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The map label for this gene is accA

Identifier: 55981736

GI number: 55981736

Start: 1655920

End: 1656870

Strand: Reverse

Name: accA

Synonym: TTHA1767

Alternate gene names: 55981736

Gene position: 1656870-1655920 (Counterclockwise)

Preceding gene: 55981737

Following gene: 55981735

Centisome position: 89.57

GC content: 69.4

Gene sequence:

>951_bases
ATGCCCCTGGAGTTTGAAAAGCCCATTCTGGAGCTGGAACGGCGCATCGCCGAGCTCAAGGAGACGGCCAAGGCCACGGG
GGTGGACCTGGAGGCCGAGATCCGCCTCCTGGAGGAGCGCCTGGCCCGGCTCAGGAAGGAGACCTACGAGAACCTCACCC
CCTGGCAGCGGGTCCAGCTGGCCCGGGCCTCCGGGAGGCCCACCACCCTGGACGTCCTGGAGAAGGCCTTCCAGGACTTC
ATAGAGCTCCACGGGGACCGGGCCTTCGCCGACGACCCCGCCATCGTGGGGGGGCTCGCCTACCTGGAGGGGGAGAAGGT
GGTGGTGGTGGGGCACCAGAAGGGCCGGGACACCAAGGAGAACCTCCAGCGCAACTTCGGCATGCCCCACCCCGAGGGGT
ACCGCAAGGCCATGCGCCTCATGGACCTGGCGGACCGTTTCGGCTACCCCTTTCTCACCTTCGTGGACACCCCCGGGGCC
TACCCCGGGGTCTCCGCCGAAGAGCGGGGCCAGGCCTGGGTCATCGCCCAGAGCATTCAGCGGATGAGCCGCCTCCGGGT
CCCCGCCGTGACGGTGATCCTGGGGGAGGGGGGAAGCGGGGGGGCCTTGGCCATCGCCGTGGCCAACCGGGTCCTCATCC
TGGAGAACGCCTGGTACTCCGTGATCAGCCCGGAGTCCTGCGCCGCCATCCTCTGGCGGGACGCCAAGGAGGCCCCCAAG
GCCGCCGAGGCCTTGAAGCTCACGGCGAAGGACCTCCTCCAGCTCAAGGTGGTGGACGCCATCGTCCCCGAACCCGAGGG
CGGGGCCCATAAGGACCCCGACCGGGCCATCCGGAACATCAAGGAGGCCCTCCTAAAGGCCCTGGAGGAGCTCAAGGGCC
TCTCCCCGGAGGCCCTCTACGAGGACCGCTACCGCCGCTTCCGCTCCCTGGGCGCCTTCGCCGAGCCTTAA

Upstream 100 bases:

>100_bases
TTCCTTCTGAAGCACGGCATGGTGGACCGGGTCACGGACCGGCGCCGCCTGAAGGAGGAGCTCGTGCGGGTCCTCCGCCA
CCTGCACCCGGGAGTAGCCT

Downstream 100 bases:

>100_bases
GGGACGTTGGGCCAGGTCCCTCAGGGTTTTCACACGGAAGGCGTACCCTGGGGGTGGAGGTGAGGCCTATGCGGAAGCTG
TTGCTGGCGGTCTTGGGGCT

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MPLEFEKPILELERRIAELKETAKATGVDLEAEIRLLEERLARLRKETYENLTPWQRVQLARASGRPTTLDVLEKAFQDF
IELHGDRAFADDPAIVGGLAYLEGEKVVVVGHQKGRDTKENLQRNFGMPHPEGYRKAMRLMDLADRFGYPFLTFVDTPGA
YPGVSAEERGQAWVIAQSIQRMSRLRVPAVTVILGEGGSGGALAIAVANRVLILENAWYSVISPESCAAILWRDAKEAPK
AAEALKLTAKDLLQLKVVDAIVPEPEGGAHKDPDRAIRNIKEALLKALEELKGLSPEALYEDRYRRFRSLGAFAEP

Sequences:

>Translated_316_residues
MPLEFEKPILELERRIAELKETAKATGVDLEAEIRLLEERLARLRKETYENLTPWQRVQLARASGRPTTLDVLEKAFQDF
IELHGDRAFADDPAIVGGLAYLEGEKVVVVGHQKGRDTKENLQRNFGMPHPEGYRKAMRLMDLADRFGYPFLTFVDTPGA
YPGVSAEERGQAWVIAQSIQRMSRLRVPAVTVILGEGGSGGALAIAVANRVLILENAWYSVISPESCAAILWRDAKEAPK
AAEALKLTAKDLLQLKVVDAIVPEPEGGAHKDPDRAIRNIKEALLKALEELKGLSPEALYEDRYRRFRSLGAFAEP
>Mature_315_residues
PLEFEKPILELERRIAELKETAKATGVDLEAEIRLLEERLARLRKETYENLTPWQRVQLARASGRPTTLDVLEKAFQDFI
ELHGDRAFADDPAIVGGLAYLEGEKVVVVGHQKGRDTKENLQRNFGMPHPEGYRKAMRLMDLADRFGYPFLTFVDTPGAY
PGVSAEERGQAWVIAQSIQRMSRLRVPAVTVILGEGGSGGALAIAVANRVLILENAWYSVISPESCAAILWRDAKEAPKA
AEALKLTAKDLLQLKVVDAIVPEPEGGAHKDPDRAIRNIKEALLKALEELKGLSPEALYEDRYRRFRSLGAFAEP

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=312, Percent_Identity=52.2435897435897, Blast_Score=330, Evalue=9e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_THET8 (Q5SHG3)

Other databases:

- EMBL:   AP008226
- RefSeq:   YP_145033.1
- ProteinModelPortal:   Q5SHG3
- SMR:   Q5SHG3
- STRING:   Q5SHG3
- GeneID:   3168755
- GenomeReviews:   AP008226_GR
- KEGG:   ttj:TTHA1767
- NMPDR:   fig|300852.3.peg.1039
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- ProtClustDB:   PRK05724
- BioCyc:   TTHE300852:TTHA1767-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35179; Mature: 35048

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLEFEKPILELERRIAELKETAKATGVDLEAEIRLLEERLARLRKETYENLTPWQRVQL
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ARASGRPTTLDVLEKAFQDFIELHGDRAFADDPAIVGGLAYLEGEKVVVVGHQKGRDTKE
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHEECCCEEEEECCCCCCCHHH
NLQRNFGMPHPEGYRKAMRLMDLADRFGYPFLTFVDTPGAYPGVSAEERGQAWVIAQSIQ
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCCCHHHHHHHH
RMSRLRVPAVTVILGEGGSGGALAIAVANRVLILENAWYSVISPESCAAILWRDAKEAPK
HHHHCCCCEEEEEEECCCCCCEEEEEECCEEEEEECCCHHHCCCHHHHHHHHHHHHHCHH
AAEALKLTAKDLLQLKVVDAIVPEPEGGAHKDPDRAIRNIKEALLKALEELKGLSPEALY
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EDRYRRFRSLGAFAEP
HHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PLEFEKPILELERRIAELKETAKATGVDLEAEIRLLEERLARLRKETYENLTPWQRVQL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ARASGRPTTLDVLEKAFQDFIELHGDRAFADDPAIVGGLAYLEGEKVVVVGHQKGRDTKE
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHEECCCEEEEECCCCCCCHHH
NLQRNFGMPHPEGYRKAMRLMDLADRFGYPFLTFVDTPGAYPGVSAEERGQAWVIAQSIQ
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCCCHHHHHHHH
RMSRLRVPAVTVILGEGGSGGALAIAVANRVLILENAWYSVISPESCAAILWRDAKEAPK
HHHHCCCCEEEEEEECCCCCCEEEEEECCEEEEEECCCHHHCCCHHHHHHHHHHHHHCHH
AAEALKLTAKDLLQLKVVDAIVPEPEGGAHKDPDRAIRNIKEALLKALEELKGLSPEALY
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
EDRYRRFRSLGAFAEP
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA