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The map label for this gene is cysW [H]

Identifier: 56963000

GI number: 56963000

Start: 1340325

End: 1341110

Strand: Direct

Name: cysW [H]

Synonym: ABC1228

Alternate gene names: 56963000

Gene position: 1340325-1341110 (Clockwise)

Preceding gene: 56962999

Following gene: 56963001

Centisome position: 31.14

GC content: 46.18

Gene sequence:

>786_bases
TTGTTTTTAGGTGCTTTTTTATTGCTCCCGCTTATCGTCATTTTTGCAGGGGCGTTTTCACAAGGGCTAACAGTGTTTTT
GGCAGCGATTAATGAGCCTGCTGCACGTTCAGCGATTCAGCTTACGCTGCTTGTGACCGTAATTACCGTGCCGTTGCAAC
TGTTGTTTGGCTTGTCGGCAGCGTGGCTATTGACAAAATTCCGTTTTCGAGGAAGGCAGTTGCTCATCACCTTAATTGAA
GTTCCTTTTGCTGTGTCACCCGTTATTGCGGGTCTAGTGTTTATTTTGTTATATGGTGTTCACGGCTTTTTTGGCGAATG
GCTTCAAGCACAAGGTTTCCAAATCATTTTCGCCGTCCCAGGCATTGTGCTGGCCACGATGTTTGTGACATTGCCTTTTA
TTGCAAGGGAACTCATTCCGTTAATGGAAGCACAAGGTTCTGAAGCGGAAGAAGCTTCGCTCACACTTGGGGCAGGCGGA
TGGCGGACATTTTGGCATGTCACGCTTCCCGCGATTAAATGGGGGCTTTTATACGGCGTCATTCTATGCAGTGCCAGGGC
GATAGGCGAATTTGGTGCTGTATCAGTTGTGTCTGGGCGCATTCGGGGACAAACAAATACAATGCCTTTACATATTGAAA
TTTTGTACAATGAATACCAATTTACTGCTTCTTTTGCAGTAGCGGCGCTCATGTCGCTATTTGCGCTCGTTACAATTGGC
GTTAAACAATGGGTAGAGTGGCGGCAAAAAAGGAGGAGCTATGACGATCTTACTGAACAAAATTGA

Upstream 100 bases:

>100_bases
CTTGCAGTGGCTATTGTCAAAACGATTAGGGCAAAAGGGGGCGTAAAAAATAAACAGCCGCAAAACGTGGAGTCAATTCC
TATTAATCATTGTCGCTTTT

Downstream 100 bases:

>100_bases
CAAACGCTTTGGGAACACCCATGTTTTAAAGCAAGTAGATTTACGGGTAGAGCAAGGTGAGTTGCTTGCTTTGCTCGGAC
CCTCGGGATCGGGGAAAACA

Product: sulfate ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MFLGAFLLLPLIVIFAGAFSQGLTVFLAAINEPAARSAIQLTLLVTVITVPLQLLFGLSAAWLLTKFRFRGRQLLITLIE
VPFAVSPVIAGLVFILLYGVHGFFGEWLQAQGFQIIFAVPGIVLATMFVTLPFIARELIPLMEAQGSEAEEASLTLGAGG
WRTFWHVTLPAIKWGLLYGVILCSARAIGEFGAVSVVSGRIRGQTNTMPLHIEILYNEYQFTASFAVAALMSLFALVTIG
VKQWVEWRQKRRSYDDLTEQN

Sequences:

>Translated_261_residues
MFLGAFLLLPLIVIFAGAFSQGLTVFLAAINEPAARSAIQLTLLVTVITVPLQLLFGLSAAWLLTKFRFRGRQLLITLIE
VPFAVSPVIAGLVFILLYGVHGFFGEWLQAQGFQIIFAVPGIVLATMFVTLPFIARELIPLMEAQGSEAEEASLTLGAGG
WRTFWHVTLPAIKWGLLYGVILCSARAIGEFGAVSVVSGRIRGQTNTMPLHIEILYNEYQFTASFAVAALMSLFALVTIG
VKQWVEWRQKRRSYDDLTEQN
>Mature_261_residues
MFLGAFLLLPLIVIFAGAFSQGLTVFLAAINEPAARSAIQLTLLVTVITVPLQLLFGLSAAWLLTKFRFRGRQLLITLIE
VPFAVSPVIAGLVFILLYGVHGFFGEWLQAQGFQIIFAVPGIVLATMFVTLPFIARELIPLMEAQGSEAEEASLTLGAGG
WRTFWHVTLPAIKWGLLYGVILCSARAIGEFGAVSVVSGRIRGQTNTMPLHIEILYNEYQFTASFAVAALMSLFALVTIG
VKQWVEWRQKRRSYDDLTEQN

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=265, Percent_Identity=51.3207547169811, Blast_Score=274, Evalue=5e-75,
Organism=Escherichia coli, GI1788764, Length=202, Percent_Identity=38.1188118811881, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1786980, Length=218, Percent_Identity=31.651376146789, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28737; Mature: 28737

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLGAFLLLPLIVIFAGAFSQGLTVFLAAINEPAARSAIQLTLLVTVITVPLQLLFGLSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWLLTKFRFRGRQLLITLIEVPFAVSPVIAGLVFILLYGVHGFFGEWLQAQGFQIIFAVP
HHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHH
GIVLATMFVTLPFIARELIPLMEAQGSEAEEASLTLGAGGWRTFWHVTLPAIKWGLLYGV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
ILCSARAIGEFGAVSVVSGRIRGQTNTMPLHIEILYNEYQFTASFAVAALMSLFALVTIG
HHHHHHHHCCCCCHHHHHCHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
VKQWVEWRQKRRSYDDLTEQN
HHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MFLGAFLLLPLIVIFAGAFSQGLTVFLAAINEPAARSAIQLTLLVTVITVPLQLLFGLSA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWLLTKFRFRGRQLLITLIEVPFAVSPVIAGLVFILLYGVHGFFGEWLQAQGFQIIFAVP
HHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHH
GIVLATMFVTLPFIARELIPLMEAQGSEAEEASLTLGAGGWRTFWHVTLPAIKWGLLYGV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
ILCSARAIGEFGAVSVVSGRIRGQTNTMPLHIEILYNEYQFTASFAVAALMSLFALVTIG
HHHHHHHHCCCCCHHHHHCHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
VKQWVEWRQKRRSYDDLTEQN
HHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]