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The map label for this gene is fruR [H]

Identifier: 56963041

GI number: 56963041

Start: 1391149

End: 1391913

Strand: Direct

Name: fruR [H]

Synonym: ABC1269

Alternate gene names: 56963041

Gene position: 1391149-1391913 (Clockwise)

Preceding gene: 56963040

Following gene: 56963042

Centisome position: 32.32

GC content: 42.88

Gene sequence:

>765_bases
ATGCTGACATTGGAAAGGCAAGAAAAAATCCTCGCCCTTCTCGCAAAGAACGAAGTGGTGAAAATTCAAGAATTAATTGT
AGAAACTGGTGCTTCTGAGTCTACGATACGACGAGACTTGACGGAGCTTGAGCAGAGAAATAAATTAAAGCGCATTCATG
GCGGTGCTACGTTATTGAAAAAAATGCGAGATGAGCCAACAATCGCGCAAAAAACGCTCAAAAACCGTCAGGAAAAAATA
AAAATTGCCAAGCAGGCTGCTGAACTCGTACAAGATGGAGATTGCCTGTTTTTAGATGCAGGGACAACTACTTATGAAAT
GATCCCCTTTTTGAAAGGCAAACAGATTGTAGTTGTGACAAATGGATTAACAAATATTGCCCATTTGCTTGAGGCCGAAA
TTGACACACATGTGCTTGGCGGGTATGCAAAAAAAGGCACACACGCTTTTGTTGGCCGAAACGCGTTGGAGGCGATTGAT
GCCTTTCGCTTTGACTTTGTGTTTCTTGGCACAAATGGCATTACCCCTAGTGATGGGTATACAACTCCTGATCTTGAAGA
AGCCTATATAAAAGTACAAGCGCTAAAACGAGGGCGGCAAACATATGTGTTAGCGGACCATACAAAATTTGGCGACGTTT
CGTTTTCAAAAATTGCCGATGTGGAGCGTGCCGCCATCATCACAAGCTCTTATACACGTGAAGAACAACCAGAGCTGTTT
TCACAACTTGCAGCTAAGACGACAATCAAGGTGGTAGAACAATGA

Upstream 100 bases:

>100_bases
CCGTTTGCCCGGTGCAACAAAAAGTTTACTTTTGGGTGAAAATGATTGAATTTGAATGTTTTTGGTTGTATACTAAGCAA
AGAGAGCTGAGGTGTGCGAA

Downstream 100 bases:

>100_bases
TTTACACAGTGACGTTAAATCCGGCAATGGATTACTTTGTCGCGCTCGATTCAATAAATAAGGGAGGTGTAAACCGGGCA
GCCCATGACTACAAAGCACC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLTLERQEKILALLAKNEVVKIQELIVETGASESTIRRDLTELEQRNKLKRIHGGATLLKKMRDEPTIAQKTLKNRQEKI
KIAKQAAELVQDGDCLFLDAGTTTYEMIPFLKGKQIVVVTNGLTNIAHLLEAEIDTHVLGGYAKKGTHAFVGRNALEAID
AFRFDFVFLGTNGITPSDGYTTPDLEEAYIKVQALKRGRQTYVLADHTKFGDVSFSKIADVERAAIITSSYTREEQPELF
SQLAAKTTIKVVEQ

Sequences:

>Translated_254_residues
MLTLERQEKILALLAKNEVVKIQELIVETGASESTIRRDLTELEQRNKLKRIHGGATLLKKMRDEPTIAQKTLKNRQEKI
KIAKQAAELVQDGDCLFLDAGTTTYEMIPFLKGKQIVVVTNGLTNIAHLLEAEIDTHVLGGYAKKGTHAFVGRNALEAID
AFRFDFVFLGTNGITPSDGYTTPDLEEAYIKVQALKRGRQTYVLADHTKFGDVSFSKIADVERAAIITSSYTREEQPELF
SQLAAKTTIKVVEQ
>Mature_254_residues
MLTLERQEKILALLAKNEVVKIQELIVETGASESTIRRDLTELEQRNKLKRIHGGATLLKKMRDEPTIAQKTLKNRQEKI
KIAKQAAELVQDGDCLFLDAGTTTYEMIPFLKGKQIVVVTNGLTNIAHLLEAEIDTHVLGGYAKKGTHAFVGRNALEAID
AFRFDFVFLGTNGITPSDGYTTPDLEEAYIKVQALKRGRQTYVLADHTKFGDVSFSKIADVERAAIITSSYTREEQPELF
SQLAAKTTIKVVEQ

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=229, Percent_Identity=32.3144104803493, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1789059, Length=222, Percent_Identity=35.5855855855856, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787540, Length=252, Percent_Identity=32.1428571428571, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789829, Length=236, Percent_Identity=30.0847457627119, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI226510968, Length=216, Percent_Identity=31.9444444444444, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790753, Length=230, Percent_Identity=26.5217391304348, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082344, Length=250, Percent_Identity=25.2, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790635, Length=251, Percent_Identity=26.2948207171315, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788069, Length=222, Percent_Identity=27.4774774774775, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787063, Length=246, Percent_Identity=28.0487804878049, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789170, Length=228, Percent_Identity=26.7543859649123, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28322; Mature: 28322

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLERQEKILALLAKNEVVKIQELIVETGASESTIRRDLTELEQRNKLKRIHGGATLLK
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH
KMRDEPTIAQKTLKNRQEKIKIAKQAAELVQDGDCLFLDAGTTTYEMIPFLKGKQIVVVT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCEEEEEE
NGLTNIAHLLEAEIDTHVLGGYAKKGTHAFVGRNALEAIDAFRFDFVFLGTNGITPSDGY
CCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHEEEEEEECCCCCCCCCC
TTPDLEEAYIKVQALKRGRQTYVLADHTKFGDVSFSKIADVERAAIITSSYTREEQPELF
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
SQLAAKTTIKVVEQ
HHHHHHHHHHHCCC
>Mature Secondary Structure
MLTLERQEKILALLAKNEVVKIQELIVETGASESTIRRDLTELEQRNKLKRIHGGATLLK
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHH
KMRDEPTIAQKTLKNRQEKIKIAKQAAELVQDGDCLFLDAGTTTYEMIPFLKGKQIVVVT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHCCCCCEEEEEE
NGLTNIAHLLEAEIDTHVLGGYAKKGTHAFVGRNALEAIDAFRFDFVFLGTNGITPSDGY
CCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHEEEEEEECCCCCCCCCC
TTPDLEEAYIKVQALKRGRQTYVLADHTKFGDVSFSKIADVERAAIITSSYTREEQPELF
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHH
SQLAAKTTIKVVEQ
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]