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The map label for this gene is argB

Identifier: 55981919

GI number: 55981919

Start: 1827402

End: 1828151

Strand: Reverse

Name: argB

Synonym: TTHA1950

Alternate gene names: 55981919

Gene position: 1828151-1827402 (Counterclockwise)

Preceding gene: 55981920

Following gene: 55981912

Centisome position: 98.83

GC content: 71.2

Gene sequence:

>750_bases
TTGAGTGAGGCCCTTTTGGTGAAGGTGGGGGGAAGCCTGAGGGGGGCGGAGGCCCTGCTGGAGGAGCTCGCCGCCTACCC
CGGCCCCCTGGTCCTGGTCCACGGGGGCGGCCCCGAGATCGGGGAGTGGCTGAAGCGCCTGGGGTACGAGAGCCGCTTCG
TGGGGGGGCTGAGGGTCACCCCCCCGGAGCAGTTGGAGGTGGTGGAGATGGCCCTCTACCTCACGGGGAAGCGCCTGGCC
TGGGGGCTTTCCCGAAGGGGAAGGAAGGCCCTCGCCCTCTCGGGGCGGGACGCCCTCTGCCTAAGGGGGAGGGCCCTTCC
GGAGCTCGGCCGCGTGGGGGAGGTGGTGGGGGTGGAGGTGGGCCTCCTCCTGGACCTCCTAGAGAAGGGCTACACCCCCC
TTCTCGCACCCATCGCCCTGGACGAGGAAGGTCCCCTAAACGTCAACGCCGACACCGCCGCGGGGGCCGTGGCCGGGGCC
TTGGGGTGGCCCGCGGTCTTCCTCACCGACGTGGAAGGGGTCTACCGGAACCCCAAGGACCCGAAGACCCGCTTCCCCCG
GCTCACCCCAAAAGAGGTGGAGGCCCTGAAGGAGGAGGGCGTGATCCAAGGGGGCATGATCCCCAAGGTGGAGGCGGCCC
TCGCCGCCCTCAGGGCGGGGGCCCCCTGGGCGGCCGTGGCCAAGGGGGAGAGGGGGGTCTTGCGCAGGCTTCTCTCAGGG
GAAGGAGGCACCCTCTTTAGCCCCTCCTAG

Upstream 100 bases:

>100_bases
GCCAACTTCTTCGGCCTCCACCCGGACCACGCCCTCCTGGGCTTTTTGGACCTCCTGGAGGCCGAGGAGGAGGGGGGTTT
GCCCGAGGAGGTGGTCTACC

Downstream 100 bases:

>100_bases
CCCCGGGGTAGCTCCTCAAAAACGTTGGTCCAGACGTTGAGTACCTGCCCTCCCCCGTTGGTTTGGCCCGTTTCTATGAC
CTTGACCACCGTTAGGGAGC

Product: N-acetylglutamate kinase ArgB-2

Products: NA

Alternate protein names: N-acetyl-L-glutamate/N-acetyl-L-aminoadipate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSEALLVKVGGSLRGAEALLEELAAYPGPLVLVHGGGPEIGEWLKRLGYESRFVGGLRVTPPEQLEVVEMALYLTGKRLA
WGLSRRGRKALALSGRDALCLRGRALPELGRVGEVVGVEVGLLLDLLEKGYTPLLAPIALDEEGPLNVNADTAAGAVAGA
LGWPAVFLTDVEGVYRNPKDPKTRFPRLTPKEVEALKEEGVIQGGMIPKVEAALAALRAGAPWAAVAKGERGVLRRLLSG
EGGTLFSPS

Sequences:

>Translated_249_residues
MSEALLVKVGGSLRGAEALLEELAAYPGPLVLVHGGGPEIGEWLKRLGYESRFVGGLRVTPPEQLEVVEMALYLTGKRLA
WGLSRRGRKALALSGRDALCLRGRALPELGRVGEVVGVEVGLLLDLLEKGYTPLLAPIALDEEGPLNVNADTAAGAVAGA
LGWPAVFLTDVEGVYRNPKDPKTRFPRLTPKEVEALKEEGVIQGGMIPKVEAALAALRAGAPWAAVAKGERGVLRRLLSG
EGGTLFSPS
>Mature_248_residues
SEALLVKVGGSLRGAEALLEELAAYPGPLVLVHGGGPEIGEWLKRLGYESRFVGGLRVTPPEQLEVVEMALYLTGKRLAW
GLSRRGRKALALSGRDALCLRGRALPELGRVGEVVGVEVGLLLDLLEKGYTPLLAPIALDEEGPLNVNADTAAGAVAGAL
GWPAVFLTDVEGVYRNPKDPKTRFPRLTPKEVEALKEEGVIQGGMIPKVEAALAALRAGAPWAAVAKGERGVLRRLLSGE
GGTLFSPS

Specific function: Involved in both the arginine and lysine biosynthetic pathways

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=232, Percent_Identity=37.9310344827586, Blast_Score=101, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_THET8 (Q5SGY0)

Other databases:

- EMBL:   AP008226
- RefSeq:   YP_145216.1
- HSSP:   Q9HTN2
- ProteinModelPortal:   Q5SGY0
- SMR:   Q5SGY0
- STRING:   Q5SGY0
- GeneID:   3168085
- GenomeReviews:   AP008226_GR
- KEGG:   ttj:TTHA1950
- NMPDR:   fig|300852.3.peg.1696
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- ProtClustDB:   CLSK445594
- BioCyc:   TTHE300852:TTHA1950-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 26225; Mature: 26094

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: BINDING 58-58 BINDING 147-147

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEALLVKVGGSLRGAEALLEELAAYPGPLVLVHGGGPEIGEWLKRLGYESRFVGGLRVT
CCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCEECC
PPEQLEVVEMALYLTGKRLAWGLSRRGRKALALSGRDALCLRGRALPELGRVGEVVGVEV
CHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHH
GLLLDLLEKGYTPLLAPIALDEEGPLNVNADTAAGAVAGALGWPAVFLTDVEGVYRNPKD
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEECCHHHHCCCCC
PKTRFPRLTPKEVEALKEEGVIQGGMIPKVEAALAALRAGAPWAAVAKGERGVLRRLLSG
CHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHCC
EGGTLFSPS
CCCEEECCC
>Mature Secondary Structure 
SEALLVKVGGSLRGAEALLEELAAYPGPLVLVHGGGPEIGEWLKRLGYESRFVGGLRVT
CCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCEECC
PPEQLEVVEMALYLTGKRLAWGLSRRGRKALALSGRDALCLRGRALPELGRVGEVVGVEV
CHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHH
GLLLDLLEKGYTPLLAPIALDEEGPLNVNADTAAGAVAGALGWPAVFLTDVEGVYRNPKD
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEECCHHHHCCCCC
PKTRFPRLTPKEVEALKEEGVIQGGMIPKVEAALAALRAGAPWAAVAKGERGVLRRLLSG
CHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHCC
EGGTLFSPS
CCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA