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The map label for this gene is xerC [H]

Identifier: 55981508

GI number: 55981508

Start: 1465735

End: 1466616

Strand: Direct

Name: xerC [H]

Synonym: TTHA1539

Alternate gene names: 55981508

Gene position: 1465735-1466616 (Clockwise)

Preceding gene: 55981507

Following gene: 55981510

Centisome position: 79.24

GC content: 64.74

Gene sequence:

>882_bases
ATGCGGGGCACAATCACGGACTGGGCGGAAGCTTGGCTTCTGGACTGCAGGGCTAGGGGGCTTTCCCCGAACACCATCGG
CTACTACCGGGACGCGGTGAAGGCTATGGTGAAGGTGGTGGGCGACAAACCCATGGCGGAGCTTACGGCGGACGACCTTC
GGGCCTTCCTCGTGAAGTCCTTTGAAGACGGCCTTAGCCCCGGCGGCGTGGCGGCTAGGTGGCGGGCGGCGCGGGCCTTT
GTGCGGTGGGCGGTGAAGGAAGGGGCCCTCGGTGTTGACCCCACGGGGAAAATCAGGCCGCCTAAGGTGCCCGAAGCGGA
CCTTCCCGTGGTGCGGGAATGGGAAGTGAAGAAGCTTCTTGCGGCGGCGGAAATGGGGAAGAACCCACTAAGGGACAAGG
CCCTGGTGATGGTGCTTTGGGACACGGGCCTACGGGCCAGCGAGGTTCTCGGGCTTCGGGTTTCGGATGTCAAGGCGGAA
GCGGTGCGGGTTCGGCGGAAGGGCGGGGCCGTGCAATGGGTGCCGGTGAGCCTTCCCACCTACCGGGCCATCCTCGCCTA
CGCCCGGGCGGAGCGTCCCCCTTCGGACCATGACGCTTTATTCTTGACCCGAAGCGGTTTGCCCTTGGCGTATGACGGCT
TGAAGATGGTCCTTCGGCGGCTAGCGGAATACGCGGGCCTTCCCCCCAAGCCGCCGCACGCCTTCCGGCGCGGCGCGGCG
GTGGCGATGGTCAAGAACGGGATGCCTTCCTACGCGCTTCAAGCGATGCTCGGGCACAAGTCCCCGGTGATGACCGCCCA
CTATGTGCGGCTTGCGGAAAAAGACCTCAGGGAAATCCACCGGACAGCTTCACCCGTCATCGGCTTGATAAAGCGGCAAT
AA

Upstream 100 bases:

>100_bases
CCACTTCGGTTAGCATTGGCCGCCCCCGCCCCGAAAAGTCGTGAAGAGGGCAAATCGTCAGGGCATAGAAGGGGAAAACC
GGTAGTCGTGGAGGTAAAAT

Downstream 100 bases:

>100_bases
TCTCGCCCGTGGGGTCCAGAAGCGCCCCGACAACCTCGCGCAAGGGGGCACGCCAATATGCCGACCGCCAGCGGGCGCGG
CCCCACCTTGACTGATTGGT

Product: phage integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MRGTITDWAEAWLLDCRARGLSPNTIGYYRDAVKAMVKVVGDKPMAELTADDLRAFLVKSFEDGLSPGGVAARWRAARAF
VRWAVKEGALGVDPTGKIRPPKVPEADLPVVREWEVKKLLAAAEMGKNPLRDKALVMVLWDTGLRASEVLGLRVSDVKAE
AVRVRRKGGAVQWVPVSLPTYRAILAYARAERPPSDHDALFLTRSGLPLAYDGLKMVLRRLAEYAGLPPKPPHAFRRGAA
VAMVKNGMPSYALQAMLGHKSPVMTAHYVRLAEKDLREIHRTASPVIGLIKRQ

Sequences:

>Translated_293_residues
MRGTITDWAEAWLLDCRARGLSPNTIGYYRDAVKAMVKVVGDKPMAELTADDLRAFLVKSFEDGLSPGGVAARWRAARAF
VRWAVKEGALGVDPTGKIRPPKVPEADLPVVREWEVKKLLAAAEMGKNPLRDKALVMVLWDTGLRASEVLGLRVSDVKAE
AVRVRRKGGAVQWVPVSLPTYRAILAYARAERPPSDHDALFLTRSGLPLAYDGLKMVLRRLAEYAGLPPKPPHAFRRGAA
VAMVKNGMPSYALQAMLGHKSPVMTAHYVRLAEKDLREIHRTASPVIGLIKRQ
>Mature_293_residues
MRGTITDWAEAWLLDCRARGLSPNTIGYYRDAVKAMVKVVGDKPMAELTADDLRAFLVKSFEDGLSPGGVAARWRAARAF
VRWAVKEGALGVDPTGKIRPPKVPEADLPVVREWEVKKLLAAAEMGKNPLRDKALVMVLWDTGLRASEVLGLRVSDVKAE
AVRVRRKGGAVQWVPVSLPTYRAILAYARAERPPSDHDALFLTRSGLPLAYDGLKMVLRRLAEYAGLPPKPPHAFRRGAA
VAMVKNGMPSYALQAMLGHKSPVMTAHYVRLAEKDLREIHRTASPVIGLIKRQ

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=278, Percent_Identity=28.4172661870504, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790244, Length=281, Percent_Identity=26.6903914590747, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790767, Length=161, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 32270; Mature: 32270

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGTITDWAEAWLLDCRARGLSPNTIGYYRDAVKAMVKVVGDKPMAELTADDLRAFLVKS
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FEDGLSPGGVAARWRAARAFVRWAVKEGALGVDPTGKIRPPKVPEADLPVVREWEVKKLL
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AAAEMGKNPLRDKALVMVLWDTGLRASEVLGLRVSDVKAEAVRVRRKGGAVQWVPVSLPT
HHHHHCCCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCHH
YRAILAYARAERPPSDHDALFLTRSGLPLAYDGLKMVLRRLAEYAGLPPKPPHAFRRGAA
HHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHHCCCE
VAMVKNGMPSYALQAMLGHKSPVMTAHYVRLAEKDLREIHRTASPVIGLIKRQ
EEHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRGTITDWAEAWLLDCRARGLSPNTIGYYRDAVKAMVKVVGDKPMAELTADDLRAFLVKS
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FEDGLSPGGVAARWRAARAFVRWAVKEGALGVDPTGKIRPPKVPEADLPVVREWEVKKLL
HHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AAAEMGKNPLRDKALVMVLWDTGLRASEVLGLRVSDVKAEAVRVRRKGGAVQWVPVSLPT
HHHHHCCCCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCHH
YRAILAYARAERPPSDHDALFLTRSGLPLAYDGLKMVLRRLAEYAGLPPKPPHAFRRGAA
HHHHHHHHHHCCCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHHCCCE
VAMVKNGMPSYALQAMLGHKSPVMTAHYVRLAEKDLREIHRTASPVIGLIKRQ
EEHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA