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The map label for this gene is trxB [H]

Identifier: 55981889

GI number: 55981889

Start: 1800404

End: 1801381

Strand: Reverse

Name: trxB [H]

Synonym: TTHA1920

Alternate gene names: 55981889

Gene position: 1801381-1800404 (Counterclockwise)

Preceding gene: 55981892

Following gene: 55981888

Centisome position: 97.39

GC content: 68.51

Gene sequence:

>978_bases
ATGGAGTTCAACCTGAGCGCACTAGGGAGCGCCCCCGCCGCGGAGGAAACCTACGATGTGGTCATCATCGGCGGGGGGCC
CGCGGGGCTTACCGCCGGGATCTACGCCGGCCGGGCCCAGCTCAAGACGGTCATCGTGGAGAAGGGGCTTCCCGGGGGGC
AGATCGCCCAGACGGACGAGGTGGAGAACTACCCGGGCTTCCCCGAGGGCATCTCCGGGCCGGAGCTCGCGAGCCGCATG
GTGCGGCAGGCGGAGAAGTTCGGGGCCCGGATCGTCATGGACGAGGTCCTGGGCCTGGAGAAGGCCGAGGGGGGCTACCT
GGTCCGGGGCTACGAGCGGAACTACCGCGCCCGGGCGGTGATCGTGGCCACGGGGGCGAACCCGAGGCGGCTTGGGGTCC
CCGGGGAGGACAAGTTTTACGGCCGGGGGGTTTCCACCTGCGCCACCTGCGACGGCTTCTTCTACCGGGACAAGGAGGTG
GTCGTGGTGGGTGGGGGGGACGCCGCCGTGGAGGAGGGGATCTTCCTCACCAAGTTCGCCCGAAAAGTGACCCTGGTCCA
CCGCCGGGACGAGCTTAGGGCCAACAAGGTGGCCCAGAAGCGGGCCTTCCAGAACCCCAAGATGCACTTCCTCTTCTCCC
ACGTGGTCACCGAGATCCTGGGGGAGGACCAGGTGACGGGGGTGCGGCTTAAGAACCTAAAGACGGGGGAGGAGTACGTC
TACCCCACGGACGGCGTCTTCGTCTTCATCGGCCACGAGCCCAACACCGCTTTCCTCAAGGGGGTGGTGGAGCTCCGGCC
CGACGGGTACATTGCCGTGCGGGACGAGGTCTTCACCTCGGAGCCCGGCATCTTCGCCGCCGGGGACGTGGCCGACCCCA
TCTACCGCCAGCTCACCACGAGCGTGGGGGCGGGCACCCGCGCCGCCATGATGGCCGAGCGCTACCTGGCGGAGGAGGCG
GAAAAGGTCAAGGGCTAG

Upstream 100 bases:

>100_bases
TTTTCTTGACACCCTTCCCCCTTACCCCTCAAAATGGGGCGAGGCATACCCCCTATAGGTATGTGAGGGGGTAAACTGGC
GTCCAAGGAGGAGGGAAAGA

Downstream 100 bases:

>100_bases
GGCGGGCGTGGCGCGCCTTTGGGCGCTTCTCGTGGCCTGGGGCCTGGGCCTCGCCCAGCTCCTCTACCTTCCCCTGGACG
ACCGCCCCCCCAACCTCGCC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MEFNLSALGSAPAAEETYDVVIIGGGPAGLTAGIYAGRAQLKTVIVEKGLPGGQIAQTDEVENYPGFPEGISGPELASRM
VRQAEKFGARIVMDEVLGLEKAEGGYLVRGYERNYRARAVIVATGANPRRLGVPGEDKFYGRGVSTCATCDGFFYRDKEV
VVVGGGDAAVEEGIFLTKFARKVTLVHRRDELRANKVAQKRAFQNPKMHFLFSHVVTEILGEDQVTGVRLKNLKTGEEYV
YPTDGVFVFIGHEPNTAFLKGVVELRPDGYIAVRDEVFTSEPGIFAAGDVADPIYRQLTTSVGAGTRAAMMAERYLAEEA
EKVKG

Sequences:

>Translated_325_residues
MEFNLSALGSAPAAEETYDVVIIGGGPAGLTAGIYAGRAQLKTVIVEKGLPGGQIAQTDEVENYPGFPEGISGPELASRM
VRQAEKFGARIVMDEVLGLEKAEGGYLVRGYERNYRARAVIVATGANPRRLGVPGEDKFYGRGVSTCATCDGFFYRDKEV
VVVGGGDAAVEEGIFLTKFARKVTLVHRRDELRANKVAQKRAFQNPKMHFLFSHVVTEILGEDQVTGVRLKNLKTGEEYV
YPTDGVFVFIGHEPNTAFLKGVVELRPDGYIAVRDEVFTSEPGIFAAGDVADPIYRQLTTSVGAGTRAAMMAERYLAEEA
EKVKG
>Mature_325_residues
MEFNLSALGSAPAAEETYDVVIIGGGPAGLTAGIYAGRAQLKTVIVEKGLPGGQIAQTDEVENYPGFPEGISGPELASRM
VRQAEKFGARIVMDEVLGLEKAEGGYLVRGYERNYRARAVIVATGANPRRLGVPGEDKFYGRGVSTCATCDGFFYRDKEV
VVVGGGDAAVEEGIFLTKFARKVTLVHRRDELRANKVAQKRAFQNPKMHFLFSHVVTEILGEDQVTGVRLKNLKTGEEYV
YPTDGVFVFIGHEPNTAFLKGVVELRPDGYIAVRDEVFTSEPGIFAAGDVADPIYRQLTTSVGAGTRAAMMAERYLAEEA
EKVKG

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=307, Percent_Identity=44.9511400651466, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=32.3809523809524, Blast_Score=148, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6320560, Length=311, Percent_Identity=42.7652733118971, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6321898, Length=316, Percent_Identity=41.7721518987342, Blast_Score=237, Evalue=2e-63,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35178; Mature: 35178

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFNLSALGSAPAAEETYDVVIIGGGPAGLTAGIYAGRAQLKTVIVEKGLPGGQIAQTDE
CCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCHHHHEEEEEECCCCCCCCCCCCC
VENYPGFPEGISGPELASRMVRQAEKFGARIVMDEVLGLEKAEGGYLVRGYERNYRARAV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHCCEECCCCEEEEECCCCCEEEEE
IVATGANPRRLGVPGEDKFYGRGVSTCATCDGFFYRDKEVVVVGGGDAAVEEGIFLTKFA
EEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEECCEEEEECCCCHHHHCCCHHHHHH
RKVTLVHRRDELRANKVAQKRAFQNPKMHFLFSHVVTEILGEDQVTGVRLKNLKTGEEYV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEE
YPTDGVFVFIGHEPNTAFLKGVVELRPDGYIAVRDEVFTSEPGIFAAGDVADPIYRQLTT
ECCCCEEEEEECCCCHHHHHEEEEECCCCEEEEECCEECCCCCEEEECCCCHHHHHHHHH
SVGAGTRAAMMAERYLAEEAEKVKG
HCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFNLSALGSAPAAEETYDVVIIGGGPAGLTAGIYAGRAQLKTVIVEKGLPGGQIAQTDE
CCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCHHHHEEEEEECCCCCCCCCCCCC
VENYPGFPEGISGPELASRMVRQAEKFGARIVMDEVLGLEKAEGGYLVRGYERNYRARAV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHCCEECCCCEEEEECCCCCEEEEE
IVATGANPRRLGVPGEDKFYGRGVSTCATCDGFFYRDKEVVVVGGGDAAVEEGIFLTKFA
EEEECCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEECCEEEEECCCCHHHHCCCHHHHHH
RKVTLVHRRDELRANKVAQKRAFQNPKMHFLFSHVVTEILGEDQVTGVRLKNLKTGEEYV
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEE
YPTDGVFVFIGHEPNTAFLKGVVELRPDGYIAVRDEVFTSEPGIFAAGDVADPIYRQLTT
ECCCCEEEEEECCCCHHHHHEEEEECCCCEEEEECCEECCCCCEEEECCCCHHHHHHHHH
SVGAGTRAAMMAERYLAEEAEKVKG
HCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9795994 [H]