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The map label for this gene is macB [H]

Identifier: 55981802

GI number: 55981802

Start: 1715110

End: 1716252

Strand: Direct

Name: macB [H]

Synonym: TTHA1833

Alternate gene names: 55981802

Gene position: 1715110-1716252 (Clockwise)

Preceding gene: 55981801

Following gene: 55981803

Centisome position: 92.72

GC content: 70.69

Gene sequence:

>1143_bases
ATGGAGCTTTTCCTCCTCGTCCTCCGCAACCTCCTGGCCCGGCCCGTCCGGAGCCTCCTCACCCTGCTCGGGGTCCTGGT
GGCCACGGCGAGCATGGTCCTCTTCCTCTCCTTCGGGGAGGGCCTTAGGCGGGCCCTCTTCCAGGAGCTCTCCCGGGTGG
GCCCCGCCATCCAGGTGGTGCCGGAAGGGGCGGAGGGCTTCGTCTTCGGCGCCCTCCCCGAGATCCCCCCCGAGACCCTC
AAGGCCCTGGAGGAGGCAGGAAAGGCCCTGGGGGTGCGGGCGGTGGTCCCCACCCTCTTCCTCACCCGGGGGGGCTTTGA
CCCCAGCACCAGCTTCCTCTTCCAGGGCCTGCCGGAAGGAACCCCTCCGGACCTCCTCTACCCGGGGCTCAAGGCCAAGG
AAGGCCGCCTCACCCCCTCGGAGAAAGGGGCCGTGGTGGGGGCCAAGGTGGCGGAGCGGAGCGGCCTCGCCCTGGGAAGC
GTCCTGAGGCTCACCCCCAGGCTGGAGCTTAGGGTGGAGGGGGTCCTGGAGGCGACGGGAGGCCTCGCGGACAACCTGAT
CTTCGTCCCCTTGAGGGCGATCCAGGAGGCCTTGGGCACGGAGAACGTGACCGCGGTGCTCGTGGCCCTAAGCCCCGGCC
AGAAGGCGGAAGCGGTGGCCCGGGCCCTGGAGGAGGCGGTCCCCGGGGTGAAGGCCCAGACCACGAGCGAGGTGATGCGC
TTCGCCGAACGCGCCCTAAGGATCAGCGACCTGGTGCGCTTCGGCATCAGCCTGGTGGCCCTGGTGGTGGGGGGGCTTCT
CGTGGCCAACACCGTGACCATGTCCGTGTACGAGCGGGTGCGGGAGTTCGGGGTCATGCGCGCCCTGGGGGCGAGGCGGG
GGTTCATCTTCCGCCTCGTCCTTCTGGAGGCCCTCCTCATCGCCCTCCTTGGCGGGGCCTTGGGGCTTGGGCTTGGGGCC
CTCGGCGCCTTCGCCATCAACCTCTACACCTTGGACCAGGTGGGCCTGGCCCTCTCGGCGGTGACGGGAAGGCTCGCCCT
CTTCGCCCTGGGGGTGGCCCTCGGCCTCGGGCTTACCGCCGGGCTTCTTCCCGCCTACCACGCAAGCCGCATCCCCGTGG
TGGAGGCTTTGGGGAGGGTGTAG

Upstream 100 bases:

>100_bases
ACCCCAGGGCGTACCTGGAGGCGGTGGAAACCCGTTTCGTGGAACGCCTTCTGTAGGCCAGGCCACGCCCCTGGCCCCGC
CTTGGGGTAGCCTCGGAGGG

Downstream 100 bases:

>100_bases
ATGACCATCCGGGCGGAAAACCTCACCAAGCGCTACCGGCAAGGGGAAAAAGAGGTGGTGGCCCTTCTGAGCTTCACCTA
CGCTTTCCCCCCGGGGGCCA

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MELFLLVLRNLLARPVRSLLTLLGVLVATASMVLFLSFGEGLRRALFQELSRVGPAIQVVPEGAEGFVFGALPEIPPETL
KALEEAGKALGVRAVVPTLFLTRGGFDPSTSFLFQGLPEGTPPDLLYPGLKAKEGRLTPSEKGAVVGAKVAERSGLALGS
VLRLTPRLELRVEGVLEATGGLADNLIFVPLRAIQEALGTENVTAVLVALSPGQKAEAVARALEEAVPGVKAQTTSEVMR
FAERALRISDLVRFGISLVALVVGGLLVANTVTMSVYERVREFGVMRALGARRGFIFRLVLLEALLIALLGGALGLGLGA
LGAFAINLYTLDQVGLALSAVTGRLALFALGVALGLGLTAGLLPAYHASRIPVVEALGRV

Sequences:

>Translated_380_residues
MELFLLVLRNLLARPVRSLLTLLGVLVATASMVLFLSFGEGLRRALFQELSRVGPAIQVVPEGAEGFVFGALPEIPPETL
KALEEAGKALGVRAVVPTLFLTRGGFDPSTSFLFQGLPEGTPPDLLYPGLKAKEGRLTPSEKGAVVGAKVAERSGLALGS
VLRLTPRLELRVEGVLEATGGLADNLIFVPLRAIQEALGTENVTAVLVALSPGQKAEAVARALEEAVPGVKAQTTSEVMR
FAERALRISDLVRFGISLVALVVGGLLVANTVTMSVYERVREFGVMRALGARRGFIFRLVLLEALLIALLGGALGLGLGA
LGAFAINLYTLDQVGLALSAVTGRLALFALGVALGLGLTAGLLPAYHASRIPVVEALGRV
>Mature_380_residues
MELFLLVLRNLLARPVRSLLTLLGVLVATASMVLFLSFGEGLRRALFQELSRVGPAIQVVPEGAEGFVFGALPEIPPETL
KALEEAGKALGVRAVVPTLFLTRGGFDPSTSFLFQGLPEGTPPDLLYPGLKAKEGRLTPSEKGAVVGAKVAERSGLALGS
VLRLTPRLELRVEGVLEATGGLADNLIFVPLRAIQEALGTENVTAVLVALSPGQKAEAVARALEEAVPGVKAQTTSEVMR
FAERALRISDLVRFGISLVALVVGGLLVANTVTMSVYERVREFGVMRALGARRGFIFRLVLLEALLIALLGGALGLGLGA
LGAFAINLYTLDQVGLALSAVTGRLALFALGVALGLGLTAGLLPAYHASRIPVVEALGRV

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=410, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 39750; Mature: 39750

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELFLLVLRNLLARPVRSLLTLLGVLVATASMVLFLSFGEGLRRALFQELSRVGPAIQVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
PEGAEGFVFGALPEIPPETLKALEEAGKALGVRAVVPTLFLTRGGFDPSTSFLFQGLPEG
ECCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
TPPDLLYPGLKAKEGRLTPSEKGAVVGAKVAERSGLALGSVLRLTPRLELRVEGVLEATG
CCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCC
GLADNLIFVPLRAIQEALGTENVTAVLVALSPGQKAEAVARALEEAVPGVKAQTTSEVMR
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
FAERALRISDLVRFGISLVALVVGGLLVANTVTMSVYERVREFGVMRALGARRGFIFRLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLEALLIALLGGALGLGLGALGAFAINLYTLDQVGLALSAVTGRLALFALGVALGLGLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLPAYHASRIPVVEALGRV
HHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure
MELFLLVLRNLLARPVRSLLTLLGVLVATASMVLFLSFGEGLRRALFQELSRVGPAIQVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
PEGAEGFVFGALPEIPPETLKALEEAGKALGVRAVVPTLFLTRGGFDPSTSFLFQGLPEG
ECCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
TPPDLLYPGLKAKEGRLTPSEKGAVVGAKVAERSGLALGSVLRLTPRLELRVEGVLEATG
CCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHCC
GLADNLIFVPLRAIQEALGTENVTAVLVALSPGQKAEAVARALEEAVPGVKAQTTSEVMR
CCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
FAERALRISDLVRFGISLVALVVGGLLVANTVTMSVYERVREFGVMRALGARRGFIFRLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLEALLIALLGGALGLGLGALGAFAINLYTLDQVGLALSAVTGRLALFALGVALGLGLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLPAYHASRIPVVEALGRV
HHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA