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The map label for this gene is ppsA [H]

Identifier: 55981469

GI number: 55981469

Start: 1427866

End: 1430259

Strand: Direct

Name: ppsA [H]

Synonym: TTHA1500

Alternate gene names: 55981469

Gene position: 1427866-1430259 (Clockwise)

Preceding gene: 55981468

Following gene: 55981470

Centisome position: 77.19

GC content: 67.92

Gene sequence:

>2394_bases
GTGAGGTGGGTGCGGTTTTTCCACGAGGTGGGCCTCGAGGACGTCCCCCTGGTGGGGGGGAAGAACGCCTCCCTGGGGGA
GATGATCCGGGAGCTCTCCCCCTTAGGGGTCAGGGTGCCCGAGGGCTTCGCCACCACCAGCGAGGCGTATTGGCACTTTC
TGGAGCATAACGGCCTGAAAGAGGCCATCGCCCGGGAACTGGGGGAGCTGGACCCGGAGGACCCCAAGGCCCTGCAAAGG
GTAAGCCGCCGCCTGCGGAACCTGATCCTGAAGGGCGAATACCCCCAAGACCTCCGGGAGGAGATCCTCGAGGCCTACCG
CAGGCTTTCCGAGGAGGCGGGGGAGGAGGAGATCCCCGTGGCCGTGCGGAGTAGCGCCACCGCCGAGGACCTCCCCACGG
CGAGCTTCGCCGGACAGCAGGAAAGCTTTCTCTACGTCCAGGGGGAAGCGGACCTCCTCCTCCACGTGAAGCGGGCCATG
GCGAGCCTCTTCACGGCGCGGGCCATCAGCTACCGGGCCCACATGGGCTTTGACCACCTCAAGGTGGCCCTCTCCGTGGG
GGTCCAGCGCATGGTGCGGGCGGACGACGCCGCAAGCGGGGTCATCTTCACCTTGGACCCCGACACCGGCCACCGGGGCT
TCGTCTACCTCACGGCCATCTACGGCCTGGGCGAGAACATCGTCCAGGGCCGGGTGATTCCGGACGGCTACTACGTGCAC
AAGGAGACCTTCCGTGAGGGCTTCCGGGCCGTGGTCTACAGAAGGCTCGGCGCCAAGGAGCTCACCCTGGCCTTTGACCC
CAGGGAGGGAAGGCTCAAGAACCGCCCCACGCCCCTCTACCTGCGAAACCGCTTCGCCCTAAGGGACGAGGAGGTCCTCC
TCCTTGCCGACTGGGCCATGAAGATTGAGGACCACTACTCCAAGAAGCGGGGTAGCCCCACCCCCATGGACATTGAGTGG
GCCAAGGACGGCCCCACGGGGGAGCTCTTCGTCCTCCAGGCCCGGCCCGAGACCGTCCACTCGCAAAAGACCCCGGTCCT
CCGCGTCTTCCGCCTCCTCAAGCGGGGCGAGGTCCTGGCCGAGGGCCTCGCCGTGGGGGAGGCCATCGCCATGGGGCGGG
CCCGCGTCCTCAAGGACCCGAAGGAGATGGACCGCTTCCAGGAGGGGGAGGTCCTGGTCACCGAGACCACCAACCCCGAC
TGGGAGCCCATCATGAAGAAGGCGGCGGCCATCGTCACCGAAAGGGGCGGGCGCACCTCCCACGCGGCCATCGTGGCCCG
GGAGCTGGGGGTGCCCGCGGTGGTGGGGGCGGTGGGGGCCACGCGGAGCGTCCCCGAGGGGGAGGAGGTCACGGTCTCCT
GCGCCGAGGGGGAGCGGGGCGTGGTCTACCGTGGGAGGCTCCCCTTTGAGGTGGAGGAGATCCGCCCCGAAACCCTGCCC
AGGACCCGGACCCGGATCCTGGTGAACGTGGGCACCCCGGAGGAGGCCCTGAGGACGAGCCTCCTTCCCACGGACGGGGT
GGGGCTTTTGCGCATGGAGTTCGTCTTCGCGAGCCACGTGCGTGTCCACCCCCTGGCCCTCACCCGGTTTGAAACCCTGC
CCAAGGAGGTGCGCCGCCAGGTGGAGGAGGTCACCGAGGCCTACCCCGACAAGCGGGCCTACTTCGTGGAGACCTTAAGC
CAGGGCATCGGCCTCATCGCCGCCGCCTTCTATCCGAGGCCCGTTCTCCTCCGCTTCTCCGACTTCAAGACCAACGAGTA
CGCCCGCCTCCTCGGGGGGCACCTCTTTGAGCCCAAGGAGGAAAACCCCATGCTGGGGTGGCGGGGGGCGAGCCGCTACT
ACCACCCGGACTACAAGGAGGGCTTCCTCCTGGAGGTGGCCGCGGTGAGGCGGGTTAGGGAGGAGATGGGCCTCAAGAAC
CTCATGGTCATGGTCCCCTTCTGCCGCACCCCGGAGGAGGGGGAGAAGGTCTTGGAGGTGATGGCCGAAGGGGGGCTTAG
GCGGGGAGAGGGGGGCCTCGAGGTCCACGTGATGGCGGAGATCCCCTCCAACGTCCTCGAGGCCGAGGCCTTCGCCGAGC
TCTTTGACGGCTTCTCCATCGGCTCCAACGACCTCACCCAGCTCGCTTTGGGCCTGGACCGGGACTCGGAAAGGGTGGCC
CACCTCTTTGACGAGCGGCGGGAGACGGTGAAGCGCCTCGCGGCCATGCTCATTGAGAAGGCCCACGCCAAGGGGAAGAA
GGTGGGCATCTGCGGCCAGGCTCCTTCCGACTACCCCGAGTTCGCCGCCTTCCTGGTGGAACGGGGCATAGACTCCCTAA
GCCTCAACCCCGATGCCCTCCTGCGCACGGTGCGGGAGGTGGCCGAGGTGGAAAGGAGGCTCGGGATCGGGTAG

Upstream 100 bases:

>100_bases
TCGCCCTCCCCCACCGCCTCTTCCTCACGGAGGAGGCCCTTTACGCGGGGGAAAGCGCCGAGGGCGTGCTGAAGGAGGCT
TTGAGGAAAGGAGGGATCCC

Downstream 100 bases:

>100_bases
CCTGGGGCATGGTCCGCGAGCCCTTCAACGCCCTGAGCCACGCCCTCGGGGTGCCCCTCGCCCTCCTCGGAGGCCTCCTT
CTCCTCCTCCTGGCCCCCAG

Product: phosphoenolpyruvate synthase

Products: NA

Alternate protein names: PEP synthase; Pyruvate, water dikinase [H]

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:

>797_residues
MRWVRFFHEVGLEDVPLVGGKNASLGEMIRELSPLGVRVPEGFATTSEAYWHFLEHNGLKEAIARELGELDPEDPKALQR
VSRRLRNLILKGEYPQDLREEILEAYRRLSEEAGEEEIPVAVRSSATAEDLPTASFAGQQESFLYVQGEADLLLHVKRAM
ASLFTARAISYRAHMGFDHLKVALSVGVQRMVRADDAASGVIFTLDPDTGHRGFVYLTAIYGLGENIVQGRVIPDGYYVH
KETFREGFRAVVYRRLGAKELTLAFDPREGRLKNRPTPLYLRNRFALRDEEVLLLADWAMKIEDHYSKKRGSPTPMDIEW
AKDGPTGELFVLQARPETVHSQKTPVLRVFRLLKRGEVLAEGLAVGEAIAMGRARVLKDPKEMDRFQEGEVLVTETTNPD
WEPIMKKAAAIVTERGGRTSHAAIVARELGVPAVVGAVGATRSVPEGEEVTVSCAEGERGVVYRGRLPFEVEEIRPETLP
RTRTRILVNVGTPEEALRTSLLPTDGVGLLRMEFVFASHVRVHPLALTRFETLPKEVRRQVEEVTEAYPDKRAYFVETLS
QGIGLIAAAFYPRPVLLRFSDFKTNEYARLLGGHLFEPKEENPMLGWRGASRYYHPDYKEGFLLEVAAVRRVREEMGLKN
LMVMVPFCRTPEEGEKVLEVMAEGGLRRGEGGLEVHVMAEIPSNVLEAEAFAELFDGFSIGSNDLTQLALGLDRDSERVA
HLFDERRETVKRLAAMLIEKAHAKGKKVGICGQAPSDYPEFAAFLVERGIDSLSLNPDALLRTVREVAEVERRLGIG

Sequences:

>Translated_797_residues
MRWVRFFHEVGLEDVPLVGGKNASLGEMIRELSPLGVRVPEGFATTSEAYWHFLEHNGLKEAIARELGELDPEDPKALQR
VSRRLRNLILKGEYPQDLREEILEAYRRLSEEAGEEEIPVAVRSSATAEDLPTASFAGQQESFLYVQGEADLLLHVKRAM
ASLFTARAISYRAHMGFDHLKVALSVGVQRMVRADDAASGVIFTLDPDTGHRGFVYLTAIYGLGENIVQGRVIPDGYYVH
KETFREGFRAVVYRRLGAKELTLAFDPREGRLKNRPTPLYLRNRFALRDEEVLLLADWAMKIEDHYSKKRGSPTPMDIEW
AKDGPTGELFVLQARPETVHSQKTPVLRVFRLLKRGEVLAEGLAVGEAIAMGRARVLKDPKEMDRFQEGEVLVTETTNPD
WEPIMKKAAAIVTERGGRTSHAAIVARELGVPAVVGAVGATRSVPEGEEVTVSCAEGERGVVYRGRLPFEVEEIRPETLP
RTRTRILVNVGTPEEALRTSLLPTDGVGLLRMEFVFASHVRVHPLALTRFETLPKEVRRQVEEVTEAYPDKRAYFVETLS
QGIGLIAAAFYPRPVLLRFSDFKTNEYARLLGGHLFEPKEENPMLGWRGASRYYHPDYKEGFLLEVAAVRRVREEMGLKN
LMVMVPFCRTPEEGEKVLEVMAEGGLRRGEGGLEVHVMAEIPSNVLEAEAFAELFDGFSIGSNDLTQLALGLDRDSERVA
HLFDERRETVKRLAAMLIEKAHAKGKKVGICGQAPSDYPEFAAFLVERGIDSLSLNPDALLRTVREVAEVERRLGIG
>Mature_797_residues
MRWVRFFHEVGLEDVPLVGGKNASLGEMIRELSPLGVRVPEGFATTSEAYWHFLEHNGLKEAIARELGELDPEDPKALQR
VSRRLRNLILKGEYPQDLREEILEAYRRLSEEAGEEEIPVAVRSSATAEDLPTASFAGQQESFLYVQGEADLLLHVKRAM
ASLFTARAISYRAHMGFDHLKVALSVGVQRMVRADDAASGVIFTLDPDTGHRGFVYLTAIYGLGENIVQGRVIPDGYYVH
KETFREGFRAVVYRRLGAKELTLAFDPREGRLKNRPTPLYLRNRFALRDEEVLLLADWAMKIEDHYSKKRGSPTPMDIEW
AKDGPTGELFVLQARPETVHSQKTPVLRVFRLLKRGEVLAEGLAVGEAIAMGRARVLKDPKEMDRFQEGEVLVTETTNPD
WEPIMKKAAAIVTERGGRTSHAAIVARELGVPAVVGAVGATRSVPEGEEVTVSCAEGERGVVYRGRLPFEVEEIRPETLP
RTRTRILVNVGTPEEALRTSLLPTDGVGLLRMEFVFASHVRVHPLALTRFETLPKEVRRQVEEVTEAYPDKRAYFVETLS
QGIGLIAAAFYPRPVLLRFSDFKTNEYARLLGGHLFEPKEENPMLGWRGASRYYHPDYKEGFLLEVAAVRRVREEMGLKN
LMVMVPFCRTPEEGEKVLEVMAEGGLRRGEGGLEVHVMAEIPSNVLEAEAFAELFDGFSIGSNDLTQLALGLDRDSERVA
HLFDERRETVKRLAAMLIEKAHAKGKKVGICGQAPSDYPEFAAFLVERGIDSLSLNPDALLRTVREVAEVERRLGIG

Specific function: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate [H]

COG id: COG0574

COG function: function code G; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEP-utilizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787994, Length=792, Percent_Identity=50.5050505050505, Blast_Score=791, Evalue=0.0,
Organism=Escherichia coli, GI1788756, Length=431, Percent_Identity=26.2180974477958, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1789193, Length=398, Percent_Identity=27.8894472361809, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1788726, Length=373, Percent_Identity=25.7372654155496, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI48994992, Length=367, Percent_Identity=25.6130790190736, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17564524, Length=243, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR008279
- InterPro:   IPR006318
- InterPro:   IPR006319
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR002192
- InterPro:   IPR015813 [H]

Pfam domain/function: PF00391 PEP-utilizers; PF02896 PEP-utilizers_C; PF01326 PPDK_N [H]

EC number: =2.7.9.2 [H]

Molecular weight: Translated: 89226; Mature: 89226

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00370 PEP_ENZYMES_PHOS_SITE ; PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWVRFFHEVGLEDVPLVGGKNASLGEMIRELSPLGVRVPEGFATTSEAYWHFLEHNGLK
CHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHCCHH
EAIARELGELDPEDPKALQRVSRRLRNLILKGEYPQDLREEILEAYRRLSEEAGEEEIPV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
AVRSSATAEDLPTASFAGQQESFLYVQGEADLLLHVKRAMASLFTARAISYRAHMGFDHL
EECCCCCHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KVALSVGVQRMVRADDAASGVIFTLDPDTGHRGFVYLTAIYGLGENIVQGRVIPDGYYVH
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEEHHCCCHHHCCEECCCCEEEE
KETFREGFRAVVYRRLGAKELTLAFDPREGRLKNRPTPLYLRNRFALRDEEVLLLADWAM
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCEEECCCCEEEEEHHHH
KIEDHYSKKRGSPTPMDIEWAKDGPTGELFVLQARPETVHSQKTPVLRVFRLLKRGEVLA
HHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHH
EGLAVGEAIAMGRARVLKDPKEMDRFQEGEVLVTETTNPDWEPIMKKAAAIVTERGGRTS
HHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCH
HAAIVARELGVPAVVGAVGATRSVPEGEEVTVSCAEGERGVVYRGRLPFEVEEIRPETLP
HHHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCHHHCCCCCCC
RTRTRILVNVGTPEEALRTSLLPTDGVGLLRMEFVFASHVRVHPLALTRFETLPKEVRRQ
CCCEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHH
VEEVTEAYPDKRAYFVETLSQGIGLIAAAFYPRPVLLRFSDFKTNEYARLLGGHLFEPKE
HHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCCCCC
ENPMLGWRGASRYYHPDYKEGFLLEVAAVRRVREEMGLKNLMVMVPFCRTPEEGEKVLEV
CCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHEEEEECCCCCCHHHHHHHHH
MAEGGLRRGEGGLEVHVMAEIPSNVLEAEAFAELFDGFSIGSNDLTQLALGLDRDSERVA
HHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHH
HLFDERRETVKRLAAMLIEKAHAKGKKVGICGQAPSDYPEFAAFLVERGIDSLSLNPDAL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHH
LRTVREVAEVERRLGIG
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRWVRFFHEVGLEDVPLVGGKNASLGEMIRELSPLGVRVPEGFATTSEAYWHFLEHNGLK
CHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHCCHH
EAIARELGELDPEDPKALQRVSRRLRNLILKGEYPQDLREEILEAYRRLSEEAGEEEIPV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
AVRSSATAEDLPTASFAGQQESFLYVQGEADLLLHVKRAMASLFTARAISYRAHMGFDHL
EECCCCCHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KVALSVGVQRMVRADDAASGVIFTLDPDTGHRGFVYLTAIYGLGENIVQGRVIPDGYYVH
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEEHHCCCHHHCCEECCCCEEEE
KETFREGFRAVVYRRLGAKELTLAFDPREGRLKNRPTPLYLRNRFALRDEEVLLLADWAM
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCEEECCCCEEEEEHHHH
KIEDHYSKKRGSPTPMDIEWAKDGPTGELFVLQARPETVHSQKTPVLRVFRLLKRGEVLA
HHHHHHHHCCCCCCCCEEEECCCCCCCCEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHH
EGLAVGEAIAMGRARVLKDPKEMDRFQEGEVLVTETTNPDWEPIMKKAAAIVTERGGRTS
HHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCH
HAAIVARELGVPAVVGAVGATRSVPEGEEVTVSCAEGERGVVYRGRLPFEVEEIRPETLP
HHHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEECCCCCCHHHCCCCCCC
RTRTRILVNVGTPEEALRTSLLPTDGVGLLRMEFVFASHVRVHPLALTRFETLPKEVRRQ
CCCEEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHH
VEEVTEAYPDKRAYFVETLSQGIGLIAAAFYPRPVLLRFSDFKTNEYARLLGGHLFEPKE
HHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCCCCC
ENPMLGWRGASRYYHPDYKEGFLLEVAAVRRVREEMGLKNLMVMVPFCRTPEEGEKVLEV
CCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHEEEEECCCCCCHHHHHHHHH
MAEGGLRRGEGGLEVHVMAEIPSNVLEAEAFAELFDGFSIGSNDLTQLALGLDRDSERVA
HHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHH
HLFDERRETVKRLAAMLIEKAHAKGKKVGICGQAPSDYPEFAAFLVERGIDSLSLNPDAL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHH
LRTVREVAEVERRLGIG
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]