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The map label for this gene is ag45 [H]

Identifier: 55981767

GI number: 55981767

Start: 1679542

End: 1680732

Strand: Reverse

Name: ag45 [H]

Synonym: TTHA1798

Alternate gene names: 55981767

Gene position: 1680732-1679542 (Counterclockwise)

Preceding gene: 55981768

Following gene: 55981762

Centisome position: 90.86

GC content: 70.95

Gene sequence:

>1191_bases
ATGGCGCTTCGGGAAACCCTTAGCCTCCTCGTCCTCCTCCTCGCCTACCTGGGCCTCGCCCTGGGGGGGCTTCCCGGCTA
CCGGATGAACCGGGCGGGGGTGGCCCTGGTGGGGGCAAGCCTCCTCGTGCTCCTCGGCGCCTTGGACCTCGAGGAGGCCT
GGCGGGCCCTGGACCCCTCCACCCTGGTCTTCCTCTTCGGGGTCATGGTCCTGAACGCCCACCTGGGCTACGCGGGCTTC
TTCGGCTGGGTGGCCGAGGGGCTTTGGAAGAGGGCCAGGACCCCCTTCGCCCTCCTCGTCCTCCTCAGCCTGGGCTCGGG
CCTCCTTTCCGCCCTCTTCCTCAACGACACCATGGCCCTCCTCCTCACCCCCCTCGTCCTCCGCCTCGCCCGGGGCCTGG
GCCTGAACCCCGTGCCTTACCTCCTCGCCCTCATGGCGGGGGTGAACACGGGAAGCCTCATGACCCCCACGGGAAACCCC
CAGAACATCCTGGTGGCGAGCCTCTCGGGGATGGCCTACCTGGACTTCCTCCGGGCCCTTTTCCCCGTGGCCTTCCTGGG
CCTCGCCCTGCAGGTGGGGCTCCTCGCCCTCCTCTACCCCGAGGCCCGCTCCCTAAGGCCCCTTCCGCCCCCTCCCCCTT
TGCGCTACCGGCTCCACCCCGGGCTTCTCCGCAAAGGGCTTCTCGTGGCCTCGGGGCTCCTCCTCGCCTTCCTCCTCGGC
TACCCCATGGCCCAGGGGGCCTTGGTGGCGGCGGGGCTTCTCCTCTTCACCCGGAGGCTCCGCTCGGAGCGGTACTTCAT
GCGGGTGGACTGGGAGCTTCTGGTGATGTTCGGCGGGCTCTTCGTCCTCACCGAAGGGGTGCGCCGCCTGGGGCTCGCCG
AGGCCCTTTTGCCCCTCGCCTCTAGCCCCCTCGGGCTCCTCCTCGCCGCCACCCTCCTCTCCCTCCTCATCTCCAACGTG
CCCGCGGTCCTCCTCCTCGCCCCCCTGGCCAAGACCCCGGAGGAGTGGCTCCTCCTCGCCGGGGGGAGCACCCTGGCGGG
CAACCTCACCCTGCTCGCCAGCGTGGCGAACCTCATCGTGGCCGAGGGGGCGGGACGGGAGGGGGTGCGGGTGGGCCTCC
TGGAGCACCTCCGCTTCGGGCTTCCCCTCACCCTCTTCTCCCTGGCCCTCCTCTACCTGGGGCTAGCCTAG

Upstream 100 bases:

>100_bases
AACCGCAGGCTTCCCGATGGCGCCTTCCGGGACGACGTGGTCTACAGCGTCCTCAAGGAGGAGTGGCCGGGGGTGAAGGC
GAGGCTAGAGGCCAGGCTCT

Downstream 100 bases:

>100_bases
CCGGGCCTCGAGCCAGCCCCCGAGGGCCAGGACCTTCCCGTCCTCCCCGTACGCCCCCACCACCTGGAGCCCCACCGGCA
TCCCCTCCACCTTGGCGAAG

Product: transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MALRETLSLLVLLLAYLGLALGGLPGYRMNRAGVALVGASLLVLLGALDLEEAWRALDPSTLVFLFGVMVLNAHLGYAGF
FGWVAEGLWKRARTPFALLVLLSLGSGLLSALFLNDTMALLLTPLVLRLARGLGLNPVPYLLALMAGVNTGSLMTPTGNP
QNILVASLSGMAYLDFLRALFPVAFLGLALQVGLLALLYPEARSLRPLPPPPPLRYRLHPGLLRKGLLVASGLLLAFLLG
YPMAQGALVAAGLLLFTRRLRSERYFMRVDWELLVMFGGLFVLTEGVRRLGLAEALLPLASSPLGLLLAATLLSLLISNV
PAVLLLAPLAKTPEEWLLLAGGSTLAGNLTLLASVANLIVAEGAGREGVRVGLLEHLRFGLPLTLFSLALLYLGLA

Sequences:

>Translated_396_residues
MALRETLSLLVLLLAYLGLALGGLPGYRMNRAGVALVGASLLVLLGALDLEEAWRALDPSTLVFLFGVMVLNAHLGYAGF
FGWVAEGLWKRARTPFALLVLLSLGSGLLSALFLNDTMALLLTPLVLRLARGLGLNPVPYLLALMAGVNTGSLMTPTGNP
QNILVASLSGMAYLDFLRALFPVAFLGLALQVGLLALLYPEARSLRPLPPPPPLRYRLHPGLLRKGLLVASGLLLAFLLG
YPMAQGALVAAGLLLFTRRLRSERYFMRVDWELLVMFGGLFVLTEGVRRLGLAEALLPLASSPLGLLLAATLLSLLISNV
PAVLLLAPLAKTPEEWLLLAGGSTLAGNLTLLASVANLIVAEGAGREGVRVGLLEHLRFGLPLTLFSLALLYLGLA
>Mature_395_residues
ALRETLSLLVLLLAYLGLALGGLPGYRMNRAGVALVGASLLVLLGALDLEEAWRALDPSTLVFLFGVMVLNAHLGYAGFF
GWVAEGLWKRARTPFALLVLLSLGSGLLSALFLNDTMALLLTPLVLRLARGLGLNPVPYLLALMAGVNTGSLMTPTGNPQ
NILVASLSGMAYLDFLRALFPVAFLGLALQVGLLALLYPEARSLRPLPPPPPLRYRLHPGLLRKGLLVASGLLLAFLLGY
PMAQGALVAAGLLLFTRRLRSERYFMRVDWELLVMFGGLFVLTEGVRRLGLAEALLPLASSPLGLLLAATLLSLLISNVP
AVLLLAPLAKTPEEWLLLAGGSTLAGNLTLLASVANLIVAEGAGREGVRVGLLEHLRFGLPLTLFSLALLYLGLA

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=227, Percent_Identity=29.0748898678414, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1787039, Length=345, Percent_Identity=31.304347826087, Blast_Score=95, Evalue=9e-21,
Organism=Drosophila melanogaster, GI28574683, Length=206, Percent_Identity=30.0970873786408, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28574681, Length=206, Percent_Identity=30.0970873786408, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28574685, Length=206, Percent_Identity=30.0970873786408, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28574678, Length=206, Percent_Identity=30.0970873786408, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19920704, Length=206, Percent_Identity=30.0970873786408, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24581759, Length=206, Percent_Identity=30.0970873786408, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI45550608, Length=416, Percent_Identity=24.2788461538462, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 42041; Mature: 41909

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRETLSLLVLLLAYLGLALGGLPGYRMNRAGVALVGASLLVLLGALDLEEAWRALDPS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCH
TLVFLFGVMVLNAHLGYAGFFGWVAEGLWKRARTPFALLVLLSLGSGLLSALFLNDTMAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLTPLVLRLARGLGLNPVPYLLALMAGVNTGSLMTPTGNPQNILVASLSGMAYLDFLRAL
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCEEEEHHHHHHHHHHHHHH
FPVAFLGLALQVGLLALLYPEARSLRPLPPPPPLRYRLHPGLLRKGLLVASGLLLAFLLG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHC
YPMAQGALVAAGLLLFTRRLRSERYFMRVDWELLVMFGGLFVLTEGVRRLGLAEALLPLA
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSPLGLLLAATLLSLLISNVPAVLLLAPLAKTPEEWLLLAGGSTLAGNLTLLASVANLIV
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHH
AEGAGREGVRVGLLEHLRFGLPLTLFSLALLYLGLA
HCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALRETLSLLVLLLAYLGLALGGLPGYRMNRAGVALVGASLLVLLGALDLEEAWRALDPS
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCH
TLVFLFGVMVLNAHLGYAGFFGWVAEGLWKRARTPFALLVLLSLGSGLLSALFLNDTMAL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLTPLVLRLARGLGLNPVPYLLALMAGVNTGSLMTPTGNPQNILVASLSGMAYLDFLRAL
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCEEEEHHHHHHHHHHHHHH
FPVAFLGLALQVGLLALLYPEARSLRPLPPPPPLRYRLHPGLLRKGLLVASGLLLAFLLG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHC
YPMAQGALVAAGLLLFTRRLRSERYFMRVDWELLVMFGGLFVLTEGVRRLGLAEALLPLA
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSPLGLLLAATLLSLLISNVPAVLLLAPLAKTPEEWLLLAGGSTLAGNLTLLASVANLIV
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHH
AEGAGREGVRVGLLEHLRFGLPLTLFSLALLYLGLA
HCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]