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The map label for this gene is yggV [C]

Identifier: 55981623

GI number: 55981623

Start: 1569506

End: 1570129

Strand: Reverse

Name: yggV [C]

Synonym: TTHA1654

Alternate gene names: 55981623

Gene position: 1570129-1569506 (Counterclockwise)

Preceding gene: 55981624

Following gene: 55981622

Centisome position: 84.88

GC content: 70.51

Gene sequence:

>624_bases
ATGCTTAGGGGGATGAAGGTGGTCCTGGCCACCGGCAACCCCGGGAAGGTGCGGGAGCTCAAGGAGGGCCTCGCCCCCTT
GGGCTGGACCCTCCTCACCCTGGCGGACTTCGCCTTGCGCATGCCCAAGGAGGAGGGGGCCACCTTCCTGGAGAACGCCC
TCCTCAAGGCGGCGTACGTGGCCAAGGCCACGGGGCTTCCCGCCCTCGCCGACGACTCCGGCCTCGAGGTCTACGCCCTC
GGGGGCGAGCCCGGGGTCTACTCCGCCCGCTACGGGGGGAGGGCCACGGACCGGGAGCGGAACGTCTACCTCCTGGAGAG
GATGCGCCACCTCAAAGGGGAGGAGCGCAAGGCCCGCTTCGTGGCCGTCCTGGTCCTGGCCTACCCCGACGGGCACGCCG
AGGCCTACGAGGGGAGCGTGGAGGGGGTGATCCTCGAGGCCCCCCGGGGCGAGGGGGGCTTCGGCTACGATCCCCTCTTC
TACGTCCCTGAGGCGGGGAAGACCTTCGCCGAGATGGGCCTAGAGGAGAAGGCCCGGTACTCCCACCGGGGAAAGGCCCT
TAGGGCCCTCCTCGAGGCCTACAAGGACGGGCCGCCCCCGAGGGAGGTCTCCAAGCTGGAATGA

Upstream 100 bases:

>100_bases
CGAGGCCGCGGCCCAGGCCCTGGAGGCCCTGCCTCCGAGCCCCTTCCGGGAGGCCTTGCGGGAGCTCGCCCTGAAGGAGG
CGGAGCGGGTCCGCTAGGGT

Downstream 100 bases:

>100_bases
ACGTCCTCTCCCCCCACATCGCCCTCTACCGCCTCTTTGACGTGGCCGACGAGATTGACCTAGGCCGTCTTTCCACGCCC
CGCCTCCGCCTCTCCCGGGC

Product: deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MLRGMKVVLATGNPGKVRELKEGLAPLGWTLLTLADFALRMPKEEGATFLENALLKAAYVAKATGLPALADDSGLEVYAL
GGEPGVYSARYGGRATDRERNVYLLERMRHLKGEERKARFVAVLVLAYPDGHAEAYEGSVEGVILEAPRGEGGFGYDPLF
YVPEAGKTFAEMGLEEKARYSHRGKALRALLEAYKDGPPPREVSKLE

Sequences:

>Translated_207_residues
MLRGMKVVLATGNPGKVRELKEGLAPLGWTLLTLADFALRMPKEEGATFLENALLKAAYVAKATGLPALADDSGLEVYAL
GGEPGVYSARYGGRATDRERNVYLLERMRHLKGEERKARFVAVLVLAYPDGHAEAYEGSVEGVILEAPRGEGGFGYDPLF
YVPEAGKTFAEMGLEEKARYSHRGKALRALLEAYKDGPPPREVSKLE
>Mature_207_residues
MLRGMKVVLATGNPGKVRELKEGLAPLGWTLLTLADFALRMPKEEGATFLENALLKAAYVAKATGLPALADDSGLEVYAL
GGEPGVYSARYGGRATDRERNVYLLERMRHLKGEERKARFVAVLVLAYPDGHAEAYEGSVEGVILEAPRGEGGFGYDPLF
YVPEAGKTFAEMGLEEKARYSHRGKALRALLEAYKDGPPPREVSKLE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=199, Percent_Identity=51.7587939698493, Blast_Score=184, Evalue=4e-48,
Organism=Drosophila melanogaster, GI19920712, Length=199, Percent_Identity=32.6633165829146, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22556; Mature: 22556

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRGMKVVLATGNPGKVRELKEGLAPLGWTLLTLADFALRMPKEEGATFLENALLKAAYV
CCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHH
AKATGLPALADDSGLEVYALGGEPGVYSARYGGRATDRERNVYLLERMRHLKGEERKARF
HHHCCCCCCCCCCCCEEEEECCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHEE
VAVLVLAYPDGHAEAYEGSVEGVILEAPRGEGGFGYDPLFYVPEAGKTFAEMGLEEKARY
EEEEEEECCCCCCHHHCCCCCEEEEECCCCCCCCCCCCEEEECCCCHHHHHCCHHHHHHH
SHRGKALRALLEAYKDGPPPREVSKLE
HHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLRGMKVVLATGNPGKVRELKEGLAPLGWTLLTLADFALRMPKEEGATFLENALLKAAYV
CCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHH
AKATGLPALADDSGLEVYALGGEPGVYSARYGGRATDRERNVYLLERMRHLKGEERKARF
HHHCCCCCCCCCCCCEEEEECCCCCCEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHEE
VAVLVLAYPDGHAEAYEGSVEGVILEAPRGEGGFGYDPLFYVPEAGKTFAEMGLEEKARY
EEEEEEECCCCCCHHHCCCCCEEEEECCCCCCCCCCCCEEEECCCCHHHHHCCHHHHHHH
SHRGKALRALLEAYKDGPPPREVSKLE
HHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA