINLGRGKSVVET
HHHHCCHHHHHHHHHHHHHEEEEECCCCHHHCCCCHHHHHHHCCCEEEEECCCCCCHHHH
DLLDALKLKQIDHAYLDVFAEEPLPLDSPLWDDKAVTITPHVSAATSHYMKRALDIFMKN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LKAFINNEDLKNIVCFEKGY
HHHHHCCCCCCEEEEEECCC
>Mature Secondary Structure 
SENASVVFFMKQTEERQELLKHSFANTSFYFPDKKGVPSDQILKTADVLVTFGDDITES
CCCCEEEEEECCCHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHEEEECCCHHHHH
LVSKASSLKWIHVMSAGIEGLPLRLLHDRGVLVTNSRGIHAEPMSEHAIWAMLDYVKHAT
HHHHHHCCEEEEEECCCCCCCCEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
RYRMLQQNKQWDKSIKPKELTGMTAVFLGTGAIASKTAERANMFGMRTIGVNTDGRPQKH
HHHHHHHCCHHHCCCCCCHHCCCEEEEEECCHHHHHHHHHHHHCEEEEECCCCCCCCHHH
FEQTFSIEEWDKALRKADVLINILPYTEQTHGILNKEAFRQLKGHTVFINLGRGKSVVET
HHHHCCHHHHHHHHHHHHHEEEEECCCCHHHCCCCHHHHHHHCCCEEEEECCCCCCHHHH
DLLDALKLKQIDHAYLDVFAEEPLPLDSPLWDDKAVTITPHVSAATSHYMKRALDIFMKN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
LKAFINNEDLKNIVCFEKGY
HHHHHCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glycolate; NADP; hydroxypyruvate; NADPH [C]

Specific reaction: glycolate + NADP = NADPH + glyoxylate hydroxypyruvate + NADPH = glycerate + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]