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The map label for this gene is cysU [H]

Identifier: 56962999

GI number: 56962999

Start: 1339446

End: 1340270

Strand: Direct

Name: cysU [H]

Synonym: ABC1227

Alternate gene names: 56962999

Gene position: 1339446-1340270 (Clockwise)

Preceding gene: 56962998

Following gene: 56963000

Centisome position: 31.12

GC content: 48.61

Gene sequence:

>825_bases
ATGAAACGGATATTGCCGGGATTTGGCTTAAGCTTTGGATTTACAATGCTCTATTTGAGCTTTGTGGTGCTCATTCCATT
AGCTGCATTGCTGTTGTTTACTGTCCACAACGGCTGGGAAACGTTTTGGAATGCCGTAAATGACCCCCGCGTGTTCGCCG
CATTTCGATTAAGCTTCTCGGCTGCCTTGATGGCGGCATTCATCAATGGCGTGTTTGGGCTATTAGTGGCATGGGTGATG
GCACGCTACTCGTTTTTCGGGAAACGATTGATGGATGGCATGATCGATTTGCCGTTTGCTTTACCGACAGCCGTAGCGGG
CATCGCCTTAACAAGCCTCTATACGGAAAATGGCTGGATTGGGTCATTGCTTGCGCCTTTAGGCATAGAGGTTGCCTTTA
CGCCGATTGGCGTCACGATCGCGTTAACTTTTATTGGCTTGCCATTTGTTGTCCGGATGGTTGAACCTGTGCTTAAAAAC
CTCGACAAGGAAGTAGAAGAAGCGTCCGCTCTTTTAGGAGCAACGCCAGTAAAAACATTTTTAACAGTCATTTTTCCGGT
GTTGGCCCCGGCACTATTAGCCGGTATGGCGCTTGCCTTTGCCAGGGCGCTAGGTGAATACGGTTCAGTTGTGTTTATTG
CTGGGAATATGCCGATGCAAACAGAAATAGTGCCGCTTTTGATTATGACGAAGCTTGAGCAATTTGACTACGGGGGCGCT
ACCGCGATTGCGGTCGTTATGCTAGTCGTGTCATTCTTGCTGTTGCTGCTTACCAATGGCTTGCAGTGGCTATTGTCAAA
ACGATTAGGGCAAAAGGGGGCGTAA

Upstream 100 bases:

>100_bases
ATTTGACCAGATATACCAGCCCAATTAAGGTGAGCGTTGCCGCCTTGATGTTCCATAAGCAGCATGGAACAACTAGAAAA
ACAGACGATAGGAGTTTGCT

Downstream 100 bases:

>100_bases
AAAATAAACAGCCGCAAAACGTGGAGTCAATTCCTATTAATCATTGTCGCTTTTTTGTTTTTAGGTGCTTTTTTATTGCT
CCCGCTTATCGTCATTTTTG

Product: sulfate ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKRILPGFGLSFGFTMLYLSFVVLIPLAALLLFTVHNGWETFWNAVNDPRVFAAFRLSFSAALMAAFINGVFGLLVAWVM
ARYSFFGKRLMDGMIDLPFALPTAVAGIALTSLYTENGWIGSLLAPLGIEVAFTPIGVTIALTFIGLPFVVRMVEPVLKN
LDKEVEEASALLGATPVKTFLTVIFPVLAPALLAGMALAFARALGEYGSVVFIAGNMPMQTEIVPLLIMTKLEQFDYGGA
TAIAVVMLVVSFLLLLLTNGLQWLLSKRLGQKGA

Sequences:

>Translated_274_residues
MKRILPGFGLSFGFTMLYLSFVVLIPLAALLLFTVHNGWETFWNAVNDPRVFAAFRLSFSAALMAAFINGVFGLLVAWVM
ARYSFFGKRLMDGMIDLPFALPTAVAGIALTSLYTENGWIGSLLAPLGIEVAFTPIGVTIALTFIGLPFVVRMVEPVLKN
LDKEVEEASALLGATPVKTFLTVIFPVLAPALLAGMALAFARALGEYGSVVFIAGNMPMQTEIVPLLIMTKLEQFDYGGA
TAIAVVMLVVSFLLLLLTNGLQWLLSKRLGQKGA
>Mature_274_residues
MKRILPGFGLSFGFTMLYLSFVVLIPLAALLLFTVHNGWETFWNAVNDPRVFAAFRLSFSAALMAAFINGVFGLLVAWVM
ARYSFFGKRLMDGMIDLPFALPTAVAGIALTSLYTENGWIGSLLAPLGIEVAFTPIGVTIALTFIGLPFVVRMVEPVLKN
LDKEVEEASALLGATPVKTFLTVIFPVLAPALLAGMALAFARALGEYGSVVFIAGNMPMQTEIVPLLIMTKLEQFDYGGA
TAIAVVMLVVSFLLLLLTNGLQWLLSKRLGQKGA

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=268, Percent_Identity=47.0149253731343, Blast_Score=236, Evalue=8e-64,
Organism=Escherichia coli, GI87082099, Length=263, Percent_Identity=31.9391634980989, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786980, Length=228, Percent_Identity=30.2631578947368, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787369, Length=247, Percent_Identity=26.7206477732794, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786254, Length=231, Percent_Identity=26.4069264069264, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787080, Length=240, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787368, Length=225, Percent_Identity=28, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787081, Length=229, Percent_Identity=28.3842794759825, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011865
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29559; Mature: 29559

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILPGFGLSFGFTMLYLSFVVLIPLAALLLFTVHNGWETFWNAVNDPRVFAAFRLSFS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHH
AALMAAFINGVFGLLVAWVMARYSFFGKRLMDGMIDLPFALPTAVAGIALTSLYTENGWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
GSLLAPLGIEVAFTPIGVTIALTFIGLPFVVRMVEPVLKNLDKEVEEASALLGATPVKTF
HHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LTVIFPVLAPALLAGMALAFARALGEYGSVVFIAGNMPMQTEIVPLLIMTKLEQFDYGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCH
TAIAVVMLVVSFLLLLLTNGLQWLLSKRLGQKGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRILPGFGLSFGFTMLYLSFVVLIPLAALLLFTVHNGWETFWNAVNDPRVFAAFRLSFS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHH
AALMAAFINGVFGLLVAWVMARYSFFGKRLMDGMIDLPFALPTAVAGIALTSLYTENGWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCH
GSLLAPLGIEVAFTPIGVTIALTFIGLPFVVRMVEPVLKNLDKEVEEASALLGATPVKTF
HHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LTVIFPVLAPALLAGMALAFARALGEYGSVVFIAGNMPMQTEIVPLLIMTKLEQFDYGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCH
TAIAVVMLVVSFLLLLLTNGLQWLLSKRLGQKGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2188958; 9205837; 9278503; 2188959 [H]